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Predicting and comparing transcription start sites in single cell populations

Shiwei Fu; Wei Vivian Li

PLOS Computational Biology, Vol. 21 No. 4 · 2025 · Inggris · PLOS Scopus

The advent of 5’ single-cell RNA sequencing (scRNA-seq) technologies offers unique opportunities to identify and analyze transcription start sites (TSSs) at a single-cell resolution. These technologies have the potential to uncover the complexities of transcription initiation and alternative TSS…