6 hasil untuk "RAVINA"
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Artikel Jurnal Teks lengkap
Biosignatures for Parkinson’s Disease and Atypical Parkinsonian Disorders Patients
Diagnosis of Parkinson’ disease (PD) carries a high misdiagnosis rate due to failure to recognize atypical parkinsonian disorders (APD). Usually by the time of diagnosis greater than 60% of the neurons in the substantia nigra are dead. Therefore, early detection would be beneficial so that…
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Structural and Ultrastructural Alterations in Human Olfactory Pathways and Possible Associations with Herpesvirus 6 Infection
Structural and ultrastructural alterations in human olfactory pathways and putative associations with human herpesvirus 6 (HHV-6) infection were studied. The olfactory bulb/tract samples from 20 subjects with an unspecified encephalopathy determined by pathomorphological examination of the brain…
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Artikel Jurnal Teks lengkap
The Voltage-Gated Sodium Channel Na v 1.8 Is Expressed in Human Sperm
The role of Na+ fluxes through voltage-gated sodium channels in the regulation of sperm cell function remains poorly understood. Previously, we reported that several genes encoding voltage-gated Na+ channels were expressed in human testis and mature spermatozoa. In this study, we analyzed the…
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Artikel Jurnal Teks lengkap
A Bayesian mathematical model of motor and cognitive outcomes in Parkinson’s disease
Background: There are few established predictors of the clinical course of PD. Prognostic markers would be useful for clinical care and research. Objective: To identify predictors of long-term motor and cognitive outcomes and rate of progression in PD. Methods: Newly diagnosed PD participants were…
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Artikel Jurnal Teks lengkap
Discovery of novel brain permeable and G protein-biased beta-1 adrenergic receptor partial agonists for the treatment of neurocognitive disorders
The beta-1 adrenergic receptor (ADRB1) is a promising therapeutic target intrinsically involved in the cognitive deficits and pathological features associated with Alzheimer’s disease (AD). Evidence indicates that ADRB1 plays an important role in regulating neuroinflammatory processes, and…
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Artikel Jurnal Teks lengkap
Clinical characteristics and outcomes of patients with Corona Virus Disease 2019 (COVID-19) at Mercy Health Hospitals, Toledo, Ohio
Importance: The ongoing pandemic of the novel Corona Virus Disease 2019 (COVID-19) is an unprecedented challenge to global health, never experienced before. Objective: This study aims to describe the clinical characteristics and outcomes of patients with COVID-19 admitted to Mercy Hospitals. Design…