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Annals of Saudi Medicine
Scopus
ISSN 0256-4947 · King Faisal Specialist Hospital and Research Centre · 1,841 articles in the index
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Journal Article
Acute exacerbation of chronic rhinosinusitis: clinical and microbiological perspectives from a Saudi tertiary care center
BACKGROUND: Acute exacerbations of chronic rhinosinusitis (AECRS) are increasingly recognized as a distinct clinical entity that significantly impacts quality of life. Despite its clinical relevance, data on its prevalence, clinical characteristics, and underlying bacteriology remain limited…
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Journal Article
Epidemiology and risk factors of colorectal polyp detection: a regional, single-center retrospective study
BACKGROUND: Colorectal polyps are the most important precursor lesions of colorectal cancer. Their epidemiological characteristics and risk factors exhibit substantial regional and population-based variations. Qinghai Province, located on the Qinghai–Tibet Plateau in China, is characterized by a…
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Journal Article
Age-related patterns in hysterectomy: indications and surgical route selection in a three-year tertiary-center cohort
BACKGROUND: Hysterectomy indications and surgical route selection may vary with age due to shifting case mix. OBJECTIVES: To describe age-stratified hysterectomy indications and routes and identify factors independently associated with route selection. DESIGN: Retrospective chart review SETTINGS…
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Journal Article
Association between proton pump inhibitor use and vitamin B12 deficiency: a retrospective cohort study in primary care centers in Riyadh, Saudi Arabia
BACKGROUND: Proton pump inhibitors (PPIs) are widely prescribed, yet their long-term effects on vitamin B12 status remain debated with inconsistent findings across studies. Data from Saudi Arabia and the Middle Eastern primary-care context are limited. OBJECTIVES: To evaluate changes in serum…
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Journal Article
Diagnostic utility and limitations of CT-guided transthoracic fine-needle aspiration biopsy in Lung-RADS 4 pulmonary nodules ≤2 cm
BACKGROUND: Managing small Lung-RADS 4 pulmonary nodules is clinically challenging. While CT-guided TTFNAB is standard, its efficacy and safety for lesions ≤2 cm require further evaluation to optimize outcomes and reduce unnecessary surgeries. OBJECTIVES: This study aimed to evaluate the diagnostic…
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Journal Article
Establishment and validation of reference intervals for the neutrophil CD64 index in a healthy adult population from Guangxi, China
BACKGROUND: The neutrophil CD64 (nCD64) index is a potent biomarker for infectious diseases; however, the lack of standardized reference intervals (RIs) limits its clinical utility. OBJECTIVES: This study aimed to establish and validate reference intervals (RIs) for the nCD64 index specifically for…
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Journal Article
Comparative overall survival in T4N0 and T2-3N1 non-metastatic colon cancer: a retrospective cohort study
BACKGROUND: The prognostic significance of pathological T stage relative to nodal involvement in colon cancer remains controversial. Emerging evidence suggests that patients with T4N0 disease may experience outcomes comparable to or worse than those with node-positive disease. OBJECTIVES: This…
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Journal Article
Endotracheal tube size selection in critically ill patients: a 4-year single-center experience in Saudi Arabia
BACKGROUND: Intubation is a critical aspect of airway management and supportive care for intensive care unit (ICU) patients. Inappropriate size of endotracheal tubes (ETT) affects the patient's airway, it is crucial to choose an appropriate size for each patient. OBJECTIVES: This study aimed to…
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Journal Article
Biochemical pregnancy outcomes following dual versus human chorionic gonadotropin-only trigger in gonadotropin-stimulated intrauterine insemination cycles for unexplained infertility: a retrospective cohort study
BACKGROUND: Unexplained infertility remains a diagnostic and therapeutic challenge. Dual trigger, combining gonadotropin-releasing hormone (GnRH) agonist and human chorionic gonadotropin (hCG), has been proposed to more closely mimic the physiological mid-cycle gonadotropin surge than hCG alone in…
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Journal Article
Clinical characteristics of lung cancer in never-smokers: a multicenter Saudi cohort
BACKGROUND: Lung cancer in never-smokers represents a distinct clinical and biologic entity. However, its epidemiologic characteristics remain incompletely described in the Middle East. OBJECTIVES: To characterize lung cancer in never-smokers and compare it with ever-smokers in a multicenter Saudi…
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Journal Article
Sialendoscopy in the management of obstructive sialadenitis: clinical experience and treatment outcomes
BACKGROUND: Obstructive sialadenitis is a common salivary gland disorder. This retrospective study evaluated the outcomes of sialendoscopy in 90 patients treated between July 2018 and December 2023. OBJECTIVE: To evaluate the success rate, complications, and predictors of treatment outcomes of…
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Journal Article
Maternal oral glucose tolerance test parameters and neonatal hearing screening outcomes: a retrospective cohort study
BACKGROUND: Gestational diabetes mellitus (GDM) has been associated with adverse pregnancy outcomes and may influence fetal neurosensory development, particularly auditory function. However, evidence regarding its effect on neonatal hearing screening remains inconsistent. OBJECTIVES: To evaluate…
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Journal Article
Determinants of hospitalization among Indonesian Hajj pilgrims in Saudi Arabia: a nationwide retrospective cohort study
BACKGROUND: The Hajj pilgrimage is a major global gathering that poses health challenges, particularly for those with pre-existing health conditions that require hospitalization. OBJECTIVES: To examine the determinants of hospitalization among Indonesian Hajj pilgrims and quantify their relative…
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Journal Article
Ramadan fasting is associated with reduced penetrating trauma and increased peptic ulcer perforation: a 10-year retrospective analysis
BACKGROUND: Ramadan fasting alters neuroendocrine rhythms, nocturnal gastric acid secretion, and population-level social behaviour. Its concurrent impact on acute gastrointestinal complications and on community-level violent trauma in high-volume urban settings remains poorly quantified…
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Journal Article
The proportion of GBS-positive mothers among the screened population and outcomes of maternal Group B streptococcus colonization at King Saud University Medical City: a retrospective cohort study
BACKGROUND: Group B Streptococcus (GBS) is a leading cause of neonatal morbidity, preventable via intrapartum antibiotic prophylaxis (IAP). OBJECTIVE: To determine the proportion of GBS-positive mothers among the screened population, evaluate IAP protocol adherence, and identify clinical risk…
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Journal Article
Real-world outcomes of T cell lymphoma in a tertiary cancer center in Saudi Arabia
BACKGROUND: T-cell and natural-killer (T/NK)–cell lymphomas are rare and aggressive malignancies. Prior to our study, no dedicated institutional survival analyses of T/NK-cell lymphomas had been published from Saudi Arabia. OBJECTIVES: To evaluate the clinical characteristics, prognostic factors…
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Journal Article
Genetic analysis and clinical phenotype of pulmonary arterial hypertension in an Algerian population
BACKGROUND: Pulmonary arterial hypertension (PAH) involves progressive obstruction of small pulmonary vessels due to vascular remodeling. Although the genetic architecture of PAH is increasingly understood, it remains poorly characterized in Algeria due to limited studies and the absence of…
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Journal Article
Safety and heterogeneity of mRNA-based seasonal Influenza vaccines: A systematic review and meta-analysis of randomized controlled trials
BACKGROUND: Messenger RNA (mRNA)-based influenza vaccines represent a promising advancement in seasonal influenza prevention. However, comprehensive evaluation of their serious safety profile is essential as these vaccines progress toward widespread clinical use. While individual randomized…
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