64 hasil untuk "Yan Lin"

Stress Tolerance Variations in Saccharomyces cerevisiae Strains from Diverse Ecological Sources and Geographical Locations

Yan-Lin Zheng; Shi-An Wang

PLOS ONE, Vol. 10 No. 8 · 2015 · Inggris · PLOS Scopus

The budding yeast Saccharomyces cerevisiae is a platform organism for bioethanol production from various feedstocks and robust strains are desirable for efficient fermentation because yeast cells inevitably encounter stressors during the process. Recently, diverse S. cerevisiae lineages were…

Transformational leadership and teacher resilience in Chinese Universities: The chain mediating role of perceived organisational support and work engagement

Ziliang Li; Liqin Liu; Yan Lin

PLOS One, Vol. 21 No. 5 · 2026 · Inggris · PLOS Scopus

In the context of global changes in higher education, the development mechanism of teachers’ professional resilience, as a key psychological capital for maintaining education quality and institutional core competitiveness, needs to be systematically examined. Based on the organisational context of…

Association of rs6265 and rs2030324 Polymorphisms in Brain-Derived Neurotrophic Factor Gene with Alzheimer’s Disease: A Meta-Analysis

Yan Lin; Shuo Cheng; Zhutian Xie dkk.

PLoS ONE, Vol. 9 No. 4 · 2014 · Inggris · PLOS Scopus

Background: The association between polymorphisms rs6265 and rs2030324 in brain-derived neurotrophic factor (BDNF) and Alzheimer’s disease (AD) has been widely reported, but the results remain controversial. Methods: A comprehensive search of Pubmed, Web of Science, China National Knowledge…

AGEs Decrease Insulin Synthesis in Pancreatic β-Cell by Repressing Pdx-1 Protein Expression at the Post-Translational Level

Tingting Shu; Yunxia Zhu; Hongdong Wang dkk.

PLoS ONE, Vol. 6 No. 4 · 2011 · Inggris · PLOS Scopus

Advanced glycation end products (AGEs) have been implicated in diverse pathological settings of many diabetic complications, and the possible mechanisms have been widely reported. However, the relationship between AGEs and pancreatic β-cell dysfunction is still poorly understood. Recent studies…

Construction of Taiwanese Adult Reference Phantoms for Internal Dose Evaluation

Shu-Jun Chang; Shih-Yen Hung; Yan-Lin Liu dkk.

PLOS ONE, Vol. 11 No. 9 · 2016 · Inggris · PLOS Scopus

In the internal dose evaluation, the specific absorbed fraction (SAF) and S-value are calculated from the reference phantom based on Caucasian data. The differences in height and weight between Caucasian and Asian may lead to inaccurate dose estimation. In this study, we developed the Taiwanese…

Sleepless in America: A social sensing study of pandemic-era sleeplessness using nighttime social media data

Xi Gong; Lin Liu; Yujian Lu dkk.

PLOS One, Vol. 21 No. 9 · 2026 · Inggris · PLOS Scopus

Sleeplessness is a widespread public health concern that was further intensified during the COVID-19 pandemic, yet large-scale, real-time monitoring of sleep disturbance remains limited. This study introduces a scalable social sensing framework that leverages temporally filtered nighttime social…

Sigma-1 Receptor Agonists Directly Inhibit Na V 1.2/1.4 Channels

Xiao-Fei Gao; Jin-Jing Yao; Yan-Lin He dkk.

PLoS ONE, Vol. 7 No. 11 · 2012 · Inggris · PLOS Scopus

(+)-SKF 10047 (N-allyl-normetazocine) is a prototypic and specific sigma-1 receptor agonist that has been used extensively to study the function of sigma-1 receptors. (+)-SKF 10047 inhibits K+, Na+ and Ca2+ channels via sigma-1 receptor activation. We found that (+)-SKF 10047 inhibited NaV1.2 and…

Reproductive Hormone and Transcriptomic Responses of Pituitary Tissue in Anestrus Gilts Induced by Nutrient Restriction

Shengyu Xu; Dingyue Wang; Dongsheng Zhou dkk.

PLOS ONE, Vol. 10 No. 11 · 2015 · Inggris · PLOS Scopus

The onset of estrus is a critical sign of female sexual maturity. The pituitary plays a vital role in this process by the secretion of reproductive hormones. To investigate the effects of nutrient restriction on reproductive function and the underlying mechanisms involved, deep RNA sequencing of…

Diagnostic Performance of Indocyanine Green-Guided Sentinel Lymph Node Biopsy in Breast Cancer: A Meta-Analysis

Xiaohui Zhang; Yan Li; Yidong Zhou dkk.

PLOS ONE, Vol. 11 No. 6 · 2016 · Inggris · PLOS Scopus

Background: The diagnostic performance of indocyanine green (ICG) fluorescence-guided sentinel lymph node biopsy (SLNB) for the presence of metastases in breast cancer remains unclear. Objective: We performed a meta-analysis to investigate the diagnostic performance of ICG-guided SLNB. Methods…

An improved X-means and isolation forest based methodology for network traffic anomaly detection

Yifan Feng; Weihong Cai; Haoyu Yue dkk.

PLOS ONE, Vol. 17 No. 1 · 2022 · Inggris · PLOS Scopus

Anomaly detection in network traffic is becoming a challenging task due to the complexity of large-scale networks and the proliferation of various social network applications. In the actual industrial environment, only recently obtained unlabelled data can be used as the training set. The accuracy…

Corticosteroid-Binding Globulin: Structure-Function Implications from Species Differences

Bernd R. Gardill; Michael R. Vogl; Hai-Yan Lin dkk.

