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Journal

Journal of Innovative Optical Health Sciences

Scopus

ISSN 1793-5458 · World Scientific Publishing · 865 articles in the index

  1. Journal Article

    Multi-modal retinal disease diagnosis based on fundus photography and OCT images

    Han Xu; Ruichan Lv

    Journal of Innovative Optical Health Sciences, Vol. 19 No. 02 · 2026 · English · DOAJ Scopus

    Retinal diseases are a serious threat to human visual health and their early diagnosis is crucial. Currently, most of the retinal disease diagnostic algorithms are based on a single imaging modality of fundus color photography (FCP) or optical coherence tomography (OCT). These methods can only…

  2. Journal Article

    Fabrication of silicone vascular phantoms using chewy candy as a dissolvable core material: Feasibility study

    Hyunseon Yu; Chanyoung Kim; Donghwan Ko et al.

    Journal of Innovative Optical Health Sciences, Vol. 19 No. 02 · 2026 · English · DOAJ Scopus

    This study aims to develop a novel, cost-effective method for fabricating silicone vascular phantoms (SVPs) using “chewy candy” as a dissolvable core material. The study explores the feasibility of using chewy candy to create detailed and intricate vascular models for clinical applications. The…

  3. Journal Article

    Research on tissue section negative detection algorithm based on multispectral microscopic imaging

    Cheng Wang; Qian-Qian Ge; Ru-Juan Wu et al.

    Journal of Innovative Optical Health Sciences, Vol. 19 No. 02 · 2026 · English · DOAJ Scopus

    In recent years, the rapid advancement of artificial intelligence (AI) technology has enabled AI-assisted negative screening to significantly enhance physicians’ efficiency through image feature analysis and multimodal data modeling, allowing them to focus more on diagnosing positive cases…

  4. Journal Article

    Applications of novel optical imaging methods in the study of marine mollusks: A review

    Deliang Yu; Changjiang Li; Zhen Lu et al.

    Journal of Innovative Optical Health Sciences, Vol. 19 No. 02 · 2026 · English · DOAJ Scopus

    Optical imaging has been pivotal in biological research (e.g., cellular/developmental biology) for over two centuries. Recent advances like super-resolution fluorescence and nonlinear optical microscopy enable nanoscale studies of live cells and animals, yet their application to marine mollusks —…

  5. Journal Article

    Orientation- and wavelength-dependent sperm motility in optical trapping

    Juan Wang; Jifu Lyu; Haoyu Pan et al.

    Journal of Innovative Optical Health Sciences, Vol. 19 No. 02 · 2026 · English · DOAJ Scopus

    Optical tweezers technology has the characteristics of noncontact manipulation in three dimensions and steerable separation in solutions, and could be applied to obtain a separated sperm with high quality for intracytoplasmic sperm injection (ICSI). However, the effects of optical tweezers on sperm…

  6. Journal Article

    Phototherapy for insomnia disorder: Systematic review and meta-analysis

    Tianyi Zhou; Yangyi Zhang; Na Li et al.

    Journal of Innovative Optical Health Sciences, Vol. 19 No. 02 · 2026 · English · DOAJ Scopus

    Insomnia disorder negatively affects the quality of life of patients. Phototherapy has proven effective in treating sleep problems. This study aimed to summarize the impact of phototherapy on sleep quality in patients with insomnia disorder and the factors influencing its effectiveness. We followed…

  7. Journal Article

    Photoacoustic imaging and main lobe width analysis for enhancing microwave ablation monitoring of liver tissue

    Min Wan; Yameng Zhang; Shihao Tang et al.

    Journal of Innovative Optical Health Sciences, Vol. 19 No. 02 · 2026 · English · DOAJ Scopus

    Microwave ablation (MWA) is a minimally invasive technique for treating hepatic tumors, necessitating precise monitoring to ensure treatment efficacy and minimize damage to surrounding tissues. This study explores the potential of photoacoustic imaging (PAI) in monitoring MWA by examining ex vivo…

  8. Journal Article

    Evaluation of tooth physiological characteristics based on PS-OCT

    Songwen Xu; Weike Wang; Di Yang et al.

    Journal of Innovative Optical Health Sciences, Vol. 19 No. 02 · 2026 · English · DOAJ Scopus

    Accurate and early evaluation of dental physiological characteristics is essential for effective disease detection and management. Polarization-sensitive optical coherence tomography (PS-OCT) is a noninvasive high-resolution imaging technique that can obtain tooth structure and physiological…

  9. Journal Article

    Traction force microscopy: Bridging cytology and mechanics through optics

    Ming Liu; Xuefei Chen; Bo Jiang et al.

    Journal of Innovative Optical Health Sciences, Vol. 19 No. 02 · 2026 · English · DOAJ Scopus

    Cells interact with the extracellular matrix and generate traction forces, which play fundamental roles in many cytological activities, such as migration and differentiation. The quantification of these traction forces is a prerequisite for understanding the interaction and regulation between force…

  10. Journal Article

    Detection of vitreoretinal interface abnormalities from OCT images based on DS-YOLOv7 network

    Xin Zhou; Ying Fan; Gaowei Li et al.

    Journal of Innovative Optical Health Sciences, Vol. 19 No. 02 · 2026 · English · DOAJ Scopus

    Advances in optical coherence tomography (OCT) technology allow a clear view of the vitreoretinal interface (VRI). The abnormality of the VRI is one of the common symptoms of high myopia, mainly including posterior vitreous detachment (PVD) and epiretinal membrane (ERM). They can cause severe…

  11. Journal Article

    Optical coherence tomography for surgical demarcation of GI tumor margins for accelerated decision-making during the surgical resection of tumors

    Mohamed Nijas Veluthedath; Anuradha Sekaran; Manjoosha R Yerrapragada et al.

