1.440 hasil untuk "ivan"
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A Coarse-Grained Approach to Protein Design: Learning from Design to Understand Folding
Computational studies have given a great contribution in building our current understanding of the complex behavior of protein molecules; nevertheless, a complete characterization of their free energy landscape still represents a major challenge. Here, we introduce a new coarse-grained approach…
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Transferable Coarse-Grained Potential for De Novo Protein Folding and Design
Protein folding and design are major biophysical problems, the solution of which would lead to important applications especially in medicine. Here we provide evidence of how a novel parametrization of the Caterpillar model may be used for both quantitative protein design and folding. With computer…
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Schools are segregated by educational outcomes in the digital space
The Internet provides students with a unique opportunity to connect and maintain social ties with peers from other schools, irrespective of how far they are from each other. However, little is known about the real structure of such online relationships. In this paper, we investigate the structure…
Dari koleksi institusi
- Membuat model Dan Animasai TRANSFORMERSIvan c.sibero · 2009 · UNILAK
- Kinerja pegawai pada kantor balai wilayah sungai sumatera III provinsi riauRadhi ivan · 2020 · UNILAK
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Astronomical aspects of Group E-type complexes and implications for understanding ancient Maya architecture and urban planning
In the 1920s, during the first archaeological excavations at Uaxactún, Petén, Guatemala, an architectural complex named Group E was interpreted as an ancient Maya astronomical observatory, intended specifically for sighting the equinoctial and solstitial sunrises. In the following decades, a large…
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Equilibria of Idealized Confined Astral Microtubules and Coupled Spindle Poles
Positioning of the mitotic spindle through the interaction of astral microtubules with the cell boundary often determines whether the cell division will be symmetric or asymmetric. This process plays a crucial role in development. In this paper, a numerical model is presented that deals with the…
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Efficiency of Organelle Capture by Microtubules as a Function of Centrosome Nucleation Capacity: General Theory and the Special Case of Polyspermia
Transport of organelles along microtubules is essential for the cell metabolism and morphogenesis. The presented analysis derives the probability that an organelle of a given size comes in contact with the microtubule aster. The question is asked how this measure of functionality of the microtubule…
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Genetic Diversity and Structure of Dalmatian Pyrethrum ( Tanacetum cinerariifolium Trevir. /Sch./ Bip., Asteraceae) within the Balkan Refugium
Dalmatian pyrethrum (Tanacetum cinerariifolium Trevir. /Sch./ Bip.) is an outcrossing, perennial insecticidal plant, restricted to the eastern Adriatic coast (Mediterranean). Amplified fragment-length polymorphisms (AFLP) were used to investigate the genetic diversity and structure within and among…
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Adaptive and Phase Selective Spike Timing Dependent Plasticity in Synaptically Coupled Neuronal Oscillators
We consider and analyze the influence of spike-timing dependent plasticity (STDP) on homeostatic states in synaptically coupled neuronal oscillators. In contrast to conventional models of STDP in which spike-timing affects weights of synaptic connections, we consider a model of STDP in which the…
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Innate Sex Differences in the Timing of Spring Migration in a Songbird
In migrating animals protandry is the phenomenon whereby males of a species arrive at the breeding grounds earlier than females. In the present study we investigated the proximate causes of protandry in a migratory songbird, the northern wheatear Oenanthe oenanthe. Previous experiments with caged…
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Yawn Contagion and Empathy in Homo sapiens
The ability to share others' emotions, or empathy, is crucial for complex social interactions. Clinical, psychological, and neurobiological clues suggest a link between yawn contagion and empathy in humans (Homo sapiens). However, no behavioral evidence has been provided so far. We tested the…
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Confidence-Guided Local Structure Prediction with HHfrag
We present a method to assess the reliability of local structure prediction from sequence. We introduce a greedy algorithm for filtering and enrichment of dynamic fragment libraries, compiled with remote-homology detection methods such as HHfrag. After filtering false hits at each target position…
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Bonobos Protect and Console Friends and Kin
Post-conflict third-party affiliation has been reported to have different functional meanings, one of them being consolation. Here, we tested the main hypotheses that have been put forth to explain the presence of this phenomenon at a functional level in the bonobo: Self-Protection Hypothesis…
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Peace-Making in Marsupials: The First Study in the Red-Necked Wallaby ( Macropus rufogriseus )
The issue of reconciliation has been widely investigated in many eutherian mammal species. Nevertheless, no data are available for marsupial mammals. Indeed, the majority of reports focus on group dynamics from an ecological and reproductive perspective, but no study has investigated them from a…
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Reconstruction of membrane current by deconvolution and its application to membrane capacitance measurements in cardiac myocytes
Correct detection of membrane currents under whole-cell patch–clamp conditions is limited by the transfer function of a recording system. The low-pass output filter of a recording amplifier alters the time course of membrane current and causes errors in relevant descriptors. To solve these…
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Formation of homophily in academic performance: Students change their friends rather than performance
Homophily, the tendency of individuals to associate with others who share similar traits, has been identified as a major driving force in the formation and evolution of social ties. In many cases, it is not clear if homophily is the result of a socialization process, where individuals change their…
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The Season for Peace: Reconciliation in a Despotic Species ( Lemur catta )
However despotic a social group may be, managing conflicts of interest is crucial to preserve group living benefits, mainly based on cooperation. In despotic groups, post-conflict management via reconciliation (the first post-conflict reunion between former opponents) can occur, even if…
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Conserved Units of Co-Expression in Bacterial Genomes: An Evolutionary Insight into Transcriptional Regulation
Genome-wide measurements of transcriptional activity in bacteria indicate that the transcription of successive genes is strongly correlated beyond the scale of operons. Here, we analyze hundreds of bacterial genomes to identify supra-operonic segments of genes that are proximal in a large number of…
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Computational Tools for Interpreting Ion Channel pH-Dependence
Activity in many biological systems is mediated by pH, involving proton titratable groups with pKas in the relevant pH range. Experimental analysis of pH-dependence in proteins focusses on particular sidechains, often with mutagenesis of histidine, due to its pKa near to neutral pH. The key…
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Late Pleistocene-Holocene paleobiogeography of the genus Apodemus in Central Europe
Wood mice of the genus Apodemus are an essential component of small mammal communities throughout Europe. Molecular data suggest the postglacial colonization of current ranges from south European glacial refugia, different in particular species. Yet, details on the course of colonization and…
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Confidence intervals by constrained optimization—An algorithm and software package for practical identifiability analysis in systems biology
Practical identifiability of Systems Biology models has received a lot of attention in recent scientific research. It addresses the crucial question for models’ predictability: how accurately can the models’ parameters be recovered from available experimental data. The methods based on profile…
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