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Turkish Journal of Hematology
Scopus
ISSN 1300-7777 · Turkish Society of Hematology · 1.564 artikel di indeks
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Artikel Jurnal
Clinical and Prognostic Features of Erythrodermic Cutaneous T-Cell Lymphoma: A Retrospective Study of 35 Patients
Objective: Erythrodermic cutaneous T-cell lymphomas (E-CTCLs), including erythrodermic mycosis fungoides (E-MF) and Sezary syndrome (SS), are aggressive and rare variants of CTCL with overlapping clinical and pathological features. Differentiating between E-MF and SS is often challenging due to…
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Artikel Jurnal
Salvage Treatment Options for Posttransplant Relapse in Children with Early/Very Early Relapse of Acute Lymphoblastic Leukemia: A Single-Center Experience
This study aimed to evaluate salvage treatment options for posttransplant relapse in children with early/very early relapse of acute lymphoblastic leukemia (ALL). Forty consecutive high-risk ALL cases were divided into two groups based on the salvage treatment for posttransplant relapse: Group 1…
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Artikel Jurnal
The Unique Impact of the Atomic Bomb on Modern Hematology
On August 6, 1945, the United States dropped the first atomic bomb ('Little Boy') on Hiroshima, and on August 9, 1945, it dropped the second atomic bomb ('Fat Man') on Nagasaki. Two Canadian scientists, Ernest A. McCulloch and James E. Till, developed the spleen colony method in the 1960s based on…
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Artikel Jurnal
Primary Hemophagocytic Lymphohistiocytosis: A Severe Immune Dysregulatory Disease with Various Genotypic Features and Outcomes: A Cross-Sectional Study from a Tertiary Pediatric Center
Objective: Inborn errors of immunity (IEIs) are caused by deficiencies or functional abnormalities in the immune system, leading to increased susceptibility to infections, autoimmunity, autoinflammatory diseases, allergies, and/or malignancies. Primary hemophagocytic lymphohistiocytosis (HLH)…
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Artikel Jurnal
IGF2BP3 Promoted the Overproliferation of AML Cells via Stability of NRXN2 mRNA
Objective: Acute myeloid leukemia (AML) is a malignant tumor with high incidence and mortality. This study aimed to investigate whether insulin-like growth factor 2 mRNA-binding protein 3 (IGF2BP3) regulates the stability of neurexin 2 (NRXN2) mRNA in an N6-methyladenosine (m6A)-dependent manner…
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Artikel Jurnal
Expression of Immune Checkpoints LAG-3, CTLA-4, TIM-3, and PD-1 in Beta-Thalassemia Patients Treated Using HbF Augmentation Therapy and Regular Transfusions
Objective: Beta-thalassemia is an inherited hemoglobin disorder caused by mutations in the HBB gene encoding beta-globin chains. Severe anemia secondary to defective globin chains, chronic hemolysis, and ineffective erythropoiesis necessitate transfusion support from early childhood. Recently used…
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Artikel Jurnal
2025 Update of Cellular Immunotherapy for Plasma Cell Disorders
Despite progression-free survival in multiple myeloma (MM) patients extending to 17 years due to contemporary quadruplet induction therapies, there remains a necessity for novel products in the treatment of high-risk patients. BCMA, GPRC5D, FcRH5, SLAMF7, and TACI are the principal chimeric antigen…
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