762 results
Showing 1–20 · 0.02 seconds · RSS
Xin yixue
ISSN 0253-9802 · Editorial Office of Journal of New Medicine · 762 articles in the index
-
Journal Article
The application of cryoneurolysis in pain management and functional rehabilitation
Cryoneurolysis (CNL), as an emerging cryotherapy technique, has demonstrated significant therapeutic effects in the rehabilitation of various diseases. By utilizing the cryogenic freezing effect, CNL effectively alleviates pain and improves muscle spasms, and helps reduce the dependence on and…
-
Journal Article
Study of the correlation between Staphylococcus aureus and epithelial-mesenchymal transition in breast cancer cells
ObjectiveTo investigate the effects and mechanisms of Staphylococcus aureus (S. aureus) infection on the growth of breast cancer cells in vitro. Methods20 strains infected by S.aureus in sterile body fluid and human triple negative-breast cancer 231 cell lines (MDA-MB-231) were collected from…
-
Journal Article
A comparative study of characteristics and influence factors of colorectal serrated lesions and traditional adenomas
ObjectiveTo explore the difference of influencing factors between colorectal serrated lesions (SLs) and traditional adenoma (TA), and to provide some reference for the prevention of two kinds of colorectal precancerous lesions. MethodsA convenient sampling method was adopted to conduct a…
-
Journal Article
Molecular mechanisms of immune response regulating hypertensive inflammatory microenvironment
Persistence of chronic low-grade inflammation is a key driver of hypertension. Molecular mechanisms such as complement molecules and inflammatory factor disorders damaging blood vessels, neuro-immune cell interactions, and immune response dysregulation aggravating target organ inflammation…
-
Journal Article
The impact of early synchronized gestures by parents with more pronounced broader autism phenotype traits on language skills of children with autism spectrum disorder
Objective To investigate the impact of broad autism phenotype (BAP) characteristics in early parent-child interactions on gesture use and the language abilities of children with Autism Spectrum Disorder (ASD) within families affected by ASD. Methods From December 2019 to December 2020, a total of…
-
Journal Article
Effect and mechanism of lificiguat on refraction in guinea pigs with lens-induced myopia
Objective To investigate the effect of lificiguat (YC-1) on refractive development in guinea pigs with lens-induced myopia (LIM). MethodsTwenty-seven 4-week-old tricolor guinea pigs were selected and divided into the LIM, LIM+YC-1, and Normal groups (n = 9 in each group). The right eyes of the LIM…
-
Journal Article
Application and considerations of minimal clinically important difference in efficacy assessment of bronchial asthma
Bronchial asthma, a significant chronic condition, poses a substantial threat to global public health, with a rising number of clinical studies dedicated to understanding this disease. In the analysis of the outcomes of these studies, it is crucial to consider not just statistical significance but…
-
Journal Article
Optimization of imaging parameters and structural imaging evaluation of ICG in peripheral neuroimaging of rats
Objective To explore the appropriate imaging dose-time combination （ADTC）of indocyanine green（ICG）for peripheral nerve imaging in rats using near-infrared fluorescence imaging（NIRF）technology, and to analyze the structural fidelity and resolution efficiency of neuroimaging under this ADTC strategy…
-
Journal Article
Analysis of clinical characteristics and spectrum of causative drugs in 135 patients with drug eruptions
Objective To investigate the causative drugs, clinical characteristics, and prognostic factors of drug eruptions, and to provide evidence for clinical diagnosis, management, and risk assessment. Methods A retrospective analysis was conducted on 135 patients with drug eruptions who were hospitalized…
-
Journal Article
Effect of frailty on acute exacerbation readmission and all-cause mortality of hospitalized elderly patients with heart failure
ObjectiveTo investigate the incidence of frailty in elderly patients with heart failure(HF) and the impact of frailty on their acute exacerbation readmission and all-cause mortality. MethodsElderly patients with HF, aged 60-80 years, who were hospitalized in the First Affiliated Hospital of the…
