26 hasil untuk "YANG Zichen"
Menampilkan 1–20 · 0,52 detik · RSS
-
Artikel Jurnal
Artemisia annua L. in treatment for Mycobacterium abscessus infection based on network pharmacology, molecular docking and in vitro experiments
Objective To explore the mechanism of Artemisia annua L. (A. annua) in treatment of Mycobacterium abscessus (M. abscessus) infection with aid of network pharmacology and molecular docking. Methods The active components of A. annua were obtained from the Traditional Chinese Medicine System…
-
Artikel Jurnal Teks lengkap
Research on the method of shiitake mushroom picking robot based on CSO-ASTGCN human action prediction network
INTRODUCTION: Automating shiitake mushroom picking is critical for modern agriculture, yet its biological traits hinder automation via target recognition, path planning, and precision challenges. Traditional manual picking is inefficient, labor-heavy, and unsuitable for large-scale production. In…
-
Artikel Jurnal Teks lengkap
Lytic Bacteriophage Screening Strategies for Multidrug-Resistant Bloodstream Infections in a Burn Intensive Care Unit
BACKGROUND: Increasing antibiotic resistance and multidrug resistance (MDR) in patients with bloodstream infection (BSI) has resulted in treatment using bacteriophage. This study aimed to identify Gram-negative bacilli and Gram-positive cocci and antibiotic resistance in patients with BSI in a burn…
-
Artikel Jurnal Teks lengkap
Epidemiology and molecular typing of multidrug resistant Acinetobacter baumannii burn wound isolates from six Chinese provinces
Acinetobacter baumannii (A. baumannii) is a pathogen that opportunistically infects patients in healthcare settings and poses a significant threat to human health due to its widespread resistance to antimicrobial agents. The temporal and regional distribution of A. baumannii in China is continually…
-
Artikel Jurnal Teks lengkap
A Carboxymethyl Chitosan Hydrogel Loaded with Bacteriophage-Derived Bacteriostatic Peptide Exhibits Antibacterial, Hemostatic, and Wound-Healing Properties
Drug-resistant bacterial infections are a formidable challenge in the treatment of skin and soft tissue wounds due to the limited efficacy of currently available antibiotics. Bacteriophage-derived antimicrobial peptides positioned as promising antibacterial agents offer a new solution to this…
-
Artikel Jurnal Teks lengkap
Combined inflammatory-lipid index and tumor markers for predicting the spatial localization of lesions in early-stage non-small cell lung cancer
OBJECTIVE: This study evaluated the predictive value of combined inflammatory-lipid indices and tumor markers in determining lesion localization in early-stage non-small cell lung cancer (NSCLC) and developed a predictive model. METHODS: A retrospective analysis of 206 early-stage NSCLC patients…
-
Artikel Jurnal Teks lengkap
Molecular mechanism mediating enteric bacterial translocation after severe burn: the role of cystic fibrosis transmembrane conductance regulator
BACKGROUND: Gut ischemia and hypoxia post severe burn leads to breakdown of intestinal epithelial barrier and enteric bacterial translocation (EBT), resulting in serious complications, such as systemic inflammatory response syndrome, sepsis and multiple organ failure. Cystic fibrosis transmembrane…
-
Artikel Jurnal Teks lengkap
Application of bacteriophage φPaP11-13 attenuates rat Cutibacterium acnes infection lesions by promoting keratinocytes apoptosis via inhibiting PI3K/Akt pathway
Acne vulgaris caused by antibiotic-resistant Cutibacterium acnes (C. acnes) infection is difficult to treat conventionally. Phages have been suggested as a potential solution, but research on the mechanism of phage treatment is inadequate. This research investigates the underlying molecular…
-
Artikel Jurnal Teks lengkap
Construction of a QSAR Model Based on Flavonoids and Screening of Natural Pancreatic Lipase Inhibitors
Pancreatic lipase (PL) is a key hydrolase in lipid metabolism. Inhibition of PL activity can intervene in obesity, a global sub-health disease. The natural product is considered a good alternative to chemically synthesized drugs due to its advantages, such as low side effects. However, traditional…