    Journal of Innovative Optical Health Sciences, Vol. 19 No. 02 · 2026 · English · DOAJ Scopus

    Gastric cancer, including stomach tumors, poses significant health challenges due to late-stage diagnosis and limited early detection methods. Accurate imaging and precise tumor margin demarcation are critical for effective treatment planning and improved patient outcomes. Conventional imaging…

  12. Journal Article

    Two-step thermocompression bonding of High-NA-compatible glass microfluidic chips for imaging flow cytometry

    Lingqi Jiang; Yong Han; Lei Gao et al.

    Journal of Innovative Optical Health Sciences, Vol. 19 No. 05 · 2026 · English · DOAJ Scopus

    Imaging flow cytometry is rapidly developing toward higher spatial resolution and enhanced capability for resolving subcellular structures, which makes such systems increasingly dependent on high-numerical-aperture objectives for higher-resolution imaging, thereby imposing higher requirements on…

  13. Journal Article

    Label-free lipid droplet imaging for rapid nonalcoholic-fatty-liver-disease (NAFLD) analysis using dynamic full-field optical coherence tomography

    Xiaobo Qin; Ming Yan; Yanting Wu et al.

    Journal of Innovative Optical Health Sciences, Vol. 19 No. 05 · 2026 · English · DOAJ Scopus

    Nonalcoholic fatty liver disease (NAFLD) is one of the most prevalent chronic liver diseases globally. Hepatic steatosis, characterized by the accumulation of lipid droplets (LDs), is a hallmark of NAFLD. Traditional pathology and specific fluorescent dye imaging have difficulty in observing LDs in…

  14. Journal Article

    The effectiveness of photobiomodulation of the brain and its meninges determined by age and the integrity of the lymphatic pathways of brain drainage and clearance

    Adushkina Viktoria; Zlatogorskaya Daria; Shirokov Alexander et al.

    Journal of Innovative Optical Health Sciences, Vol. 19 No. 05 · 2026 · English · DOAJ Scopus

    Photobiomodulation (PBM) is a promising therapeutic intervention for age-related neurodegenerative diseases. It has recently been discovered that the meningeal lymphatic vessels (MLVs) are targets for PBM, which mediates a PBM-related increase in brain drainage and clearance. However, with age, the…

  15. Journal Article

    Revealing of imaging photoplethysmography changes in cerebral blood supply caused by temporary arterial occlusion

    Alexey Y. Sokolov; Valeriy V. Zaytsev; Anton V. Shcherbinin et al.

    Journal of Innovative Optical Health Sciences, Vol. 19 No. 05 · 2026 · English · DOAJ Scopus

    During temporary arterial occlusion (TAO), which is often used in neurosurgery, particularly when clipping aneurysms, it is critically important to intraoperatively assess changes in blood supply to the brain. This study aimed to demonstrate the feasibility of using imaging photoplethysmography…

  16. Journal Article

    Diabetes mellitus progression exacerbates post-stroke damage and diminishes the efficacy of urokinase

    Shaojun Liu; Jiawei Huang; Tingting Yu et al.

    Journal of Innovative Optical Health Sciences, Vol. 19 No. 05 · 2026 · English · DOAJ Scopus

    Stroke is a leading cause of global mortality, and diabetes mellitus (DM) is an independent risk factor for ischemic stroke. Although longer DM duration is associated with increased stroke risk, how disease progression influences post-stroke pathology and thrombolytic efficacy remains poorly…

  17. Journal Article

    Tissue-selective contrast enhancement in cervical imaging using hemoglobin mapping informed by optical modeling

    Tien Tran Van; Cat Phan Ngoc Khuong

    Journal of Innovative Optical Health Sciences, Vol. 19 No. 05 · 2026 · English · DOAJ Scopus

    White-light imaging (WLI)-based cervical colposcopy is often limited by strong surface reflections, low tissue contrast, and unstable color appearance, making blood vessels and bleeding regions difficult to visualize. Existing image enhancement techniques largely rely on global processing and lack…

  18. Journal Article

    Pathological investigation on healthy ovarian tissue sections by an integrated label-free multimodality optical microscopy

    Haorui An; Xiangtao Kong; Qidong Liu et al.

    Journal of Innovative Optical Health Sciences, Vol. 19 No. 05 · 2026 · English · DOAJ Scopus

    Nonlinear multimodal imaging integrates nonlinear optical techniques with multimodal imaging approaches, providing a powerful research tool for investigating the tumor microenvironment and pathological mechanisms of malignancy through its label-free operation and high-resolution capabilities. We…

  19. Journal Article

    Comparative analysis and classification of elemental composition in folic acid using laser-induced breakdown spectroscopy coupled with machine learning

    Bushra Fayyaz; Adil Shahbaz; Yue Tang et al.

    Journal of Innovative Optical Health Sciences, Vol. 19 No. 05 · 2026 · English · DOAJ Scopus

    Folic acid (FA) tablets are widely used by pregnant women during the first few weeks of pregnancy. The qualitative analysis and classification of FA tablets from different companies of China and Pakistan are reported through a comparative laser-induced breakdown spectroscopy (LIBS) machine-learning…

  20. Journal Article

    Non-invasive hemoglobin assessment via RGB-imaging: The impact of physiology and interpatient variability on the method accuracy

    Georgy Denisenko; Oleg Khvan; Ilia Bardadin et al.

    Journal of Innovative Optical Health Sciences, Vol. 19 No. 05 · 2026 · English · DOAJ Scopus

    Accurate and rapid assessment of hemoglobin (Hb) concentration is essential for medical decision-making in preoperative evaluations, anemia screening, and blood loss monitoring. RGB imaging, which estimates Hb levels by analyzing tissue color in regions such as nail beds, has attracted growing…