21 hasil untuk "Vogel, K"

Variation of iStent Procedure Rates by State in Response to the COVID-19 Pandemic

Vogel K; Rojas CN; Tanna AP dkk.

Clinical Ophthalmology, Vol. Volume 16 · 2022 · Inggris · DOAJ Scopus

Kelly Vogel,1 Cole N Rojas,1 Angelo P Tanna,1 Dustin D French1– 4 1Department of Ophthalmology, Northwestern University Feinberg School of Medicine, Chicago, IL, USA; 2Department of Medical Social Science, Northwestern University Feinberg School of Medicine, Chicago, Illinois, USA; 3Center for…

The two positively acting regulatory proteins PHO2 and PHO4 physically interact with PHO5 upstream activation regions.

Vogel, K; Hörz, W; Hinnen, A

Mol Cell Biol · 1989 · Inggris · PubMed Central

The repressible acid phosphatase gene PHO5 of Saccharomyces cerevisiae requires the two positively acting regulatory proteins PHO2 and PHO4 for expression. pho2 or pho4 mutants are not able to derepress the PHO5 gene under low-Pi conditions. Here we show that both PHO2 and PHO4 bind specifically to…

A yeast tRNA precursor containing a pre-mRNA intron is spliced via the pre-mRNA splicing mechanism.

Köhrer, K; Vogel, K; Domdey, H

EMBO J · 1990 · Inggris · PubMed Central

We have replaced the 14 nucleotide long intervening sequence of the Saccharomyces cerevisiae SUP6 (ochre) tRNA(Tyr) gene by the 52 nucleotide long second intron of the S. cerevisiae MATa1 gene. Yeast cells containing this modified pre-tRNA showed the typical suppressor phenotype indicating that the…

Production of proteoglycans by human lung fibroblasts (IMR-90) maintained in a low concentration of serum.

Vogel, K G; Sapién, R E

Biochem J · 1982 · Inggris · PubMed Central

Maintenance of fibroblasts in 0.5% serum results in viable but non-proliferative cells that may be analogous to fibroblasts in vivo. The synthesis of proteoglycans by human embryo lung fibroblasts in Eagle's minimal essential medium with 0.5% newborn-bovine serum or with 10% serum has been…

Proteoglycan synthesis in organ cultures from regions of bovine tendon subjected to different mechanical forces.

Koob, T J; Vogel, K G

Biochem J · 1987 · Inggris · PubMed Central

Synthesis of proteoglycans by morphologically and chemically distinct regions of bovine flexor tendon was investigated in explant cultures. Proximal regions of the flexor tendon which experience only tensile forces and have low contents of proteoglycans initially exhibited relatively low rates of…

Specific inhibition of type I and type II collagen fibrillogenesis by the small proteoglycan of tendon.

Vogel, K G; Paulsson, M; Heinegård, D

Biochem J · 1984 · Inggris · PubMed Central

The small dermatan sulphate proteoglycan of bovine tendon demonstrated a unique ability to inhibit fibrillogenesis of both type I and type II collagen from bovine tendon and cartilage respectively in an assay performed in vitro. None of the other proteoglycan populations from cartilage, tendon or…

Identification of pre-mRNA polyadenylation sites in Saccharomyces cerevisiae.

Heidmann, S; Obermaier, B; Vogel, K dkk.

Mol Cell Biol · 1992 · Inggris · PubMed Central

In contrast to higher eukaryotes, little is known about the nature of the sequences which direct 3'-end formation of pre-mRNAs in the yeast Saccharomyces cerevisiae. The hexanucleotide AAUAAA, which is highly conserved and crucial in mammals, does not seem to have any functional importance for…

Impact of the COVID-19 Pandemic on Cataract Surgeries in the United States

Vogel K; Rojas CN; Greenberg PB dkk.

Clinical Ophthalmology, Vol. Volume 16 · 2022 · Inggris · DOAJ Scopus

Kelly Vogel,1 Cole N Rojas,1 Paul B Greenberg,2,3 Curtis E Margo,4 Dustin D French1,5– 7 1Department of Ophthalmology, Feinberg School of Medicine, Northwestern University, Chicago, IL, USA; 2Division of Ophthalmology, Alpert Medical School, Brown University, Providence, RI, USA; 3Section of…

Interpathway regulation of the TRP4 gene of yeast.

Braus, G; Mösch, H U; Vogel, K dkk.

EMBO J · 1989 · Inggris · PubMed Central

Two regulatory proteins, PHO2 and the general control regulator GCN4, bind in vitro to the promoter of the tryptophan biosynthetic TRP4 gene; the TRP4 gene product catalyses the phosphoribosylation of anthranilate. PHO2 binds specifically to the TRP4 promoter, but does not bind to any other TRP…

Myelodysplasia in Two Pig-Tailed Macaques (Macaca nemestrina) Associated with Retroviral Vector Mediated Insertional Mutagenesis and Overexpression of HOXB4

Murnane, R.; Zhang, X.B.; Hukkanen, R.R. dkk.

