1 results for "Simone Wendlinger"

Inhibition of p90 ribosomal S6 kinases disrupts melanoma cell growth and immune evasion

Corinna Kosnopfel; Simone Wendlinger; Heike Niessner et al.

Journal of Experimental & Clinical Cancer Research, Vol. 42 No. 1 · 2023 · English · DOAJ Scopus

Abstract Background The mitogen-activated protein kinase (MAPK) signaling pathway is frequently hyperactivated in malignant melanoma and its inhibition has proved to be an efficient treatment option for cases harboring BRAFV600 mutations (BRAFMut). However, there is still a significant need for…