PLoS ONE, Vol. 7 No. 12 · 2012 · Inggris · PLOS Scopus

Corticosteroid-binding globulin (CBG) transports glucocorticoids and progesterone in the blood and thereby modulates the tissue availability of these hormones. As a member of the serine protease inhibitor (SERPIN) family, CBG displays a reactive center loop (RCL) that is targeted by proteinases…

Liver X Receptor Gene Polymorphisms in Tuberculosis: Effect on Susceptibility

Min Han; Li Liang; Li-rong Liu dkk.

PLoS ONE, Vol. 9 No. 5 · 2014 · Inggris · PLOS Scopus

Objectives: The Liver X receptors (LXRs), Liver X receptor A (LXRA) and Liver X receptor B (LXRB), regulate lipid metabolism and antimicrobial response. LXRs have a crucial role in the control of Mycobacterium tuberculosis (M.tb). Lacking LXRs mice is more susceptibility to infection M.tb…

Patients with Knee Osteoarthritis Undergoing Total Knee Arthroplasty Have a Lower Risk of Subsequent Severe Cardiovascular Events: Propensity Score and Instrumental Variable Analysis

Wen-Yan Lin; Ching-Chih Lee; Chia-Wen Hsu dkk.

PLOS ONE, Vol. 10 No. 5 · 2015 · Inggris · PLOS Scopus

Objective: This population-based study investigated the subsequent cardiovascular risk of patients with knee osteoarthritis underwent total knee arthroplasty in Taiwan. Materials and methods: This was a population-based follow-up study of 22931 patients diagnosed with knee osteoarthritis between…

Inter-Species Grafting Caused Extensive and Heritable Alterations of DNA Methylation in Solanaceae Plants

Rui Wu; Xiaoran Wang; Yan Lin dkk.

PLoS ONE, Vol. 8 No. 4 · 2013 · Inggris · PLOS Scopus

Background: Grafting has been extensively used to enhance the performance of horticultural crops. Since Charles Darwin coined the term “graft hybrid” meaning that asexual combination of different plant species may generate products that are genetically distinct, highly discrepant opinions exist…

High efficiency cabin air filter in vehicles reduces drivers' roadway particulate matter exposures and associated lipid peroxidation

Nu Yu; Shi Shu; Yan Lin dkk.

PLOS ONE, Vol. 12 No. 11 · 2017 · Inggris · PLOS Scopus

Commuters who spend long hours on roads are exposed to high levels of traffic related air pollutants (TRAPs). Despite some well-known multiple adverse effects of TRAPs on human health, limited studies have focused on mitigation strategies to reduce these effects. In this study, we measured fine…

Diversity and Antimicrobial Activity of Culturable Endophytic Fungi Isolated from Moso Bamboo Seeds

Xiao-Ye Shen; Yan-Lin Cheng; Chun-Ju Cai dkk.

PLoS ONE, Vol. 9 No. 4 · 2014 · Inggris · PLOS Scopus

Bamboos, regarded as therapeutic agents in ethnomedicine, have been used to inhibit inflammation and enhance natural immunity for a long time in Asia, and there are many bamboo associated fungi with medical and edible value. In the present study, a total of 350 fungal strains were isolated from the…

Surveillance of hepatocellular carcinoma (HCC) patients using Protein Induced by Vitamin K (PIVKA-II): A cost-utility analysis for Hong Kong

Man-Fung Yuen; David Wastlund; Tammie Tan Yan Lin dkk.

PLOS One, Vol. 21 No. 7 · 2026 · Inggris · PLOS Scopus

Background & Aims: Hepatocellular carcinoma (HCC) is a leading cause of cancer-related death in Hong Kong. Common risk factors include chronic hepatitis B (CHB) infection and/ or liver cirrhosis (LC). Routine HCC surveillance using ultrasound plus alpha-fetoprotein (AFP) for patients with these…

Correction: Momordica charantia (Bitter Melon) Reduces Obesity-Associated Macrophage and Mast Cell Infiltration as well as Inflammatory Cytokine Expression in Adipose Tissues

Bin Bao; Yan-Guang Chen; Lei Zhang dkk.

PLoS ONE, Vol. 9 No. 1 · 2014 · Inggris · PLOS Scopus

Momordica charantia (Bitter Melon) Reduces Obesity-Associated Macrophage and Mast Cell Infiltration as well as Inflammatory Cytokine Expression in Adipose Tissues

Bin Bao; Yan-Guang Chen; Lei Zhang dkk.

PLoS ONE, Vol. 8 No. 12 · 2013 · Inggris · PLOS Scopus

Obesity is a world-wide epidemic disease that correlates closely with type 2 diabetes and cardiovascular diseases. Obesity-induced chronic adipose tissue inflammation is now considered as a critical contributor to the above complications. Momordica charantia (bitter melon, BM) is a traditional…

Cyproheptadine Enhances the I K of Mouse Cortical Neurons through Sigma-1 Receptor-Mediated Intracellular Signal Pathway

Yan-Lin He; Chun-Lei Zhang; Xiao-Fei Gao dkk.

PLoS ONE, Vol. 7 No. 7 · 2012 · Inggris · PLOS Scopus

Cyproheptadine (CPH) is a histamine- and serotonin-receptor antagonist, and its effects are observed recently in the modulation of multiple intracellular signals. In this study, we used cortical neurons and HEK-293 cells transfected with Kv2.1 α-subunit to address whether CPH modify neural…