1 hasil untuk "Syed Muhammad Saad"

Thymidine phosphorylase and prostrate cancer cell proliferation inhibitory activities of synthetic 4-hydroxybenzohydrazides: In vitro , kinetic, and in silico studies

Sumaira Javaid; Syed Muhammad Saad; Humaira Zafar dkk.

PLOS ONE, Vol. 15 No. 1 · 2020 · Inggris · PLOS Scopus

Over-expression of thymidine phosphorylase (TP) plays a key role in many pathological complications, including angiogenesis which leads to cancer cells proliferation. Thus in search of new anticancer agents, a series of 4-hydroxybenzohydrazides (1–29) was synthesized, and evaluated for in vitro…