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3 hasil untuk "Sikander Azam"

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  1. Artikel Jurnal Teks lengkap

    Deciphering the relational dynamics of AF-2 domain of PAN PPAR through drug repurposing and comparative simulations

    Fouzia Gul; Nousheen Parvaiz; Syed Sikander Azam

    PLOS ONE, Vol. 18 No. 3 · 2023 · Inggris · PLOS Scopus

    Peroxisome proliferator-activated receptors (PPARs) are nuclear receptors, and their activation has been proven to treat mild liver fibrosis, reduce steatosis, inflammation, and the extrahepatic effects of chronic liver disease. Considering the significance of the PPARs, it is targeted for the…

  2. Artikel Jurnal Teks lengkap

    Senna makki and other active phytochemicals: Myths and realities behind covid19 therapeutic interventions

    Naila Zaman; Nousheen Parvaiz; Rabia Farid dkk.

    PLOS ONE, Vol. 17 No. 6 · 2022 · Inggris · PLOS Scopus

    This study aims to investigate the binding potential of chemical compounds of Senna in comparison with the experimentally tested active phytochemicals against SARS-CoV-2 protein targets to assist in prevention of infection by exploring multiple treatment options. The entire set of phytochemicals…

  3. Artikel Jurnal Teks lengkap

    Discovery of beta-lactamase CMY-10 inhibitors for combination therapy against multi-drug resistant Enterobacteriaceae

    Nousheen Parvaiz; Faisal Ahmad; Wenbo Yu dkk.

    PLOS ONE, Vol. 16 No. 1 · 2021 · Inggris · PLOS Scopus

    β-lactam antibiotics are the most widely used antimicrobial agents since the discovery of benzylpenicillin in the 1920s. Unfortunately, these life-saving antibiotics are vulnerable to inactivation by continuously evolving β-lactamase enzymes that are primary resistance determinants in multi-drug…