2 hasil untuk "Rotem Fuchs"
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Artikel Jurnal
Evolutionary analysis of ZAP and its cofactors identifies intrinsically disordered regions as central elements in host-pathogen interactions
The zinc-finger antiviral protein (ZAP) is an innate immunity sensor of non-self nucleic acids. Its antiviral activity is exerted through the physical interaction with different cofactors, including TRIM25, Riplet and KHNYN. Cellular proteins that interact with infectious agents are expected to be…
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Artikel Jurnal
The evolutionary dynamics between viral mimics and host proteins
Abstract Viral proteins interact with host proteins to hijack cellular pathways important for viral replication. Viral mimics are proteins whose structural similarity to host-mimicked proteins allows them to interact with mutual host targets. This mimicry poses a challenge for the host—how to avoid…