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6 results for "Nancy R Cook"

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  1. Journal Article Full text

    Inflammation, Cholesterol, Lipoprotein(a), and 30-Year Cardiovascular Outcomes in Women

    Paul M. Ridker; M. Vinayaga Moorthy; Nancy R. Cook et al.

    New England Journal of Medicine · 2024 · English · OpenAlex Scopus

    BACKGROUND: High-sensitivity C-reactive protein (CRP), low-density lipoprotein (LDL) cholesterol, and lipoprotein(a) levels contribute to 5-year and 10-year predictions of cardiovascular risk and represent distinct pathways for pharmacologic intervention. More information about the usefulness of…

  2. Journal Article Full text

    Vitamin D and marine omega 3 fatty acid supplementation and incident autoimmune disease: VITAL randomized controlled trial

    Jill Hahn; Nancy R. Cook; Erik Karl Alexander et al.

    BMJ · 2022 · English · OpenAlex Scopus

    OBJECTIVE: To investigate whether vitamin D and marine derived long chain omega 3 fatty acids reduce autoimmune disease risk. DESIGN: Vitamin D and omega 3 trial (VITAL), a nationwide, randomized, double blind, placebo controlled trial with a two-by-two factorial design. SETTING: Nationwide in the…

  3. Journal Article Full text

    Effect of Vitamin D 3 Supplements on Development of Advanced Cancer

    Paulette D. Chandler; Wendy Y. Chen; Oluremi N Ajala et al.

    JAMA Network Open · 2020 · English · OpenAlex Scopus

    Importance: Epidemiologic and trial data suggest that vitamin D supplementation may reduce metastatic cancer and cancer mortality, reflecting shared biological pathways. Objective: To follow up on the possible reduction in cancer death in the Vitamin D and Omega-3 Trial (VITAL) with an evaluation…

  4. Journal Article Full text

    24-Hour Urinary Sodium and Potassium Excretion and Cardiovascular Risk

    Yuan Ma; Feng J. He; Qi Sun et al.

    New England Journal of Medicine · 2021 · English · OpenAlex Scopus

    BACKGROUND: The relation between sodium intake and cardiovascular disease remains controversial, owing in part to inaccurate assessment of sodium intake. Assessing 24-hour urinary excretion over a period of multiple days is considered to be an accurate method. METHODS: We included…

  5. Journal Article Full text

    SCORE2 risk prediction algorithms: new models to estimate 10-year risk of cardiovascular disease in Europe

    Steven H J Hageman; Lisa A M Pennells; Francisco Ojeda et al.

    European Heart Journal · 2021 · English · OpenAlex Scopus

    AIMS: The aim of this study was to develop, validate, and illustrate an updated prediction model (SCORE2) to estimate 10-year fatal and non-fatal cardiovascular disease (CVD) risk in individuals without previous CVD or diabetes aged 40-69 years in Europe. METHODS AND RESULTS: We derived risk…