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Clinics

Scopus

ISSN 1807-5932 · Elsevier España · 3.191 artikel di indeks

  1. Artikel Jurnal Teks lengkap

    Clinical features of hereditary angioedema and warning signs (H4AE) for its identification

    Pedro Giavina-Bianchi; Marcelo Vivolo Aun; Juliana Fóes Bianchini Garcia dkk.

    Clinics, Vol. 77 · 2022 · Inggris · DOAJ Scopus

    Abstract Objectives The study describes a case series of hereditary angioedema with C1 Inhibitor Deficiency (C1INH-HAE) in order to corroborate six clinical warning signs “HAAAAE (H4AE)” to enable early identification of this disease. Methods The authors analyzed the C1INH-HAE cohort to analyze the…

  2. Artikel Jurnal Teks lengkap

    Gathering patients and rheumatologists' perceptions to improve outcomes in idiopathic inflammatory myopathies

    Isabela M. Bertoglio; Glaucia F. Abrahao; Fernando H.C. de Souza dkk.

    Clinics, Vol. 77 · 2022 · Inggris · DOAJ Scopus

    Abstract Objective Therapeutic targets in Idiopathic Inflammatory Myopathies (IIM) are based on the opinions of physicians/specialists, which may not reflect the main concerns of patients. The authors, therefore, assessed the outcome concerns of patients with IIM and compared them with the concerns…

  3. Artikel Jurnal Teks lengkap

    MicroRNA-128b mediates lipopolysaccharide-induced apoptosis via reactive oxygen species in human pulmonary microvascular endothelial cells

    Guangwen Long; Xiulin Yang; Chunling Ji dkk.

    Clinics, Vol. 77 · 2022 · Inggris · DOAJ Scopus

    ABSTRACT Objectives: This study aimed to explore the effects of miR-128b in the regulation of Lipopolysaccharide (LPS) induced apoptosis. Methods: Human Pulmonary Microvascular Endothelial Cells (HPMECs) were transfected with an miR-128b inhibitor and stimulated with LPS for 24 h. FCM was performed…

  4. Artikel Jurnal Teks lengkap

    Arterial stiffness and atrial fibrillation: A review

    Joao Gabriel Batista Lage; Alexandre Lemos Bortolotto; Mauricio Ibrahim Scanavacca dkk.

    Clinics, Vol. 77 · 2022 · Inggris · DOAJ Scopus

    ABSTRACT Arterial stiffness has been investigated as part of the physiopathology of arterial hypertension since the 1970s. Its role in increasing the “pulsatile load” imposed over the Left Ventricle (LV) has been intensely studied recently and has helped in understanding the mechanisms of Atrial…

  5. Artikel Jurnal Teks lengkap

    Ischemic stroke in 455 COVID-19 patients

    Josef Finsterer; Fulvio Alexandre Scorza; Carla Alessandra Scorza dkk.

    Clinics, Vol. 77 · 2022 · Inggris · DOAJ Scopus

    ABSTRACT There is increasing evidence that COVID-19 can be associated with ischemic stroke (COVID-stroke). The frequency and pathogenesis of COVID-stroke, however, remains largely unknown. This narrative review aimed at summarizing and discussing current knowledge about frequency and pathogenesis…

  6. Artikel Jurnal Teks lengkap

    Plasma lathosterol measures rates of cholesterol synthesis and efficiency of dietary phytosterols in reducing the plasma cholesterol concentration

    Valéria Sutti Nunes; Angela de Oliveira Godoy Ilha; Guilherme da Silva Ferreira dkk.

    Clinics, Vol. 77 · 2022 · Inggris · DOAJ Scopus

    Abstract Objectives Because the plasma campesterol/cholesterol ratio does not differ between groups that absorb different amounts of cholesterol, the authors investigated whether the plasma Phytosterols (PS) relate to the body's cholesterol synthesis rate measured as non-cholesterol sterol…

  7. Artikel Jurnal Teks lengkap

    IRF4 suppresses osteogenic differentiation of BM-MSCs by transcriptionally activating miR-636/DOCK9 axis

    Xuepu Zhang; Yue Zhang; Limin Yang dkk.

    Clinics, Vol. 77 · 2022 · Inggris · DOAJ Scopus

    Abstract Objectives Osteoblasts are derived from Bone Marrow-derived Mesenchymal Stem Cells (BM-MSCs), which play an indispensable role in bone formation. In this study, the authors aim to investigate the role of IRF4 in the osteogenic differentiation of BM-MSCs and its potential molecular…

  8. Artikel Jurnal Teks lengkap

    microRNA-181a-5p impedes the proliferation, migration, and invasion of retinoblastoma cells by targeting the NRAS proto-oncogene

    Ming Ouyang; Guiqin Liu; Cheng Xiong dkk.