-
Artikel Jurnal Teks lengkap
Accumulation of Fascin(+) cells during experimental autoimmune neuritis
BACKGROUND: Experimental autoimmune neuritis (EAN) is a well-known animal model of human demyelinating polyneuropathies and is characterized by inflammation and demyelination in the peripheral nervous system. Fascin is an evolutionarily highly conserved cytoskeletal protein of 55 kDa containing two…
-
Artikel Jurnal Teks lengkap
Whole-genome sequencing, annotation, and biological characterization of a novel Siphoviridae phage against multi-drug resistant Propionibacterium acne
Antibiotics-resistant Propionibacterium acne (P. acne) causes severe acne vulgaris, serious public health, and psychological threat. A new lytic bacteriophage (phage), φPaP11-13, infecting P. acne, was isolated from the sewage management center of Xinqiao Hospital. It can form transparent plaque…
-
Artikel Jurnal Teks lengkap
Construction of an MLR-QSAR Model Based on Dietary Flavonoids and Screening of Natural α-Glucosidase Inhibitors
Postprandial hyperglycemia can be reduced by inhibiting α-glucosidase activity. Common α-glucosidase inhibitors such as acarbose may have various side effects. Therefore, it is important to find natural products that are non-toxic and have high α-glucosidase-inhibitory activity. In the present…
-
Artikel Jurnal Teks lengkap
Burn Injury Leads to Increase in Relative Abundance of Opportunistic Pathogens in the Rat Gastrointestinal Microbiome
The gastrointestinal microbiome is crucial in human health. With greater than 10 times the cell count of an individual, the gastrointestinal microbiome provides many benefits to the host. It plays an important role in chronic illnesses and immune diseases and also following burns and trauma. This…
-
Artikel Jurnal Teks lengkap
Late-Onset Acute Kidney Injury is a Poor Prognostic Sign for Severe Burn Patients
BACKGROUND: Acute kidney injury (AKI) is a morbid complication and the main cause of multiple organ failure and death in severely burned patients. The objective of this study was to explore epidemiology, risk factors, and outcomes of AKI for severely burned patients. METHODS: This retrospective…
-
Artikel Jurnal Teks lengkap
Comparative genomics and DNA methylation analysis of Pseudomonas aeruginosa clinical isolate PA3 by single-molecule real-time sequencing reveals new targets for antimicrobials
INTRODUCTION: Pseudomonas aeruginosa (P.aeruginosa) is an important opportunistic pathogen with broad environmental adaptability and complex drug resistance. Single-molecule real-time (SMRT) sequencing technique has longer read-length sequences, more accuracy, and the ability to identify epigenetic…
-
Artikel Jurnal Teks lengkap
Global Transcriptomic Analysis of the Interactions between Phage φAbp1 and Extensively Drug-Resistant Acinetobacter baumannii
Acinetobacter baumannii is a growing threat, although lytic bacteriophages have been shown to effectively kill A. baumannii. However, the interaction between the host and the phage has not been fully studied. We demonstrate the global profile of transcriptional changes in extensively drug-resistant…
-
Artikel Jurnal Teks lengkap
Paramagnons and high-temperature superconductivity in a model family of cuprates
Cuprate superconductors have the highest critical temperatures (T(c)) at ambient pressure, yet a consensus on the superconducting mechanism remains to be established. Finding an empirical parameter that limits the highest reachable T(c) can provide crucial insight into this outstanding problem…
-
Artikel Jurnal Teks lengkap
Author Correction: Paramagnons and high-temperature superconductivity in a model family of cuprates
-
Artikel Jurnal
Effect of exposure to typical phthalate esters on estrogen homeostasis during pregnancy
ObjectiveTo study the relationship between the exposure to two kinds of phthalate esters （PAEs） ［Di-N-butyl phthalate，（DBP） and Di-（2-ethylhexyl）phthalate （DEHP）］ and estrogen homeostasis in pregnant women.MethodsIn 2021， we classified the Jiading District of Shanghai into five geographical areas，…