14 hasil untuk "Na Lin"
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Artikel Jurnal Teks lengkap
Optimization design and application of library face recognition access control system based on improved PCA
The application of face recognition technology in Library Access Control System (LACS) has an important impact on improving the security and management efficiency of the library. However, the traditional face recognition methods have some limitations in the face of complex environmental conditions…
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Affecting Rhomboid-3 Function Causes a Dilated Heart in Adult Drosophila
Drosophila is a well recognized model of several human diseases, and recent investigations have demonstrated that Drosophila can be used as a model of human heart failure. Previously, we described that optical coherence tomography (OCT) can be used to rapidly examine the cardiac function in adult…
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Associations between Methylenetetrahydrofolate Reductase (MTHFR) Polymorphisms and Non-Alcoholic Fatty Liver Disease (NAFLD) Risk: A Meta-Analysis
Background: C677T and A1298C are the most common allelic variants of Methylenetetrahydrofolate Reductase (MTHFR) gene. The association between MTHFR polymorphisms and the occurrence of non-alcoholic fatty liver disease (NAFLD) remains controversial. This study was thus performed to examine whether…
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Genetic etiology and pregnancy outcomes of abnormal fluid accumulation in fetus: A retrospective cohort study
Background: This study investigated the genetic etiology of abnormal fetal fluid accumulation, aiming to quantify pathogenic variants and correlate them with clinical outcomes to improve genetic counseling. Methods: A cohort of 305 fetuses underwent single-nucleotide polymorphism array (SNP-array)…
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Identification of GRB2 and GAB1 Coexpression as an Unfavorable Prognostic Factor for Hepatocellular Carcinoma by a Combination of Expression Profile and Network Analysis
Aim: To screen novel markers for hepatocellular carcinoma (HCC) by a combination of expression profile, interaction network analysis and clinical validation. Methods: HCC significant molecules which are differentially expressed or had genetic variations in HCC tissues were obtained from five…
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Hematological analysis of alpha-thalassemia: A single-center, retrospective clinical study
Objectives: To determine the optimal cutoffs of the three indicators (MCV, MCH and HbA2) for alpha-thalassemia screening and to evaluate the validity of these indicators in Fujian Province, China. Methods: We conducted a retrospective analysis on the results of specimens received from May 2016 to…
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Elevated Bile Acids in Newborns with Biliary Atresia (BA)
Biliary Atresia (BA), a result from inflammatory destruction of the intrahepatic and extrahepatic bile ducts, is a severe hepatobiliary disorder unique to infancy. Early diagnosis and Kasai operation greatly improve the outcome of BA patients, which encourages the development of early screening…
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Anti-Angiogenic Effect of Triptolide in Rheumatoid Arthritis by Targeting Angiogenic Cascade
Rheumatoid arthritis (RA) is characterized by a pre-vascular seriously inflammatory phase, followed by a vascular phase with high increase in vessel growth. Since angiogenesis has been considered as an essential event in perpetuating inflammatory and immune responses, as well as supporting pannus…
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Influence of operating speed, load and mileage on the lubricating performance of self-lubricating rolling linear guide
Self-lubricating rolling linear guides are widely used in precision instruments, industrial automation production lines, and other fields. The lubrication performance of rolling linear guide has a significant impact on their smooth operation and service life. This paper aims to investigate…
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Evaluation of prenatal genetic aberrations in fetuses with gallbladder abnormalities: A retrospective cohort study
Background: With the widespread application of chromosomal microarray analysis (CMA) in prenatal diagnosis, fetal gallbladder abnormalities have been found to be associated not only with chromosomal aneuploidies but also with certain syndromes caused by submicroscopic chromosomal structural…
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Metabolic-dysfunction associated steatotic liver disease-related diseases, cognition and dementia: A two-sample mendelian randomization study
Background: The results of current studies on metabolic-dysfunction associated steatotic liver disease (MASLD)-related diseases, cognition and dementia are inconsistent. This study aimed to elucidate the effects of MASLD-related diseases on cognition and dementia. Methods: By using…
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A Systems Biology-Based Approach to Uncovering the Molecular Mechanisms Underlying the Effects of Dragon's Blood Tablet in Colitis, Involving the Integration of Chemical Analysis, ADME Prediction, and Network Pharmacology
Traditional Chinese medicine (TCM) is one of the oldest East Asian medical systems. The present study adopted a systems biology-based approach to provide new insights relating to the active constituents and molecular mechanisms underlying the effects of dragon's blood (DB) tablets for the treatment…
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Identification and Functional Analysis of Variant Haplotypes in the 5′-Flanking Region of Protein Phosphatase 2A-Bδ Gene
Serine-threonine protein phosphatase 2A (PP2A) is a trimeric holoenzyme that plays an integral role in the regulation of cell growth, differentiation, and apoptosis. The substrate specificity and (sub)cellular localization of the PP2A holoenzymes are highly regulated by interaction with a family of…
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Role of a Novel Functional Variant in the PPP2R1A Promoter on the Regulation of PP2A-Aalpha and the Risk of Hepatocellular Carcinoma
Previously, we identified the genetic variant −241 (−/G) (rs11453459) in the PP2A-Aα gene (PPP2R1A) promoter and demonstrated that this variant influences the DNA-binding affinity of nuclear factor-kappa B (NF-κB). In this study, we further confirmed that the transcriptional activity of PPP2R1A may…