5 hasil untuk "Samiran Ray"
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Artikel Jurnal Teks lengkap
Arterial carboxyhaemoglobin levels in children admitted to PICU: A retrospective observational study
While carbon monoxide (CO) is considered toxic, low levels of endogenously produced CO are protective against cellular injury induced by oxidative stress. Carboxyhaemoglobin (COHb) levels have been associated with outcomes in critically ill adults. We aimed to describe the distribution of…
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Artikel Jurnal Teks lengkap
A physiologically constrained calibration framework for cardiovascular models applied to a paediatric synthetic sepsis population
Calibration of mechanistic cardiovascular models is a central barrier to their use in population analysis and patient-specific simulation, particularly in settings where key physiological variables are unobservable and multiple parameter combinations can reproduce the same haemodynamic targets. In…
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Artikel Jurnal Teks lengkap
Transitions in intensive care: Investigating critical slowing down post extubation
Complex biological systems undergo sudden transitions in their state, which are often preceded by a critical slowing down of dynamics. This results in longer recovery times as systems approach transitions, quantified as an increase in measures such as the autocorrelation and variance. In this…
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Artikel Jurnal Teks lengkap
Improved oxygenation following methylprednisolone therapy and survival in paediatric acute respiratory distress syndrome
Background: Methylprednisolone remains a commonly used ancillary therapy for paediatric acute respiratory distress syndrome (PARDS), despite a lack of level 1 evidence to justify its use. When planning prospective trials it is useful to define response to therapy and to identify if there is…
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Artikel Jurnal Teks lengkap
The Predictive Value of the NICE “Red Traffic Lights” in Acutely Ill Children
Objective: Early recognition and treatment of febrile children with serious infections (SI) improves prognosis, however, early detection can be difficult. We aimed to validate the predictive rule-in value of the National Institute for Health and Clinical Excellence (NICE) most severe alarming signs…