32 hasil untuk "Zhou, Zhi-Rui"
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How to analyze tumor stage data in clinical research
Tumor staging serves as an important prognostic factor in cancer patient care. It also plays critical roles in cancer-related clinical research. Aimed to shed lights on how to analyze tumor staging related data and deliver proper interpretation, various statistical methods, from categorical data…
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Did dose escalated radiotherapy in stage III non-small cell lung cancer improve overall survival?
Radiotherapy has been applied in the treatment for lung cancer patients for many years, especially those with advanced stage disease who cannot be treated with surgery. However, if these advanced stage patients should be treated with standard dosage therapy (60 Gy) or high dosage therapy (>60 Gy)…
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Induction chemotherapy followed by concurrent chemoradiotherapy versus concurrent chemoradiotherapy with or without adjuvant chemotherapy for locally advanced nasopharyngeal carcinoma
This is a protocol for a Cochrane Review (Intervention). The objectives are as follows: To evaluate the efficacy and toxicity of induction chemotherapy followed by concurrent chemoradiotherapy versus concurrent chemoradiotherapy with or without adjuvant chemotherapy in locally advanced…
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Chemotherapy for newly diagnosed inoperable brain metastases from non‐small cell lung cancer
This is a protocol for a Cochrane Review (Intervention). The objectives are as follows: To assess the effectiveness of chemotherapy in patients with newly diagnosed inoperable brain metastases (BM) from non‐small cell lung cancer (NSCLC) in terms of brain response rate, overall survival (OS)…
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Highlights on molecular targets for radiosensitization of breast cancer cells: Current research status and prospects
In the past, searching for effective radiotherapy sensitization molecular targets and improving the radiation sensitivity of malignant tumors was the hot topic for the oncologists, but with little achievements. We will summarize the research results about breast cancer irradiation sensitization…
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Is internal mammary nodes irradiation as a part of breast cancer postoperative radiotherapy necessary?
Postoperative radiotherapy plays an important role in the multidisciplinary treatment of breast cancer. However, it remains a controversy whether it is necessary to carry out prophylactic internal mammary nodes irradiation (IMNI). This review will focus on this topic. In our opinion, the total risk…
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Meta-analysis of the efficacy and safety of adding an angiotensin receptor blocker (ARB) to a calcium channel blocker (CCB) following ineffective CCB monotherapy
BACKGROUND: We conducted this meta-analysis to systematically review and analyze the clinical benefits of angiotensin receptor blocker (ARB) combined with calcium channel blocker (CCB) following ineffective CCB monotherapy. METHODS: PubMed was searched for articles published until August 2015…
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Phyllodes tumors of the breast: diagnosis, treatment and prognostic factors related to recurrence
Phyllodes tumors of the breast are rare tumor types that consist of 0.3–1.0% in all breast tumors. The naming and classification of breast phyllodes tumor have been debated for years. Based on the classification criteria modified by WHO in 2003, this review mainly introduced the clinicopathologic…
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Dosimetric factors and Lyman normal-tissue complication modelling analysis for predicting radiation-induced lung injury in postoperative breast cancer radiotherapy: a prospective study
To investigate the relationship between dosimetric factors, including Lyman normal-tissue complication (NTCP) parameters and radiation-induced lung injury (RILI), in postoperative breast cancer patients treated by intensity modulated radiotherapy (IMRT). 109 breast cancer patients who received IMRT…
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Validation of different staging systems for hepatocellular carcinoma in a cohort of 249 patients undergoing radiotherapy
There is no consensus on predicting prognosis for hepatocellular carcinoma patients undergoing radiotherapy. This study aims to evaluate the validity of different staging systems. Overall, 249 hepatocellular carcinoma patients were evaluated retrospectively. All patients were classified by…
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The Definition and Delineation of the Target Area of Radiotherapy Based on the Recurrence Pattern of Glioblastoma After Temozolomide Chemoradiotherapy
Radiotherapy is an important treatment for glioblastoma (GBM), but there is no consensus on the target delineation for GBM radiotherapy. The Radiation Therapy Oncology Group (RTOG) and European Organisation for Research and Treatment of Cancer (EORTC) each have their own rules. Our center adopted a…
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Simulation of Target Tracking based on Photon-counting Laser Ranging System
As the single photon detection greatly improves the sensitivity of a traditional detector, it has enormous potentiality in distance measuring. Photon-counting laser ranging is able to extract the target's trajectory from large amounts of echo information in the case where prior information is…
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Diagnostic performance of core needle biopsy in identifying breast phyllodes tumors
BACKGROUND: A retrospective analysis of diagnoses was performed in patients with phyllodes tumors of the breast (PTB) who received preoperative core needle biopsy (CNB) and had breast surgery at Fudan University Shanghai Cancer Center from January 1, 2002 to April 1, 2013. The resulting data…
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The Efficacy and Safety of Chemotherapy in Patients With Nonsmall Cell Lung Cancer and Interstitial Lung Disease
Chemotherapy plays a critical and venturous role against the co-morbidity of nonsmall cell lung cancer and interstitial lung disease (NSCLC–ILD). We performed a Bayesian meta-analysis and systematic review to evaluate the safety and efficacy of the chemotherapy in NSCLC–ILD patients. EMBASE…
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Comparison of Short-Course Radiotherapy Versus Long-Course Radiotherapy for Treatment of Metastatic Spinal Cord Compression
In this study, we evaluate the efficacy of short-course radiotherapy (SCRT) versus long-course radiotherapy (LCRT) in the treatment of metastatic spinal cord compression (MSCC). PubMed, EMBASE, and Web of Science were searched up to April 2015. Relevant data were extracted based on inclusion and…
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A novel metabolic gene signature-based nomogram to predict overall survival in breast cancer
BACKGROUND: Breast cancer risk prediction is often based on clinicopathological characteristics despite the high heterogeneity derived from gene expression. Metabolic alteration is a hallmark of cancer, and thus, the integration of a metabolic signature with clinical parameters is necessary to…
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Comparison of Bone Mineral Density in Lumbar Spine and Fracture Rate among Eight Drugs in Treatments of Osteoporosis in Men: A Network Meta-Analysis
CONTEXT: The preferred treatment for osteoporosis in men is debated, and pairwise meta-analysis cannot obtain hierarchies of these treatments. OBJECTIVE: The objective of this study was to integrate the evidence and provide hierarchies of eight drugs based on their effect on the bone mineral…
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Development of a novel nomogram for predicting clinically significant prostate cancer with the prostate health index and multiparametric MRI
INTRODUCTION: On prostate biopsy, multiparametric magnetic resonance imaging (mpMRI) and the Prostate Health Index (PHI) have allowed prediction of clinically significant prostate cancer (csPCa). METHODS: To predict the likelihood of csPCa, we created a nomogram based on a multivariate model that…
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Short-term versus long-term hormone therapy plus radiotherapy or prostatectomy for prostate cancer: a systematic review and meta-analysis
PURPOSE: To compare the efficacy and safety of short-term versus long-term hormonotherapy (HT) plus radiotherapy (RT) or prostatectomy (RP) for prostate cancer. METHODS: Literatures were searched from Embase, PubMed, Web of science and Cochrane Library up to October, 2012. Quality of the study was…
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Building radiation-resistant model in triple-negative breast cancer to screen radioresistance-related molecular markers
BACKGROUND: To build the triple-negative breast cancer (TNBC) radiation resistance model in vitro and vivo, and screen the molecular markers that related to radiation resistance. METHODS: We used X-ray to irradiate MDA-MB-231 cells repeatedly to build radioresistant cell (231-RR), then select one…