135 results for "Muhammad Hashim"
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Harnessing Information Systems & Technology with Supply Chain Management for Performance Excellence in Retail Sector
Purpose: Retailers are revolutionizing the ways they manage their operations and supply chains to meet customer's ever changing needs. Advancements in Information Technology (IT) and Information System (IS) are supporting the companies to achieve this goal. Core activities of a retailer; stock…
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HIV/AIDS and Syphilis Screening Among High Risk Groups
Background: To screen high risk groups for HIV/AIDS and Syphilis Methods: In this cross sectional study high risk groups , i.e., transgenders, female sex workers (FSW), males sex workers (MSW), intravenous drug users (IVDUs) and long run truck drivers were screened for HIV and Syphilis. One hundred…
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Identification of an autosomal recessive stuttering locus on chromosome 3q13.2–3q13.33
Stuttering is a common speech disorder with substantial genetic contributions. To better understand the genetic factors involved in stuttering, we performed a genome-wide linkage study in a newly-ascertained consanguineous stuttering family from Pakistan. A linkage scan in this family using…
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A Case of Necrotic Hepatocellular Carcinoma in a Young Male with Hepatitis B
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Development and validation of a reversed-phase HPLC-UV method for simultaneous determination of levosulpiride and omeprazole in human plasma: Applicability of the method for evaluation of pharmacokinetic drug-drug interactions
Levosulpiride and omeprazole are co-prescribed for gastrointestinal disorders associated with depression and anxiety. Objective of the study was to develop a sensitive, robust and simple method for simultaneous analysis of levosulpiride and omeprazole in human plasma and applicability of the method…
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Gigantic retroperitoneal metastatic seminoma encasing the aorta in a young man
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Effect of Disproportional Voting Rights on Firm’s Market Performance: Evidence from Chinese Firms Cross-Listed on U.S. Exchanges
Dual-class firms face great criticism as it is believed that firms choose this structure to expropriate minority shareholders’ wealth. We compare market performance of Chinese dual-class firms with their single-class counterparts by constructing a list of Chinese firms cross-listed on U.S…
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Optogenetics for Investigating and Targeting Hallmark Traits of Cancer
The light-mediated, specific, and precise control of cell functions enabled by optogenetics has become a versatile method for investigating and combatting cancer. An increasing set of optogenetic tools enables tightly controlled regulation of ion flux across biological membranes, gene expression…
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In-Vitro Dissolution Profile Comparison of Fixed Dose Combination Suspension Containing Ibuprofen and Loratadine with Their Corresponding Marketed Suspensions
(1) Background: Fixed-dose combination (FDC) improves patient convenience and therapeutic adherence by combining suitable drugs in a single dose form. This study examined the in vitro dissolution of an ibuprofen-loratadine FDC oral suspension to commercial reference formulations. (2) Methods: The…
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Primary Spontaneous Pneumothorax in Typhoid
We report a rare case of a 12-year-old girl who presented with a short history of diarrhea, vomiting and fever after traveling to Pakistan. During the course of initial investigations, her chest radiograph showed a primary spontaneous pneumothorax. There was no previous history of pulmonary…
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Journal Article
Transforming Healthcare with Artificial Intelligence in Pakistan: A Comprehensive Overview
Artificial Intelligence (AI) is transforming healthcare globally, including in Pakistan. This research journal paper provides an overview of the role and significance of AI in healthcare, ethical considerations, regulatory frameworks, challenges faced by AI healthcare startups, and the current…
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Hepatic Candidiasis in an Immunocompetent Patient: A Diagnostic Challenge
Hepatic candidiasis is a manifestation of disseminated candidiasis, which typically presents in immunocompromised patients. Focal hepatic candidiasis in immunocompetent patients, however, is infrequent/extremely rare. We present the case of an immunocompetent female patient who presented with…
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Thyroid Storm Presenting as Acute Liver Failure in a Patient with Graves’ Disease
Although mild elevations in liver enzymes are relatively common in thyrotoxicosis, acute liver failure (ALF) is an infrequent occurrence. Despite the emergence of liver transplantation as a viable treatment for ALF, survival rates continue to remain unsatisfactory, coupled with higher rates of…
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Cross-Sectional Analysis of Impulse Indicator Saturation Method for Outlier Detection Estimated via Regularization Techniques with Application of COVID-19 Data
Impulse indicator saturation is a popular method for outlier detection in time series modeling, which outperforms the least trimmed squares (LTS), M-estimator, and MM-estimator. However, using the IIS method for outlier detection in cross-sectional analysis has remained unexplored. In this paper…
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Static Compaction on Coupled Precursors and Optimizing Molarity for Enhanced Strength and Durability of Geopolymer
The static compaction technique emphasizes the reduced activator dosage required to develop geopolymers. Therefore, it is crucial to comprehend the optimal alkaline activator concentration for blending low-calcium precursor (fly ash) with high-calcium precursor (GGBS) to produce geopolymer blocks…
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Physical Cleaning of Lakhra Coal by Dense Medium Separation Method
This research is an attempt to upgrade Lakhra Lignite Coal using ?Dense Medium Separation? technique, to make it techno-environmentally acceptable product for different industries. The air-dried samples of ROM (Run of Mine) coal were crushed, screened, ground and subjected to initial analysis and…
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Use of Novel oral anticoagulants (NOACs) in patients with risk of stroke in non valvular Atrial Fibrillation (AF)
Background: Warfarin was used for decades to prevent stroke in high risk AF patients, recent guidelines and published data is recommending use of NOACs like Rivaroxaban as an alternative to Warfarin, Its use is increasing world over because of its predictable action, less food and drug interaction…
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Geospatial Assessment of Carbon Stock Inventory by Vegetation Indices in Pai Forest, Sindh, Pakistan
Ranking 5th at global Climate Vulnerability Index, Pakistan is facing massive decline in the forest cover. Therefore, carbon stock of Pai Forest has been investigated which is converted from a riverine-to-irrigated forest. This study incorporates the direct and indirect carbon stock inventory…