2 results for "Yuling Peng"
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Journal Article Full text
Partial inhibition of class III PI3K VPS-34 ameliorates motor aging and prolongs health span
Global increase of life expectancy is rarely accompanied by increased health span, calling for a greater understanding of age-associated behavioral decline. Motor independence is strongly associated with the quality of life of elderly people, yet the regulators for motor aging have not been…
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Journal Article Full text
Doxifluridine promotes host longevity through bacterial metabolism
Aging is associated with alternative splicing (AS) defects that have broad implications on aging-associated disorders. However, which drug(s) can rescue age-related AS defects and extend lifespan has not been systematically explored. We performed large-scale compound screening in C. elegans using a…