27 hasil untuk "Tang, Li-li"
Menampilkan 1–20 · 6,44 detik · RSS
-
Artikel Jurnal Teks lengkap
Clinical significance of androgen receptor expression in triple negative breast cancer-an immunohistochemistry study
Androgen receptor (AR) is closely associated with the occurrence and progression of breast cancer; however, the clinical significance of it in triple negative breast cancer (TNBC) has been controversial. There is a limited amount of research regarding the effect of neoadjuvant chemotherapy on AR…
-
Artikel Jurnal Teks lengkap
Does public pension crowd out the participation of older adults in community volunteering? Evidence from China
BACKGROUND: To address aging and its associated social risks, the World Health Organization proposed an “active aging” policy framework in 2002, highlighting “health, participation, and security” as the three pillars for enhancing quality of life in old age. Extensive research has shown that public…
-
Artikel Jurnal Teks lengkap
Explainable models for predicting long-term outcomes in patients with spontaneous intracerebral haemorrhage: a retrospective cohort study
BACKGROUND AND AIM: Recently, long-term outcomes in patients with spontaneous intracerebral haemorrhage (sICH) have gained increasing attention besides acute-phase characteristics. Predictive models for long-term outcomes are valuable for risk stratification and treatment strategies. This study…
-
Artikel Jurnal Teks lengkap
Validation And Reliability of Distress Thermometer in Chinese Cancer Patients
OBJECTIVE: To examine the validation and reliability of the distress thermometer (DT) recommended by National Comprehensive Cancer Network (NCCN) in Chinese cancer patients. METHODS: A total of 574 Chinese cancer patients from Beijing Cancer Hospital completed the detection of DT, the Hospital…
-
Artikel Jurnal Teks lengkap
ABNORMAL POLLEN TUBE GUIDANCE1, an Endoplasmic Reticulum-Localized Mannosyltransferase Homolog of GLYCOSYLPHOSPHATIDYLINOSITOL10 in Yeast and PHOSPHATIDYLINOSITOL GLYCAN ANCHOR BIOSYNTHESIS B in Human, Is Required for Arabidopsis Pollen Tube Micropylar Guidance and Embryo Development
The perception and response of pollen tubes to the female guidance signals are crucial for directional pollen tube growth inside female tissues, which leads to successful reproduction. In pursuing the mechanisms underlying this biological process, we identified the Arabidopsis (Arabidopsis…
-
Artikel Jurnal Teks lengkap
Associations between body mass index and molecular subtypes as well as other clinical characteristics of breast cancer in Chinese women
BACKGROUND: Several studies have shown a positive association between body mass index (BMI) and the development of hormone receptor-positive breast cancer in postmenopausal women; however, the associations between BMI groups and molecular subtypes have yet to be well defined in premenopausal breast…
-
Artikel Jurnal Teks lengkap
Epigenetics of hypoxic pulmonary arterial hypertension following intrauterine growth retardation rat: epigenetics in PAH following IUGR
BACKGROUND: Accumulating evidence reveals that intrauterine growth retardation (IUGR) can cause varying degrees of pulmonary arterial hypertension (PAH) later in life. Moreover, epigenetics plays an important role in the fetal origin of adult disease. The goal of this study was to investigate the…
Juga tersedia di: DOAJ
-
Artikel Jurnal Teks lengkap
Drooling disrupts the brain functional connectivity network in Parkinson's disease
AIMS: This study aimed to investigate the causal interaction between significant sensorimotor network (SMN) regions and other brain regions in Parkinson's disease patients with drooling (droolers). METHODS: Twenty‐one droolers, 22 PD patients without drooling (non‐droolers), and 22 matched healthy…
-
Artikel Jurnal Teks lengkap
Epigenetics of Notch1 regulation in pulmonary microvascular rarefaction following extrauterine growth restriction
