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Biotechnology & Biotechnological Equipment
Scopus
ISSN 1310-2818 · Taylor & Francis Group · 1.340 artikel di indeks
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Artikel Jurnal
Genome-wide characterization and expression analysis of the YUCCA genes in castor (Ricinus Communis L.)
Auxin plays an essential role in all stages of plant growth and development. Castor (Ricinus communis L.) is an important oil and bioenergy crop with substantial potential. However, few studies have been conducted on auxin in castor, and the endogenous auxin synthesis process in this plant remains…
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Artikel Jurnal
Culture medium optimization and active compounds investigation of an anti-quorum sensing marine-derived actinomycete Streptomyces chumphonensis HN2-56
Quorum sensing inhibitors (QSIs) can inhibit the quorum sensing regulated physiological functions of bacteria and might be useful in drug-resistant bacterial infection therapy. The culture medium of a mangrove derived actinobacterium Streptomyces chumphonensis HN2-56, which exhibiting higher…
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Mechanism of enhanced ectoine production in engineered Escherichia coli investigated through integrated metabolomic and transcriptomic analyses
Ectoine, a compatible solute and valuable cosmetic additive, is synthesized from L-aspartate-β-semialdehyde (ASA) via a three-step pathway catalyzed by EctABC. To investigate the metabolic basis of ectoine overproduction in an engineered E. coli strain E2, we employed an integrated analysis of…
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Artikel Jurnal
Mechanism of hydraulic shear generation in activated sludge reactors, its impact on sludge cultivation, and the evolution of quantitative expression methods
Hydraulic shear has a significant impact on the formation, morphology, and properties of flocs and granular sludge in activated sludge reactors, making it a key parameter in related research. This paper first analyzes the microscopic mechanisms of hydraulic shear generation from the perspective of…
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Comparative transcriptome analysis revealed the molecular mechanism response to salt stress at the seedling stage in hexaploid triticale (× Triticosecale Wittmack)
Hexaploid triticale (×Triticosecale Wittmack), a grain-forage crop, exhibits outstanding stress tolerance and adapts well to the saline soils of the Qaidam Basin in Qinghai Province, China. In this study, we conducted comparative analyses of transcriptomic, phenotypic, and biochemical responses in…
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Identification of compounds with regenerative effects in the mucus of the garden snail Cornu aspersum
Snail mucus is a complex multicomponent mixture of proteoglycans, glycosaminoglycans, enzymes, hyaluronic acid, proteins, antimicrobial peptides, amino acids and metal ions. This study presents the chemical and mineral composition of mucus from the garden snail Cornu aspersum and the effectiveness…
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Comparative analysis of prices, public expenditures, and utilization of biological disease modifying drugs for treatment of inflammatory joint diseases in Bulgaria and Serbia
The inflammatory joint diseases are characterized by high prevalence rates and significant burdens in both Bulgaria and Serbia. Regional differences in pricing policy might influence access to therapy. The goal of our study is to compare and analyze the prices, public spending, and utilization of…
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Artikel Jurnal
Antibacterial efficacy of cinnamon bark essential oil against multi-resistant Enterococci using LEGO® MINDSTORMS®-based automated sterilization equipment
The LEGO® coding platform, widely used in education for its modularity and accessibility, has had limited application in laboratory automation. To address limitations of conventional disk diffusion methods, this study developed an automated flame sterilization and inoculation system using LEGO®…
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Simplified MS2 phage-like particle production including a novel maturation protein internal fusion affinity tag
Phage-like particles (PLPs) are fabricated self-assembling nanoparticles derived from the structural elements of bacteriophages. These particles have biotechnological utility because of the ability to easily modify surface chemistry and compartmentalize nucleic acids or other materials. A…
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Artikel Jurnal
Antibacterial potential of Piper nigrum L. essential oil targeting FtsZ, GyrB, murA, and PTP proteins: in silico study
