10 hasil untuk "Sun, Li-Sha"
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Artikel Jurnal Teks lengkap
Identification of Known and Novel PTCH Mutations in Both Syndromic and Non-syndromic Keratocystic Odontogenic Tumors
AIM: To clarify the role of PTCH in patients with NBCCS-related and non-sydromic keratocystic odontogenic tumors. METHODOLOGY: Mutation analysis was undertaken in 8 sporadic and 4 NBCCS-associated KCOTs. RESULTS: Four novel and two known mutations were identified in 2 sporadic and 3 syndromic…
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Artikel Jurnal Teks lengkap
Can botulinum toxin injection alleviate the pain of bruxism? A Bayesian network analysis and a single-arm analysis
BACKGROUND/PURPOSE: There is inconsistent evidence regarding whether the botulinum toxin A (BTA) injection can relieve pain caused by bruxism. This study aimed to estimate the efficiency of BTA injection in relieving pain caused by bruxism at different follow-up periods. MATERIALS AND METHODS: Five…
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Artikel Jurnal Teks lengkap
Association of IL-8 gene promoter −251 A/T and IL-18 gene promoter −137 G/C polymorphisms with head and neck cancer risk: a comprehensive meta-analysis
PURPOSE: No consensus exists on the impact of polymorphisms in cytokines (such as interleukin IL-8 and IL-18) on cancer risk; moreover, there is very little evidence regarding head and neck cancer (HNC). METHODS: Thus, a meta-analysis including 22 studies with 4731 cases and 8736 controls was…
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Artikel Jurnal Teks lengkap
Identification of the involvement of LOXL4 in generation of keratocystic odontogenic tumors by RNA-Seq analysis
Keratocystic odontogenic tumors (KCOT) are benign, locally aggressive intraosseous tumors of odontogenic origin. KCOT have a higher stromal microvessel density (MVD) than dentigerous cysts (DC) and normal oral mucosa. To identify genes in the stroma of KCOT involved in tumor development and…
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Artikel Jurnal Teks lengkap
miR-762 Promotes Malignant Development of Head and Neck Squamous Cell Carcinoma by Targeting PHLPP2 and FOXO4
BACKGROUND: Head and neck squamous cell carcinoma (HNSCC) is among the most common malignant tumors worldwide. This study, investigated the role of microRNA (miR)-762 in regulating HNSCC progression. MATERIALS AND METHODS: The expression levels of miR-762 in HNSCC tissues were measured by…
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Artikel Jurnal Teks lengkap
HTRA3 Is a Prognostic Biomarker and Associated With Immune Infiltrates in Gastric Cancer
HtrA serine peptidase 3 (HTRA3) participates in multiple signal pathways and plays an important regulatory role in various malignancies; however, its role on prognosis and immune infiltrates in gastric cancer (GC) remains unclear. The study investigated HTRA3 expression in tumor tissues and its…
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Circ_0068087 knockdown attenuates high‐glucose‐induced human tubular epithelial cell injury in a microribonucleic acid/progestin and adipoQ receptor 3‐dependent manner in diabetic nephropathy
AIMS/INTRODUCTION: Previous studies have shown that circular ribonucleic acid mediates the occurrence of diabetic nephropathy. This study aimed to analyze the effects of circ_0068087 on high‐glucose (HG)‐induced human kidney 2 (HK2) cell dysfunction. MATERIALS AND METHODS: Circ_0068087, miR‐580‐3p…
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Artikel Jurnal Teks lengkap
The prevalence, diagnostic accuracy and genotype-phenotype correlation of GNAS mutations in fibrous dysplasia: a meta-analysis
BACKGROUND: There is inconsistent evidence regarding the accuracy of GNAS mutations identification for the diagnosis of FD/MAS. This study was performed to estimate the prevalence and diagnostic accuracy of GNAS mutations detection and to preliminarily investigate the genotype-phenotype correlation…
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Artikel Jurnal Teks lengkap
Increased Cerebrospinal Fluid Uric Acid Levels in Guillain–Barré Syndrome
Uric acid (UA) is a natural scavenger for peroxynitrite and can reflect antioxidant activity and oxidative stress in several neurological disorders. Changes in serum and cerebrospinal fluid (CSF) levels of UA have been reported in patients with multiple sclerosis and neuromyelitis optica spectrum…
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Artikel Jurnal Teks lengkap
Oncogenic EGFR Represses the TET1 DNA Demethylase to Induce Silencing of Tumor Suppressors in Cancer Cells
Oncogene-induced DNA methylation-mediated transcriptional silencing of tumor suppressors frequently occurs in cancer, but the mechanism and functional role of this silencing in oncogenesis is not fully understood. Here, we show that oncogenic epidermal growth factor receptor (EGFR) induces…