4 hasil untuk "Philippe Mathurin"
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Artikel Jurnal Teks lengkap
Early prediction of the impact of public health policies on obesity and lifetime risk of type 2 diabetes: A modelling approach
Objective: Help public health decision-making requires a better understanding of the dynamics of obesity and type 2 diabetes and an assessement of different strategies to decrease their burdens. Methods: Based on 97,848 individual data, collected in the French Health, Health Care and Insurance…
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Artikel Jurnal Teks lengkap
Quality of life in patients with chronic hepatitis C infection: Severe comorbidities and disease perception matter more than liver-disease stage
Background and aims: This study evaluated the clinical and non-clinical determinants of health-related quality of life (HRQoL) associated with untreated chronic hepatitis C (CHC) in France. Methods: From 01/2014 to 01/2015, untreated CHC patients were invited to complete a questionnaire including…
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Artikel Jurnal Teks lengkap
Performance of Biomarkers FibroTest, ActiTest, SteatoTest, and NashTest in Patients with Severe Obesity: Meta Analysis of Individual Patient Data
Background: Liver biopsy is considered as the gold standard for assessing non-alcoholic fatty liver disease (NAFLD) histologic lesions in patients with severe obesity. The aim of this study was to perform an overview of 3 studies which assessed the performance of non-invasive markers of fibrosis…
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Artikel Jurnal Teks lengkap
A Proof of Concept, Phase II Randomized European Trial, on the Efficacy of ALF-5755, a Novel Extracellular Matrix-Targeted Antioxidant in Patients with Acute Liver Diseases
Objective: No efficient medical treatment is available for severe acute hepatitis (SAH) except N-acetylcysteine for acetaminophen-induced acute liver failure. The human C-type lectin Reg3α, referred to as ALF-5755, improved survival in an animal model of acute liver failure and was well tolerated…