35 hasil untuk "Wu, Li-Hong"
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The complete chloroplast genome of Hemerocallis citrina (Asphodelaceae), an ornamental and medicinal plant
Hemerocallis citrina (Asphodelaceae) has been wildly cultivated as ornamental and medicinal plant. Here, we reported the first chloroplast genome sequence of H. citrina. The chloroplast genome size is 156,088 bp with GC content of 37.3%, including a large single-copy (LSC) of 84,843 bp, a small…
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Mitochondrial genome and phylogenetic analysis of Psylliodes punctifrons Baly (Coleoptera: Chrysomelidae: Galerucinae)
We sequenced and annotated mitochondrial genome (mitogenome) of oilseed rape pest Psylliodes punctifrons Baly for the first time. The mitogenome is 15,611 bp, and the nucleotide composition of 37 genes is highly A + T biased (A: 34.2, C: 11.6, G: 12.1, and T:42.1). All PCGs start with ATN and stop…
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Metagenomic profiling of gut microbiota in Fall Armyworm (Spodoptera frugiperda) larvae fed on different host plants
BACKGROUND: The fall armyworm (FAW, Spodoptera frugiperda) is a polyphagous pest known for causing significant crop damage. The gut microbiota plays a pivotal role in influencing the biology, physiology and adaptation of the host. However, understanding of the taxonomic composition and functional…
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Frontal lobe development in fetuses with growth restriction by using ultrasound: a case–control study
BACKGROUND: Fetal growth restriction (FGR) occurs in up to 10% of pregnancies and is a leading cause of perinatal mortality and neonatal morbidity. Three-dimensional ultrasonography of intracranial structure volume revealed significant differences between fetuses with FGR and appropriate for…
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Abnormally cleaving embryos are able to produce live births: a time-lapse study
PURPOSE: This study investigated the prevalence of abnormally cleaved embryos and determined which types of abnormally cleaved embryos (1-3c, 2-4c, 3-5c, 4-6c), might be suitable for transfer based on live birth data. METHODS: One hundred seventy-one women (whose transferred embryos were confirmed…
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Dimensions of the optic chiasm: quantitative ultrasound comparison between fetuses with anophthalmia/microphthalmia and normal fetuses
BACKGROUND: The precise pathogenesis of anophthalmia/microphthalmia remains unknown. Prenatal observation of the optic chiasm in fetuses with this malformation would assist in understanding the embryonic development of the condition. The present study aimed to establish the normal fetal size ranges…
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Changes in the esophagogastric junction outflow obstruction manometric feature based on the Chicago Classification updates
BACKGROUND: The critical diagnostic criteria for esophagogastric junction outflow obstruction (EGJOO) were published in the latest Chicago Classification version 4.0 (CCv4.0). In addition to the previous criterion [elevated integrated relaxation pressure (IRP) in supine position], manometric…
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Stratifying hepatocellular carcinoma based on immunophenotypes for immunotherapy response and prognosis
Immunotherapy has transformed the management of hepatocellular carcinoma (HCC), but effectiveness varies among patients. This study aimed to identify biomarkers and HCC subtypes responsive to immunotherapy. Patients were classified into Immunity-High (Immunity-H) and Immunity-Low (Immunity-L)…
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Construction and validation of a prognosis signature based on the immune microenvironment in gastric cancer
BACKGROUND: Gastric cancer (GC) is an aggressive malignant tumor with a high degree of heterogeneity, and its immune microenvironment is closely associated with tumor growth, development and drug resistance. Therefore, a classification system of gastric cancer based explicitly on the immune…
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Construction of an HCC recurrence model basedon the investigation of immune-relatedlncRNAs and related mechanisms
Long noncoding RNAs (lncRNAs) are emerging as critical regulators of gene expression and play fundamental roles in immune regulation. Growing evidence suggests that immune-related genes and lncRNAs can serve as markers to predict the prognosis of patients with cancers, including hepatocellular…
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Calcitonin gene‑related peptide alleviates hyperoxia‑induced human alveolar cell injury via the CGRPR/TRPV1/Ca2(+) axis
Although exogenous calcitonin gene-related peptide (CGRP) protects against hyperoxia-induced lung injury (HILI), the underlying mechanisms remain unclear. The present study attempted to elucidate the molecular mechanism by which CGRP protects against hyperoxia-induced alveolar cell injury. Human…
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A Novel Aldisine Derivative Exhibits Potential Antitumor Effects by Targeting JAK/STAT3 Signaling
The JAK/STAT3 signaling pathway is aberrantly hyperactivated in many cancers, promoting cell proliferation, survival, invasiveness, and metastasis. Thus, inhibitors targeting JAK/STAT3 have enormous potential for cancer treatment. Herein, we modified aldisine derivatives by introducing the…
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Characterization of lactylation modification subtypes and the promoting role of CCL20 in hepatocellular carcinoma progression
BACKGROUND: Hepatocellular carcinoma (HCC) is a highly aggressive and deadly malignancy. Early identification of prognostic risk factors is crucial for guiding clinical management and improving patient outcomes. Lactylation modification plays a pivotal role in tumorigenesis, yet the regulatory…
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A Retrospective Study for Labia Minora Reduction by Serrated-shaped Resection
BACKGROUND: The demand for genital plastic surgery has increased dramatically among female patients globally. Although various labia minora reduction procedures have been applied with different indications, advantages, and disadvantages, none has been universally accepted as the best method. So, we…
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In vitro activity of chlorogenic acid against Aspergillus fumigatus biofilm and gliotoxin production
Aspergillus (A.) fumigatus, one of the most common causes of life-threatening fungal infections in immunocompromised patients, shows resistance to antifungal agents as has a high propensity to forming a biofilm. The present study aimed to investigate the effects of chlorogenic acid (CRA) on A…
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Effect of Prepregnancy Obesity on Litter Size in Primiparous Minipigs
Obesity is a public health problem in both developed and developing countries, and the negative effects of obesity on reproductive physiology have been highlighted recently. We evaluated the effects of porcine obesity index, sex hormones, and peptide hormones on litter size in various breeds of…
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Withania somnifera Root Extract Enhances Chemotherapy through ‘Priming’
Withania somnifera extracts are known for their anti-cancerous, anti-inflammatory and antioxidative properties. One of their mechanisms of actions is to modulate mitochondrial function through increasing oxidative stress. Recently ‘priming’ has been suggested as a potential mechanism for enhancing…
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Effect of ART treatments on maternal and neonatal outcomes in singleton live births: A large-scale retrospective cohort study
BACKGROUND: The increased risk of pregnancy complications in the ART population has been reported, but the source of these risks remains controversial. The study aims to evaluate the association between ART treatments and patient characteristics with maternal and neonatal outcomes. METHODS: This…
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Endothelin 3/EDNRB signaling induces thermogenic differentiation of white adipose tissue
Thermogenic adipose tissue, consisting of brown and beige fat, regulates nutrient utilization and energy metabolism. Human brown fat is relatively scarce and decreases with obesity and aging. Hence, inducing thermogenic differentiation of white fat offers an attractive way to enhance whole-body…
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Identifying specific TLS-associated genes as potential biomarkers for predicting prognosis and evaluating the efficacy of immunotherapy in soft tissue sarcoma
BACKGROUND: The tertiary lymphatic structure (TLS) is an important component of the tumor immune microenvironment and has important significance in patient prognosis and response to immune therapy. However, the underlying mechanism of TLS in soft tissue sarcoma remains unclear. METHODS: A total of…