Vet Pathol · 2010 · Inggris · PubMed Central

Gammaretroviral vectors are an efficient means to effect gene therapy. However, genotoxicity from insertion at non-random sites can confer a competitive advantage to transduced cells resulting in clonal proliferation or neoplasia. Six pig-tailed macaques (Macaca nemestrina) underwent total body…

Net energy of cellulosic ethanol from switchgrass

Schmer, M. R.; Vogel, K. P.; Mitchell, R. B. dkk.

Proc Natl Acad Sci U S A · 2008 · Inggris · PubMed Central

Perennial herbaceous plants such as switchgrass (Panicum virgatum L.) are being evaluated as cellulosic bioenergy crops. Two major concerns have been the net energy efficiency and economic feasibility of switchgrass and similar crops. All previous energy analyses have been based on data from…

Targeted mutation in the neurotrophin-3 gene results in loss of muscle sensory neurons.

Tessarollo, L; Vogel, K S; Palko, M E dkk.

Proc Natl Acad Sci U S A · 1994 · Inggris · PubMed Central

Neurotrophin 3 (NT-3) is one of four related polypeptide growth factors that share structural and functional homology to nerve growth factor (NGF). NT-3 and its receptor, called neurotrophic tyrosine kinase receptor type 3 (Ntrk3; also called TrkC), are expressed early and throughout embryogenesis…

Extending certified spectral fluorescence standards for the calibration and performance validation of fluorescence instruments to the NIR—closing the gap from 750 to 940 nm with two novel NIR dyes

Richter, M.; Güttler, A.; Pauli, J. dkk.

Anal Bioanal Chem · 2025 · Inggris · PubMed Central

Fluorescence techniques such as fluorescence spectroscopy, microfluorometry, and fluorescence microscopy, providing spectral, intensity, polarization, and lifetime information, are amongst the most broadly utilized analytical methods in the life and materials sciences. However, the measured…

Analysis of exhausted T cells, systemically enhanced cytokine levels ex vivo and Machine Learning Facilitated Search for Ageing-Related Biomarkers

Beyer, C; Jamaludeen, N; Vogel, K dkk.

Gesundheitswesen · 2022 · Jerman · PubMed Central

Sequence and transcriptional start site of the Pseudomonas aeruginosa outer membrane porin protein F gene.

Duchêne, M; Schweizer, A; Lottspeich, F dkk.

J Bacteriol · 1988 · Inggris · PubMed Central

Porin F is one of the major proteins of the outer membrane of Pseudomonas aeruginosa. It forms water-filled pores of variable size. Porin F is a candidate for a vaccine against P. aeruginosa because it antigenically cross-reacts in all serotype strains of the International Antigenic Typing Scheme…

Characterization of an ester-based core-multishell (CMS) nanocarrier for the topical application at the oral mucosa

Dommisch, H.; Stolte, KN.; Jager, J. dkk.

Clin Oral Investig · 2021 · Inggris · PubMed Central

OBJECTIVES: Topical drug administration is commonly applied to control oral inflammation. However, it requires sufficient drug adherence and a high degree of bioavailability. Here, we tested the hypothesis whether an ester-based core-multishell (CMS) nanocarrier is a suitable nontoxic drug-delivery…

Dynamics of laser-induced lattice formation in Bose-Einstein condensates

Kalinski, M.; Mazets, I. E.; Kurizki, G. dkk.

arXiv · 2003 · Inggris · arXiv

We present variational and numerical solutions of the generalized Gross--Pitaevskii equation for an atomic Bose--Einstein condensate with time-dependent, laser-induced dipole-dipole interactions (LIDDI). The formation of a supersolid ground state due to LIDDI in an elongated (cigar-shaped) BEC is…

Quantum tunneling of semifluxons

Goldobin, E.; Vogel, K.; Crasser, O. dkk.

arXiv · 2005 · Inggris · arXiv

We consider a system of two semifluxons of opposite polarity in a 0-pi-0 long Josephson junction, which classically can be in one of two degenerate states: up-down or down-up. When the distance $a$ between the 0-pi boundaries (semifluxon's centers) is a bit larger than the crossover distance $a_c$…

The core proteins of large and small interstitial proteoglycans from various connective tissues form distinct subgroups.

Heinegård, D; Björne-Persson, A; Cöster, L dkk.

Biochem J · 1985 · Inggris · PubMed Central

Large and small proteoglycans were separately isolated from a number of connective tissues and compared to determine the extent of structural similarity. This was studied by enzyme-linked immunosorbent assays and by the peptide patterns obtained when 125I-labelled proteoglycans were digested with…

De novo heme proteins from designed combinatorial libraries.

Rojas, N. R.; Kamtekar, S.; Simons, C. T. dkk.

Protein Sci · 1997 · Inggris · PubMed Central

We previously reported the design of a library of de novo amino acid sequences targeted to fold into four-helix bundles. The design of these sequences was based on a "binary code" strategy, in which the patterning of polar and nonpolar amino acids is specified explicitly, but the exact identities…