1 results for "Servius"

Characterizing inhibitors of human AP endonuclease 1

Lakshmi S. Pidugu; Hardler W. Servius; Spiridon E. Sevdalis et al.

PLOS ONE, Vol. 18 No. 1 · 2023 · English · PLOS Scopus

AP endonuclease 1 (APE1) processes DNA lesions including apurinic/apyrimidinic sites and 3´-blocking groups, mediating base excision repair and single strand break repair. Much effort has focused on developing specific inhibitors of APE1, which could have important applications in basic research…