1 hasil untuk "Tracy Cheever"

Improved delivery of broadly neutralizing antibodies by nanocapsules suppresses SHIV infection in the CNS of infant rhesus macaques

Jing Wen; Tracy Cheever; Lan Wang dkk.

PLOS Pathogens, Vol. 17 No. 7 · 2021 · Inggris · PLOS Scopus

Broadly neutralizing antibodies (bNAbs) directed to HIV-1 have shown promise at suppressing viremia in animal models. However, the use of bNAbs for the central nervous system (CNS) infection is confounded by poor penetration of the blood brain barrier (BBB). Typically, antibody concentrations in…