BACKGROUND: Extrauterine growth restriction (EUGR) plays an important role in the developmental origin of adult cardiovascular diseases. In an EUGR rat model, we reported an elevated pulmonary arterial pressure in adults and genome-wide epigenetic modifications in pulmonary vascular endothelial…
-
Artikel Jurnal Teks lengkap
Internet Use and Depressive Symptoms Among Older Adults in China
This study investigated the effect of using the Internet on depression symptoms of older Chinese, based on 7,801 adults aged over 60 years from the 2018 China Family Panel Studies. Results showed that the elderly who used the Internet reported lower depression scores, and the more frequent they use…
-
Artikel Jurnal Teks lengkap
Effect of Working After Retirement on the Mental Health of Older People: Evidence From China
There is little empirical research on the effect of working after retirement on the mental health of the older adults in China. To fill this gap in the literature, this study examines the effects of working after retirement on the mental health of the older adults using data from the China Family…
-
Artikel Jurnal
Mutations and Down-Regulation of CDX1 in Children with Anorectal Malformations
Background: Anorectal malformations (ARMs) represent a variety of congenital disorders that involve abnormal termination of the anorectum. This study was to reveal relation between CDX1 and human ARMs phenotypes.Methods: 108 Chinese patients and 120 Chinese controls were included in this study. We…
-
Artikel Jurnal Teks lengkap
Epigenetics of hyper-responsiveness to allergen challenge following intrauterine growth retardation rat
BACKGROUND: Epidemiological studies have revealed that intrauterine growth retardation (IUGR) or low birth weight is linked to the later development of asthma. Epigenetic regulatory mechanisms play an important role in the fetal origins of adult disease. However, little is known regarding the…
-
Artikel Jurnal Teks lengkap
An infertile man with gynecomastia caused by a novel mutation of the androgen receptor gene
-
Artikel Jurnal Teks lengkap
Neuroprotective Effects and Related Mechanisms of Echinacoside in MPTP-Induced PD Mice
OBJECTIVE: To explore the neuroprotective effect and the related mechanisms of echinacoside (ECH) in 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP)-induced Parkinson’s disease (PD) mice. METHODS: Parkinson’s disease is induced in mice by MPTP and the neurobehaviors of mice in different groups…
-
Artikel Jurnal Teks lengkap
Mechanism of Autophagy Regulation in MPTP-Induced PD Mice via the mTOR Signaling Pathway by Echinacoside
OBJECTIVE: The present study aimed to investigate the effect of echinacoside on autophagy-related indicators through the mTOR signaling pathway, especially the effect on the clearance of autophagy substrate P62 and α-synuclein, the core pathological products of Parkinson’s disease (PD), to provide…
-
Artikel Jurnal Teks lengkap
Universal Stem-Loop Primer Method for Screening and Quantification of MicroRNA
RT-qPCR is the accepted technique for the quantification of microRNA (miR) expression: however, stem-loop RT-PCR, the most frequently used method for quantification of miRs, is time- and reagent-consuming as well as inconvenient for scanning. We established a new method called ‘universal stem-loop…
-
Artikel Jurnal Teks lengkap
Association between Ankylosing Spondylitis and the miR-146a and miR-499 Polymorphisms
miRNAs are small, non-coding RNAs that regulate the expression of multiple target genes at the post-transcriptional level. Single-nucleotide polymorphisms (SNPs) in miRNA sequences may alter miRNA expression and have been implicated in the pathogenesis of multiple forms of arthritis, including…
-
Artikel Jurnal Teks lengkap
Association of Single-Nucleotide Polymorphisms in Monoubiquitinated FANCD2-DNA Damage Repair Pathway Genes With Breast Cancer in the Chinese Population
OBJECTIVE: The aim of the study was to estimate breast cancer risk conferred by individual single-nucleotide polymorphisms of breast cancer susceptibility genes. METHODS: We analyzed the 48 tagging single-nucleotide polymorphisms of 8 breast cancer susceptibility genes involved in the…