1 results for "Prashanth, Kumar"

Targeted Apoptotic Effects of Thymoquinone and Tamoxifen on XIAP Mediated Akt Regulation in Breast Cancer

Shashi Rajput; B. N. Prashanth Kumar; Siddik Sarkar et al.

PLoS ONE, Vol. 8 No. 4 · 2013 · English · PLOS Scopus

X-linked inhibitor of apoptosis protein (XIAP) is constitutively expressed endogenous inhibitor of apoptosis, exhibit its antiapoptotic effect by inactivating key caspases such as caspase-3, caspase-7 and caspase-9 and also play pivotal role in rendering cancer chemoresistance. Our studies showed…