Piper nigrum or black pepper, is renowned for its medicinal properties and widespread use as a spice. Its essential oil, rich in active compounds, holds promise for combating bacterial contamination, particularly in food and beverages. This study analyzed the antibacterial potential of black pepper…
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Artikel Jurnal
Impact on COVID-19 pandemic on children immunization coverage in Bulgaria
The primary focus of health systems on containing the COVID-19 epidemic impedes access to health care for society’s most vulnerable segments, particularly children. For years, Bulgaria experienced a decline in mandatory vaccine coverage in children, especially for measles, mumps and rubella. The…
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Artikel Jurnal
35 blood and urine biomarkers in Polycystic Kidney Disease: a bidirectional Mendelian randomization study
Polycystic Kidney Disease (PKD), a highly prevalent hereditary condition, presents significant gaps in understanding its early-stage pathophysiology and lacks reliable biomarkers to capture these early mechanistic changes. In this investigation, we leveraged a bidirectional Mendelian…
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Artikel Jurnal
Evidence for a newly discovered triallelic pattern in the human STR D1S1656 locus
In this study, we report a case of a previously undetected triallelic pattern in the arrangement of structures at the D1S1656 locus in the Bulgarian population. The D1S1656 locus is one of the most widely used targets, present in almost all genetic analyses of DNA in forensic medical examinations…
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Artikel Jurnal
Safety profiles of biosimilars vs. their EU reference products: INNs (adalimumab, bevacizumab, trastuzumab, rituximab, infliximab, etanercept)
This study evaluates the safety profiles of biosimilar medicinal products (MPs) compared to their reference counterparts within the European Union (EU). Biosimilars, cost-effective alternatives to original biologics, enhance patient access to vital treatments. Despite their similarity to reference…
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Artikel Jurnal
Comparative analysis of retrosynthesis applications for predicting of pathways for plant Secondary metabolite production
Secondary metabolites (SMs), organic compounds synthesized by plants, play crucial roles in their own physiology and within their ecological niches, and have extensive usages in industries like pharmaceuticals, cosmetics, and food. Due to the complex nature of these metabolites, utilizing…
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Artikel Jurnal
Genetic modifications to push L-tyrosine synthesis in Escherichia coli
L-tyrosine, an aromatic amino acid, has attracted increasing attention owing to its wide application in industrial settings. Nonetheless, to obtain strains with high efficiency in producing L-tyrosine still faces challenges. In this study, a recombinant bacteria with the ability to accumulate…
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Artikel Jurnal
Enhancing the nutritional values of tiger nut meal through solid-state fermentation
Tiger nut (Cyperus esculentus L.) is widely recognized as both an oil crop and a high-quality forage. However, the comprehensive utilization of tiger nut meal (TNM) remains underexplored. This study investigates the potential of solid-state fermentation with selected microorganisms to convert TNM…
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Artikel Jurnal
The effect of metformin on serum FABP4 and PPARγ levels in patients with type 2 diabetes + nonalcoholic fatty liver disease
This prospective observational study, conducted at the Affiliated Hospital of Inner Mongolia Medical University, aimed to investigate the effects of metformin on serum Fatty acid-binding protein 4 (FABP4) and Peroxisome Proliferator-activated receptor γ (PPARγ) levels in patients with Type 2…
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Artikel Jurnal
Sperm imaging utilizing terahertz near-field scanning microscopy
Terahertz (THz)-based near-field imaging technology exhibits significant potential for applications in biomedical detection. This study investigates biological cells utilizing the rapid imaging capabilities, high resolution, and non-destructive characteristics inherent to terahertz scattering-based…
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Artikel Jurnal
Chemical composition, antimicrobial and anticancer activities of Paederia lanuginosa WALL
Paederia lanuginosa WALL. (P. lanuginosa) is a medicinal herb used to treat leprosy, expel worms, detoxify the body, and address stomach-related illnesses. On the other hand, P. lanuginosa leaves can also be used as a culinary spice. This study investigates the chemical composition of P. lanuginosa…
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