11 hasil untuk "Shin-Yu Lin"

The Safety and Immunogenicity of Trivalent Inactivated Influenza Vaccination: A Study of Maternal-Cord Blood Pairs in Taiwan

Shin-Yu Lin; En-Tzu Wu; Chia-Hui Lin dkk.

PLoS ONE, Vol. 8 No. 6 · 2013 · Inggris · PLOS Scopus

Background: There are little data about adverse effects and immunogenicity of flu vaccine in Asian pregnant women. Methods: This prospective trial (NCT01514708) enrolled 46 pregnant women who received a single intramuscular dose of trivalent flu vaccine (AdimFlu-S®) containing 15 mcg of…

Tentative Identification of the Second Substrate Binding Site in Arabidopsis Phytochelatin Synthase

Ju-Chen Chia; Chien-Chih Yang; Yu-Ting Sui dkk.

PLoS ONE, Vol. 8 No. 12 · 2013 · Inggris · PLOS Scopus

Phytochelatin synthase (PCS) uses the substrates glutathione (GSH, γGlu-Cys-Gly) and a cadmium (Cd)-bound GSH (Cd∙GS2) to produce the shortest phytochelatin product (PC2, (γGlu-Cys)2-Gly) through a ping-pong mechanism. The binding of the 2 substrates to the active site, particularly the second…

New ultrasound grading system for cesarean scar pregnancy and its implications for management strategies: An observational cohort study

Shin-Yu Lin; Chia-Jung Hsieh; Yi-An Tu dkk.

PLOS ONE, Vol. 13 No. 8 · 2018 · Inggris · PLOS Scopus

A cesarean section pregnancy (CSP) indicated the gestational sac (GS) implanted in the previous cesarean scar. The clinical manifestations of CSP present a wide range of variations, and the optimal management is yet to be defined. We retrospectively enrolled 109 patients with the diagnosis of CSP…

Simplifying the screening of gestational diabetes by maternal age plus fasting plasma glucose at first prenatal visit: A prospective cohort study

Yi-Yun Tai; Chien-Nan Lee; Chun-Heng Kuo dkk.

PLOS ONE, Vol. 15 No. 8 · 2020 · Inggris · PLOS Scopus

Aim: The addition of maternal age to fasting plasma glucose (FPG) at 24–28 gestational weeks improves the performance of GDM screening as maternal age increases. However, this method delays the diagnosis of GDM. Since FPG at the first prenatal visit (FPV) is a screening option for pre-existing…

The Impact of Down Syndrome Screening on Taiwanese Down Syndrome Births: A Nationwide Retrospective Study and a Screening Result from a Single Medical Centre

Shin-Yu Lin; Chia-Jung Hsieh; Yi-Li Chen dkk.

PLoS ONE, Vol. 8 No. 9 · 2013 · Inggris · PLOS Scopus

A retrospective analysis of the Taiwanese National Birth Defect Registration and Notification System was conducted in order to determine the live birth- and stillbirth rates in infants with Down syndrome, trisomy 18, trisomy 13 and Turner syndrome between 2001 and 2010. The objective was to…

Correction: The Impact of Down Syndrome Screening on Taiwanese Down Syndrome Births: A Nationwide Retrospective Study and a Screening Result from a Single Medical Centre

Shin-Yu Lin; Chia-Jung Hsieh; Yi-Li Chen dkk.

PLoS ONE, Vol. 8 No. 12 · 2013 · Inggris · PLOS Scopus

Newborn Genetic Screening for Hearing Impairment: A Preliminary Study at a Tertiary Center

Chen-Chi Wu; Chia-Cheng Hung; Shin-Yu Lin dkk.

PLoS ONE, Vol. 6 No. 7 · 2011 · Inggris · PLOS Scopus

Universal newborn hearing screening (UNHS) is of paramount importance for early identification and management of hearing impairment in children. However, infants with slight/mild, progressive, or late-onset hearing impairment might be missed in conventional UNHS. To investigate whether genetic…

Targeted fetal NGS panel reveals genetic conditions in sonographically normal fetuses: Insights from a large cohort study

Han-Ying Chen; Yi-Ting Wang; Jessica Kang dkk.

PLOS One, Vol. 20 No. 12 · 2025 · Inggris · PLOS Scopus

Prenatal genetic testing plays a crucial role in prenatal diagnosis and is traditionally performed when abnormalities are detected on fetal ultrasound. With the widespread availability of next-generation sequencing (NGS), genetic screening is increasingly being applied to fetuses with normal…

Screening gestational diabetes mellitus: The role of maternal age

Chun-Heng Kuo; Szu-Chi Chen; Chi-Tai Fang dkk.

PLOS ONE, Vol. 12 No. 3 · 2017 · Inggris · PLOS Scopus

Objective: Using a specific cutoff of fasting plasma glucose (FPG) to screen gestational diabetes mellitus (GDM) can reduce the use of oral glucose tolerance tests (OGTT). Since the prevalence of GDM increases with age, this screening method may not be appropriate in healthcare systems where women…

Carrier Screening for Spinal Muscular Atrophy (SMA) in 107,611 Pregnant Women during the Period 2005–2009: A Prospective Population-Based Cohort Study

Yi-Ning Su; Chia-Cheng Hung; Shin-Yu Lin dkk.

PLoS ONE, Vol. 6 No. 2 · 2011 · Inggris · PLOS Scopus

Background: Spinal muscular atrophy (SMA) is the most common neuromuscular autosomal recessive disorder. The American College of Medical Genetics has recently recommended routine carrier screening for SMA because of the high carrier frequency (1 in 25–50) as well as the severity of that genetic…

Overweight and obesity are associated with clustering of metabolic risk factors in early pregnancy and the risk of GDM

I-Weng Yen; Chien-Nan Lee; Ming-Wei Lin dkk.

PLOS ONE, Vol. 14 No. 12 · 2019 · Inggris · PLOS Scopus

Aim: Overweight and obesity are important risk factors of gestational diabetes mellitus (GDM). Clustering of metabolic risk factors in early pregnancy may be a potential pathogenesis between the link of overweight/obesity and GDM. Since it remains unexplored, we investigated if overweight and…