5 hasil untuk "Thilo Hackert"
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Artikel Jurnal Teks lengkap
Development of a hypoxia-responsive macrophage prognostic model using single-cell and bulk RNA sequencing in pancreatic cancer
Objective: Pancreatic ductal adenocarcinoma (PDAC) is characterized by a low survival rate and limited responsiveness to current therapies. The role of hypoxia in the tumor microenvironment is critical, influencing tumor progression and therapy resistance. The aim of this study was to implement the…
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Artikel Jurnal Teks lengkap
Epithelial to Stromal Re-Distribution of Primary Cilia during Pancreatic Carcinogenesis
Background: The Hedgehog (HH) pathway is a mediator in pancreatic ductal adenocarcinoma (PDAC). Surprisingly, previous studies suggested that primary cilia (PC), the essential organelles for HH signal transduction, were lost in PDAC. The aim of this study was to determine the presence of PC in…
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Artikel Jurnal Teks lengkap
Impact of progressive resistance training on CT quantified muscle and adipose tissue compartments in pancreatic cancer patients
Objectives: Loss of body weight is often seen in pancreatic cancer and also predicts poor prognosis. Thus, maintaining muscle mass is an essential treatment goal. The primary aim was to investigate whether progressive resistance training impacts muscle and adipose tissue compartments. Furthermore…
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Artikel Jurnal Teks lengkap
2-octyl cyanoacrylate sealing of the pancreatic remnant after distal pancreatectomy – A prospective pilot study
Background: Postoperative pancreatic fistula (POPF) remains a frequent problem especially after distal pancreatectomy. The application of 2-octyl cyanoacrylate showed promising results in the reduction of POPF after pancreatoduodenectomy prompting an expansion of this technique to distal…
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Artikel Jurnal Teks lengkap
Bicarbonate buffered peritoneal dialysis fluid upregulates angiopoietin-1 and promotes vessel maturation
Background: Ultrafiltration decline is a progressive issue for patients on chronic peritoneal dialysis (PD) and can be caused by peritoneal angiogenesis induced by PD fluids. A recent pediatric trial suggests better preservation of ultrafiltration with bicarbonate versus lactate buffered fluid…