6 hasil untuk "Nagarjun"

Dual DNA binding mode of a turn-on red fluorescent probe thiazole coumarin

Sudakshina Ganguly; Debasis Ghosh; Nagarjun Narayanaswamy dkk.

PLOS ONE, Vol. 15 No. 9 · 2020 · Inggris · PLOS Scopus

Turn-on fluorescent probes show enhanced emission upon DNA binding, advocating their importance in imaging cellular DNA. We have probed the DNA binding mode of thiazole-coumarin (TC) conjugate, a recently reported hemicyanine-based turn-on red fluorescent probe, using a number of biophysical…

Memory like NK cells display stem cell like properties after Zika virus infection

Weshely Kujur; Oscar Murillo; Raju S. R. Adduri dkk.

PLOS Pathogens, Vol. 16 No. 12 · 2020 · Inggris · PLOS Scopus

NK cells have been shown to display adaptive traits such as memory formation akin to T and B lymphocytes. Here we show that Zika virus infection induces memory like NK cells that express CD27. Strikingly, these cells exhibit stem-like features that include expansion capacity, self-renewal pathway…

Correction: Phosphatidylserine Targets Single-Walled Carbon Nanotubes to Professional Phagocytes In Vitro and In Vivo

Nagarjun V. Konduru; Yulia Y. Tyurina; Weihong Feng dkk.

PLoS ONE, Vol. 4 No. 5 · 2009 · Inggris · PLOS Scopus

Phosphatidylserine Targets Single-Walled Carbon Nanotubes to Professional Phagocytes In Vitro and In Vivo

Nagarjun V. Konduru; Yulia Y. Tyurina; Weihong Feng dkk.

PLoS ONE, Vol. 4 No. 2 · 2009 · Inggris · PLOS Scopus

Broad applications of single-walled carbon nanotubes (SWCNT) dictate the necessity to better understand their health effects. Poor recognition of non-functionalized SWCNT by phagocytes is prohibitive towards controlling their biological action. We report that SWCNT coating with a phospholipid…

Evaluation of ex vivo drug combination optimization platform in recurrent high grade astrocytic glioma: An interventional, non-randomized, open-label trial protocol

Tan Boon Toh; Dexter Kai Hao Thng; Nagarjun Bolem dkk.

PLOS ONE, Vol. 19 No. 7 · 2024 · Inggris · PLOS Scopus

Introduction: High grade astrocytic glioma (HGG) is a lethal solid malignancy with high recurrence rates and limited survival. While several cytotoxic agents have demonstrated efficacy against HGG, drug sensitivity testing platforms to aid in therapy selection are lacking. Patient-derived organoids…

Impaired Clearance and Enhanced Pulmonary Inflammatory/Fibrotic Response to Carbon Nanotubes in Myeloperoxidase-Deficient Mice

Anna A. Shvedova; Alexandr A. Kapralov; Wei Hong Feng dkk.

PLoS ONE, Vol. 7 No. 3 · 2012 · Inggris · PLOS Scopus

Advancement of biomedical applications of carbonaceous nanomaterials is hampered by their biopersistence and pro-inflammatory action in vivo. Here, we used myeloperoxidase knockout B6.129X1-MPO (MPO k/o) mice and showed that oxidation and clearance of single walled carbon nanotubes (SWCNT) from the…