1 results for "Simone Altmann"

Acoziborole resistance associated mutations in Trypanosoma brucei CPSF3

Melanie Ridgway; Markéta Novotná; Cesar Mendoza-Martinez et al.

PLOS Pathogens, Vol. 22 No. 3 · 2026 · English · PLOS Scopus

Acoziborole is a safe, single dose, oral therapy, for treatment of both early and late-stage sleeping sickness, a deadly disease caused by African trypanosomes. Other benzoxaboroles show efficacy against other trypanosomatids, apicomplexans, fungi, bacteria, and viruses. Acoziborole targets the…