244 hasil untuk "Shabbir Muhammad"
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Complete Genome Sequence Analysis of a Vaccine Strain of Foot-and-Mouth Disease Virus Serotype O from Pakistan
Sequencing and subsequent analysis of a vaccine strain of foot-and-mouth disease virus serotype O is reported here. Genomic heterogeneity in the protective epitopes (VP1 protein) of the reported strain, compared to characterized strains and available sequences from Pakistan, warrants further…
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Myxomatous tumours of the right atrium in a patient with recurring myasthenia gravis exacerbations
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Iatrogenic coronary artery perforation resulting in intramyocardial haematoma and ventricular pseudoaneurysm
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Two-fluid flow of blood in a curved stenotic artery under pulsating condition
The present article focuses on the analysis of the two-phase flow of blood via a stenosed artery under the influence of a pulsatile pressure gradient. The core and plasma regions of flow are modeled using the constitutive relations of Herschel-Bulkley and the Newtonian fluids, respectively. The…
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Electromagnetohydrodynamic flow of fractional Maxwell fluids through a stenosed artery: Caputo fractional derivatives approach
This study investigates the electromagnetohydrodynamic (EMHD) flow of fractional Maxwell fluids through a stenosed artery, accounting for body acceleration. The flow is considered highly pulsatile. The mathematical model is formulated using differential forms of the conservation of mass and…
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Bacteria vs. Bacteriophages: Parallel Evolution of Immune Arsenals
Bacteriophages are the most common entities on earth and represent a constant challenge to bacterial populations. To fend off bacteriophage infection, bacteria evolved immune systems to avert phage adsorption and block invader DNA entry. They developed restriction–modification systems and…
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Plasmonically enhanced mid-IR light source based on tunable spectrally and directionally selective thermal emission from nanopatterned graphene
We present a proof of concept for a spectrally selective thermal mid-IR source based on nanopatterned graphene (NPG) with a typical mobility of CVD-grown graphene (up to 3000 [Formula: see text] ), ensuring scalability to large areas. For that, we solve the electrostatic problem of a conducting…
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Impact of Age on Mortality and Decompensation Events in Patients With Liver Cirrhosis: A Multicenter, Propensity Score Matched Study
BACKGROUND: The incidence of cirrhosis is increasing in the older population. Limited data are available on the disease progression and mortality in the older population with cirrhosis. This study is aimed at evaluating the impact of age at diagnosis on all-cause mortality and decompensation events…
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Genetic analysis of peste des petits ruminants virus from Pakistan
BACKGROUND: Peste des petits ruminants (PPR) is an endemic and highly contagious disease in small ruminants of Pakistan. Despite the fact that an effective vaccine is available, outbreaks are regularly occurring in the country. Thus so far, the diagnosis has primarily been made based on clinical…
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Complete Genome Sequence of a Velogenic Neurotropic Avian Paramyxovirus 1 Isolated from Peacocks (Pavo cristatus) in a Wildlife Park in Pakistan
Avian paramyxovirus serotype 1 (APMV-1) was isolated from an acute and highly contagious outbreak in peacocks (Pavo cristatus) in a wildlife park in Pakistan. A velogenic neurotropic form of APMV-1 caused a 100% case fatality rate and killed 190 peacocks within a week. Biological and serological…
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Application of Artificial Intelligence powered digital writing assistant in higher education: randomized controlled trial
A major challenge in educational technology integration is to engage students with different affective characteristics. Also, how technology shapes attitude and learning behavior is still lacking. Findings from educational psychology and learning sciences have gained less traction in research. The…
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A case report of non-dominant right coronary artery occlusion: not always benign!
BACKGROUND: Non-dominant right coronary artery (RCA) occlusion is uncommon and usually affects a small area of the myocardium. Rarely, it can complicate fatal outcomes such as shock, cardiac arrest, bradyarrhythmia, or tachyarrhythmia. CASE SUMMARY: A 50-year-old man with no significant medical…
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Complete Genome Sequencing of a Velogenic Viscerotropic Avian Paramyxovirus 1 Isolated from Pheasants (Pucrasia macrolopha) in Lahore, Pakistan
We report the complete genome sequence of avian paramyxovirus 1 (APMV-1) isolated from an acute and highly contagious outbreak in pheasants (Pucrasia macrolopha) in Lahore, Pakistan. Biological and serological characterization showed a velogenic strain of APMV-1, which was further confirmed by the…
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A comparative phylogenomic analysis of SARS-CoV-2 strains reported from non-human mammalian species and environmental samples
Coronaviruses (CoVs) infect a wide range of domestic and wild mammals. These viruses have a potential and tendency to cross-species barriers and infect humans. Novel human coronavirus 2019-nCoV (hCoV-19) emerged from Wuhan, China, and has caused a global pandemic. Genomic features of SARS-CoV-2 may…
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Adaptation of Newcastle Disease Virus (NDV) in Feral Birds and their Potential Role in Interspecies Transmission
INTRODUCTION: Newcastle Disease (ND), caused by Avian avulavirus 1 (AAvV 1, avulaviruses), is a notifiable disease throughout the world due to the economic impact on trading restrictions and its embargoes placed in endemic regions. The feral birds including aquatic/migratory birds and other wild…
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A comprehensive global perspective on phylogenomics and evolutionary dynamics of Small ruminant morbillivirus
A string of complete genome sequences of Small ruminant morbillivirus (SRMV) have been reported from different parts of the globe including Asia, Africa and the Middle East. Despite individual genome sequence-based analysis, there is a paucity of comparative genomic and evolutionary analysis to…
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Microbial communities present in the lower respiratory tract of clinically healthy birds in Pakistan
Commercial poultry is an important agricultural industry worldwide. Although dense living conditions and large flocks increase meat and egg production, they also increase the risk of disease outbreaks and zoonoses. Current pathogen identification methods mostly rely on culture-dependent techniques…
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Transcriptome and Proteome Alternation With Resistance to Bacillus thuringiensis Cry1Ah Toxin in Ostrinia furnacalis
Background: Asian corn borer (ACB), Ostrinia furnacalis can develop resistance to transgenic Bacillus thuringiensis (Bt) maize expressing Cry1Ah-toxin. However, the mechanisms that regulate the resistance of ACB to Cry1Ah-toxin are unknown. Objective: In order to understand the molecular basis of…
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Plasmablastic Lymphoma Mimicking Osteomyelitis of Femur in an Immunocompetent Individual: A Case Report
Plasmablastic lymphoma (PBL) is an aggressive type of diffuse large B-cell lymphoma. It is most commonly seen in patients with human immunodeficiency virus (HIV) infection and other immunodeficiencies manifesting commonly in the form of oral lesions. Here, we report a case of an HIV-negative…