4 hasil untuk "Simon Mathien"

Evaluation of a Novel Fluorescent Marker for Continuous Live Imaging of Preimplantation Embryos

Debbie Montjean; Karine Audette; Simon Mathien dkk.

Journal of Developmental Biology, Vol. 14 No. 3 · 2026 · Inggris · DOAJ Scopus

This study evaluates ChromaLIVETM, a multichromatic, mix-and-read fluorescent marker developed for continuous live-cell imaging, in the context of embryology. The aim was to evaluate whether this marker is compatible with dynamic embryonic development up to the blastocyst stage, with minimal impact…

Live cell painting: New nontoxic dye to probe cell physiology in high content screening

Martin Cottet; Yuniel Fernandez Marrero; Simon Mathien dkk.

SLAS Discovery, Vol. 29 No. 3 · 2024 · Inggris · DOAJ Scopus

High-content imaging approaches, in combination with the use of perturbing agents such as small molecules or CRISPR-driven gene editing, have widely contributed to the identification of new therapeutic compounds. Thanks to recent advances in image-analysis methods, the use of high-content screens…

The Non-Classical MAP Kinase ERK3 Controls T Cell Activation

Miriam Marquis; Salix Boulet; Simon Mathien dkk.

PLoS ONE, Vol. 9 No. 1 · 2014 · Inggris · PLOS Scopus

The classical mitogen-activated protein kinases (MAPKs) ERK1 and ERK2 are activated upon stimulation of cells with a broad range of extracellular signals (including antigens) allowing cellular responses to occur. ERK3 is an atypical member of the MAPK family with highest homology to ERK1/2…

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