4 results for "Fu-Rong Li"

Role of Injured Pancreatic Extract Promotes Bone Marrow-Derived Mesenchymal Stem Cells Efficiently Differentiate into Insulin-Producing Cells

Hongbin Xie; Yunshuai Wang; Hui Zhang et al.

PLoS ONE, Vol. 8 No. 9 · 2013 · English · PLOS Scopus

Mesenchymal stem cells (MSCs) can be successfully induced to differentiate into insulin-producing cells （IPCs) by a variety of small molecules and cytokines in vitro. However, problems remain, such as low transdifferentiation efficiency and poor maturity of trans-differentiated cells. The damaged…

Correction: Penicillamine Increases Free Copper and Enhances Oxidative Stress in the Brain of Toxic Milk Mice

Ding-Bang Chen; Li Feng; Xiao-Pu Lin et al.

PLoS ONE, Vol. 7 No. 8 · 2012 · English · PLOS Scopus

Penicillamine Increases Free Copper and Enhances Oxidative Stress in the Brain of Toxic Milk Mice

Ding-Bang Chen; Li Feng; Xiao-Pu Lin et al.

PLoS ONE, Vol. 7 No. 5 · 2012 · English · PLOS Scopus

Wilson disease (WD) is characterized by the accumulation of copper arising from a mutation in the ATP7B gene. Penicillamine (PA) makes 10–50% of the patients with neurologic symptoms neurologically worse at the early stage of administration. The aim of this study was to determine how the copper…

The Immunoregulation Effect of Alpha 1-Antitrypsin Prolong β-Cell Survival after Transplantation

Yun Wang; Hong-Jie Yan; Shu-Yan Zhou et al.

PLoS ONE, Vol. 9 No. 4 · 2014 · English · PLOS Scopus

Islet transplantation has considerable potential as a cure for diabetes. However, the difficulties that arise from inflammation and the immunological rejection of transplants must be addressed for islet transplantation to be successful. Alpha 1-antitrypsin (AAT) inhibits the damage on β cells…