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International Journal of Hyperthermia
Scopus
ISSN 0265-6736 · Taylor & Francis Group · 1,193 articles in the index
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Journal Article
Heat-activated intravenous liposomal doxorubicin combined with mitomycin C hyperthermic intravesical chemotherapy (HIVEC) for treatment of bladder cancer
Purpose To evaluate the safety and pharmacokinetics of lyso-thermosensitive liposomal doxorubicin (LTLD, ThermoDox®) combined with mitomycin C (MMC) hyperthermic intravesical chemotherapy (HIVEC) as a potential treatment for non-muscle invasive bladder cancer.Materials and methods Four healthy…
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Journal Article
2024 International expert consensus on ultrasound-guided thermal ablation for secondary and tertiary hyperparathyroidism
Objective Treatments for secondary and tertiary hyperparathyroidism (SHPT/THPT) remain significant challenges in patients with end-stage renal disease.Methods Thermal ablation (TA) has emerged as a minimally invasive, safe, and effective alternative to surgical resection (SR). However, technical…
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Journal Article
Clinical efficacy and safety of cervical pregnancy treated with high-intensity focused ultrasound versus uterine artery embolization prior to ultrasound-guided suction curettage: a retrospective study
Objective This study aimed to retrospectively evaluate the efficacy and safety of high-intensity focused ultrasound (HIFU) versus uterine artery embolization (UAE) as pretreatment prior to ultrasound-guided suction curettage in the management of cervical pregnancy.Methods A retrospective review was…
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Journal Article
Subharmonics are not an infallible safety metric for cavitation dynamics
Objective There has been a substantial increase in the range of applications for focused ultrasound in recent years with multiple clinical trials reporting promising results. Reliable treatment monitoring protocols will be essential for future clinical development of these therapies. Acoustic…
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Journal Article
Survival and morbidity in elderly patients treated with cytoreductive surgery and HIPEC for colorectal peritoneal metastases: a population-based study
Objective Cytoreductive surgery with hyperthermic intraperitoneal chemotherapy (CRS-HIPEC) has improved outcomes in colorectal cancer (CRC) patients with peritoneal metastases (PM), yet evidence regarding perioperative risk and long-term survival in those 75 years or older remains uncertain. The…
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Journal Article
Efficacy and safety of microwave ablation for the treatment of pulmonary osteosarcoma oligometastases
Purpose Evaluate efficacy and safety of microwave ablation (MWA) for pulmonary osteosarcoma oligometastases.Methods Twenty-two patients (median age, 16 years [range, 9–41 years]; 15 male) with pulmonary osteosarcoma oligometastases who underwent MWA from January 2018 to December 2023 were included…
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Journal Article
Nomogram for predicting HIFU efficacy in uterine fibroids: based on oxytocin-induced arterial-phase perfusion delay and ultrasound features
Purpose This study aimed to develop and validate a nomogram for predicting high-intensity focused ultrasound (HIFU) ablation efficacy in uterine fibroids, based on the Oxytocin-Induced Arterial-phase Perfusion Delay Time(APDT) on contrast-enhanced ultrasound (CEUS), combined with ultrasound…
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Journal Article
Expanding the role of thermal ablation in thyroid cancer beyond low-risk unifocal PTMC: a review of the current state and future perspectives
Background Thermal ablation (TA) is an established treatment for low-risk unifocal papillary thyroid microcarcinoma (PTMC) and has been incorporated into several clinical guidelines. However, its clinical indications remain limited and do not fully encompass more advanced tumor stages, multifocal…
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Journal Article
Injectable radiopaque targets for cone-beam CT guided histotripsy
Background Cone-beam CT (CBCT) guided histotripsy is being developed as a supplemental image guidance technique for histotripsy. The goal of this work is to present a percutaneously injectable, radiopaque target that can be used in preclinical testing of CBCT-guided histotripsy.Methods Livers of…
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Journal Article
Modified tumor uptake and biodistribution of nanoparticles coated with small extracellular vesicle membranes derived from distinct tumor cell lines
Background Targeting tumors with nanoparticles can significantly improve the anti-tumor effect of thermal treatments while sparing normal tissue from nonspecific effects. The surface coating is essential to driving the biological fate of nanomaterials. Exosomes, a type of long-circulating secreted…
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Journal Article
Impact of breast biopsy markers on magnetic resonance-guided focused ultrasound
Background The placement of a biopsy marker at the time of breast biopsy is standard of care to mark the biopsy site and facilitate surgical excision. However, their impact on incisionless treatments like magnetic resonance-guided focused ultrasound remains underexplored. These factors are…
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Journal Article
Automated subcutaneous fat segmentation with a convolutional neural network in magnetic resonance guided high-intensity focused ultrasound treatment for uterine fibroids
Introduction In MR-guided high-intensity focused ultrasound (MR-HIFU) treatment for uterine fibroids, the subcutaneous abdominal fat layer is prone to unwanted heating, especially during consecutive sonications. Automating its delineation with a deep learning algorithm would enhance treatment…
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Journal Article
Multimodal MRI radiomics for predicting HIFU ablation efficacy in uterine fibroids: a machine learning study
Objective To explore the predictive value of machine learning-based multimodal MRI radiomics combined with clinical features in the efficacy of high-intensity focused ultrasound (HIFU) ablation of uterine fibroids.Methods This study included 390 patients with uterine fibroids who underwent HIFU…
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Journal Article
Feasibility of thermal dose painting during magnetic nanoparticle thermal therapy: a computational analysis
Background Spatially confined magnetic nanoparticle thermal therapy (SC-MNTT) can improve the tumor coverage index (CI) when the magnetic field-free region (FFR) is manually steered. However, static steering demands significant time and expertise from experienced control engineers during treatment…
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Journal Article
Incomplete thermal ablation accelerates local and systemic tumor progression in an immunocompetent prostate cancer model
Background This study aims to evaluate the effects of sublethal hyperthermia on tumor growth of residual tumors in an immune-competent mouse model of prostate cancer.Materials and Methods The study progressed through sequential experiments to assess the effects of incomplete thermal ablation…
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Journal Article
Retrospective multicenter study of thermal ablation outcomes in subcapsular versus intraparenchymal papillary thyroid microcarcinoma
Objective To evaluate the clinical outcomes of thermal ablation (TA) for subcapsular papillary thyroid microcarcinoma (PTMC) and compared them with those of intraparenchymal PTMC.Methods Patients with unifocal, clinical node-negative PTMC who underwent TA at three institutions between July 2015 and…
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Journal Article
Enhancing patient selection for thyroid thermal ablation: insights from a multidisciplinary team approach
Introduction Thermal ablation (TA) is increasingly used to treat benign thyroid nodules; however, a residual risk of occult malignancy persists despite two benign cytology results. We aimed to: (1) evaluate the proportion of non-benign histological results among patients excluded from TA during…
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Journal Article
Perfusion response to treatment outcome: CEUS links oxytocin to HIFU efficacy prediction for uterine fibroids
Objectives To evaluate oxytocin-induced perfusion changes in uterine fibroids using contrast-enhanced ultrasound(CEUS) and determine their predictive value for high-intensity focused ultrasound (HIFU) ablation efficacy.Methods Fifty-five patients (mean age 42.15 ± 5.34 years). with 78 uterine…
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