-
Journal Article
Construction of a family empowerment intervention program for children with autism spectrum disorder based on the TTM theory
ObjectiveTo construct a family empowerment intervention program for children with autism spectrum disorder (ASD) based on the transtheoretical model (TTM) of behavior change, focusing on the core concept of family empowerment and emphasizing the discovery of children's strengths and the cultivation…
-
Journal Article
Subglottic positive pressure technology and its application in coordinated multifunctional rehabilitation of patients undergoing tracheotomy
As a key treatment for critically ill patients, tracheotomy can effectively maintain airway patency, whereas may change the anatomical structure of the upper respiratory tract and weaken the defense function, often causing multiple dysfunctions in breathing, swallowing and speech and seriously…
-
Journal Article
Ultrasound habitat radiomics fusion model for predicting lymph node metastasis of papillary thyroid carcinoma
ObjectiveTo construct a multimodal fusion model integrating ultrasound habitat radiomics features, clinical parameters, and immunological markers for preoperative assessment of central lymph node metastasis (CLNM) risk in clinically node-negative (cN0) papillary thyroid carcinoma (PTC) patients…
-
Journal Article
Nomogram prediction model for disease-free survival in hepatocellular carcinoma patients based on clinical data and miR-497-5p expression level
ObjectiveTo investigate the prognostic factors of hepatocellular carcinoma (HCC) and develop a Nomogram prediction model based on clinical data and miR-497-5p expression levels to improve disease-free survival (DFS) after surgery. MethodsThis study utilized the GSE31384 dataset (comprising miRNA…
-
Journal Article
Association between gender difference and postoperative recurrence risk of complete rectal prolapse: a real-world cohort study
ObjectiveTo investigate the association between gender difference and postoperative recurrence risk of complete rectal prolapse (CRP), and to provide a scientific basis for gender-specific management of clinical prognosis. MethodsIn this retrospective cohort study, 180 CRP patients who underwent…
-
Journal Article
Study on the mechanism of YinYang Gongji Pill in inducing pyroptosis of hepatoma carcinoma cells via the caspase-3/GSDME pathway
ObjectiveTo investigate the mechanism by which YinYang Gongji Pill (YYGJ) induces pyroptosis in hepatocellular carcinoma cells. MethodsNetwork pharmacology was employed to analyze the potential targets and mechanisms of YYGJ in the treatment of hepatocellular carcinoma. Molecular docking was…
-
Journal Article
Construction of MOV nanoparticles to improve allergic airway diseases by restoring airway immunomodulatory function
Objective To construct a nanoparticle-based carrier capable of restoring airway immunoregulatory function under allergic conditions, and evaluate its immunomodulatory effects and potential therapeutic value against allergic airway inflammation. Methods Vasoactive intestinal peptide (VIP)-loaded…
-
Journal Article
Developing an objective evaluation system based on cytokine profile in nasal secretions for allergic rhinitis treatment outcomes: a scoping review
Objective To analyze the characteristics of cytokine profile changes in nasal secretions of allergic rhinitis (AR)patients receiving different treatments, with the aim of informing an objective, biomarker-based system for clinical efficacy assessment and guiding future research and policy…
-
Journal Article
Analysis of factors influencing delays in seeking medical care among patients with hepatitis B virus-associated hepatocellular carcinoma
Objective To explore the delay in seeking medical care and its influencing factors among patients with hepatitis B virus (HBV)-associated hepatocellular carcinoma. Methods Clinical data of 285 HBV-associated hepatocellular carcinoma (HCC) patients who were treated in the Department of Hepatobiliary…
-
Journal Article
Intestinal stoma for low rectal cancer: current status and future perspectives
The technique of intestinal stoma formation plays a critical role in determining postoperative recovery and long-term quality of life for patients with low rectal cancer, making its appropriate application a vital component of surgical treatment. This article systematically reviews the…