1 hasil untuk "Sarah Stephan"

Alpha Therapy Beyond TOC and TATE—Production, Quality Control, and In-Human Results for the SSTR2 Antagonist DOTA-LM3

Lukas Greifenstein; Marcel Martin; Sarah Stephan dkk.

Pharmaceuticals, Vol. 19 No. 1 · 2026 · Inggris · DOAJ Scopus

Objectives: Peptide receptor radionuclide therapy (PRRT) of neuroendocrine tumors (NETs) commonly relies on somatostatin receptor subtype 2 (SSTR2) agonists such as DOTA-TOC/TATE, which may show limited efficacy due to high hepatic uptake and therapy resistance in some patients. SSTR2 antagonists…