7 hasil untuk "Stephan Ellmann"

Multiparametric magnetic resonance imaging of experimental chronic kidney disease: A quantitative correlation study with histology

Gunnar Schley; Jutta Jordan; Stephan Ellmann dkk.

PLOS ONE, Vol. 13 No. 7 · 2018 · Inggris · PLOS Scopus

Objectives: In human chronic kidney disease (CKD) the extent of renal tubulointerstitial fibrosis correlates with progressive loss of renal function. However, fibrosis can so far only be assessed by histology of kidney biopsies. Magnetic resonance imaging (MRI) can provide information about tissue…

Correction: Multiparametric magnetic resonance imaging of experimental chronic kidney disease: A quantitative correlation study with histology

Gunnar Schley; Jutta Jordan; Stephan Ellmann dkk.

PLOS ONE, Vol. 14 No. 6 · 2019 · Inggris · PLOS Scopus

Influence of Different Antioxidants on X-Ray Induced DNA Double-Strand Breaks (DSBs) Using γ-H2AX Immunofluorescence Microscopy in a Preliminary Study

Michael Brand; Matthias Sommer; Stephan Ellmann dkk.

PLOS ONE, Vol. 10 No. 5 · 2015 · Inggris · PLOS Scopus

Background: Radiation exposure occurs in X-ray guided interventional procedures or computed tomography (CT) and γ-H2AX-foci are recognized to represent DNA double-strand breaks (DSBs) as a biomarker for radiation induced damage. Antioxidants may reduce the induction of γ-H2AX-foci by binding free…

Application of machine learning algorithms for multiparametric MRI-based evaluation of murine colitis

Stephan Ellmann; Victoria Langer; Nathalie Britzen-Laurent dkk.

PLOS ONE, Vol. 13 No. 10 · 2018 · Inggris · PLOS Scopus

Magnetic resonance imaging (MRI) allows non-invasive evaluation of inflammatory bowel disease (IBD) by assessing pathologically altered gut. Besides morphological changes, relaxation times and diffusion capacity of involved bowel segments can be obtained by MRI. The aim of this study was to assess…

ADP Ribosylation by PARP-1 Suppresses HOXB7 Transcriptional Activity

Xinyan Wu; Stephan Ellmann; Ethel Rubin dkk.

PLoS ONE, Vol. 7 No. 7 · 2012 · Inggris · PLOS Scopus

Interactions with cofactors regulate transcriptional activity and also help HOX proteins to achieve the specificity required for transcriptional regulation of target genes. In this study, we describe a novel protein/protein interaction of HOXB7 with poly (ADP-ribose) polymerase-1 (PARP-1) that…

Implementation of machine learning into clinical breast MRI: Potential for objective and accurate decision-making in suspicious breast masses

Stephan Ellmann; Evelyn Wenkel; Matthias Dietzel dkk.

PLOS ONE, Vol. 15 No. 1 · 2020 · Inggris · PLOS Scopus

We investigated whether the integration of machine learning (ML) into MRI interpretation can provide accurate decision rules for the management of suspicious breast masses. A total of 173 consecutive patients with suspicious breast masses upon complementary assessment (BI-RADS IV/V: n = 100/76)…

How COVID-19 kick-started online learning in medical education—The DigiMed study

Fabian Stoehr; Lukas Müller; Adrian Brady dkk.

PLOS ONE, Vol. 16 No. 9 · 2021 · Inggris · PLOS Scopus

Background: The coronavirus disease 2019 (COVID-19) pandemic led to far-reaching restrictions of social and professional life, affecting societies all over the world. To contain the virus, medical schools had to restructure their curriculum by switching to online learning. However, only few medical…