    Clinics, Vol. 77 · 2022 · Inggris · DOAJ Scopus

    Abstract Objectives Accumulating research have reported that microRNAs (miRNAs) play important roles in Retinoblastoma (RB). Nonetheless, the function and underlying mechanism of miR-181a-5p in RB remain ambiguous. Methods The relative expression levels of miR-181a-5p and NRAS mRNA were detected by…

  9. Artikel Jurnal Teks lengkap

    Influence of invertor and evertor muscle fatigue on functional jump tests and postural control: A prospective cross-sectional study

    Gabriela Borin Castillo; Guilherme Carlos Brech; Nátalia Mariana Silva Luna dkk.

    Clinics, Vol. 77 · 2022 · Inggris · DOAJ Scopus

    ABSTRACT Objective: Fatigue of the ankle’s stabilizing muscles may influence the performance of functional activities and postural control. The purpose of this study was to evaluate the performance of healthy young adults using functional jump tests and static posturography control under pre- and…

  10. Artikel Jurnal Teks lengkap

    Clinical value of preferred endoscopic ultrasound-guided antegrade surgery in the treatment of extrahepatic bile duct malignant obstruction

    Xuan Zhao; Lihong Shi; Jinchen Wang dkk.

    Clinics, Vol. 77 · 2022 · Inggris · DOAJ Scopus

    ABSTRACT Objectives: To explore the clinical value of preferred ultrasound endoscopic guided biliary drainage in patients with extrahepatic biliary obstruction with intrahepatic biliary ectasis. Methods: A total of 58 patients with malignant obstruction and intrahepatic bile duct expansion…

  11. Artikel Jurnal Teks lengkap

    Increasing rate of anti-SARS-CoV-2 antibodies between the first and second waves of COVID-19 in Sao Paulo, Brazil: A cross-sectional blood donors-based study

    Nayara Moya Rios do Vale; Flavia Roche Moreira Latini; Carine Prisco Arnoni dkk.

    Clinics, Vol. 77 · 2022 · Inggris · DOAJ Scopus

    ABSTRACT Background: SARS-CoV-2 infections rapidly spread along with Brazilian territory with heterogeneous transmission and mortality rates, mostly depending on region and period. Investigation of SARS-CoV-2 antibodies is an important tool to understand virus circulation. Given that blood donors…

  12. Artikel Jurnal Teks lengkap

    Circ_0075825 promotes gastric cancer progression via adsorbing miR-432-5p to modulate SOX9

    He Li; Xiaohua Zhou; Zhuangming Yu dkk.

    Clinics, Vol. 77 · 2022 · Inggris · DOAJ Scopus

    Abstract Methods Circ_0075825 expression in adjacent tissues and GC tissues was evaluated by bioinformatics method and quantitative Reverse Transcription Polymerase Chain Reaction (qRT-PCR). How circ_0075825 regulated GC cell growth, migration, invasion, and apoptosis were investigated by cell…

  13. Artikel Jurnal Teks lengkap

    Magnetic resonance imaging and previous cesarean section in placenta accrete spectrum disorder: Predictor model

    Rodrigo Pamplona Polizio; Fernando Ide Yamauchi; Renata Franco Pimentel Mendes dkk.

    Clinics, Vol. 77 · 2022 · Inggris · DOAJ Scopus

    Abstract Objective To evaluate objective criteria of Magnetic Resonance Imaging (MRI) of Placenta Accreta Spectrum disorder (PAS) analyzing interobserver agreement and to derive a model including imaging and clinical variables to predict PAS. Methods A retrospective review including patients…

  14. Artikel Jurnal Teks lengkap

    Chronic inflammatory diseases, subclinical atherosclerosis, and cardiovascular diseases: Design, objectives, and baseline characteristics of a prospective case-cohort study ‒ ELSA-Brasil

    Isabela M. Bensenor; Alessandra C. Goulart; Alexandre C. Pereira dkk.

    Clinics, Vol. 77 · 2022 · Inggris · DOAJ Scopus

    Abstract Objectives This analysis describes the protocol of a study with a case-cohort to design to prospectively evaluate the incidence of subclinical atherosclerosis and Cardiovascular Disease (CVD) in Chronic Inflammatory Disease (CID) participants compared to non-diseased ones. Methods A…

  15. Artikel Jurnal Teks lengkap

    Effects of ganglioside GM1 and erythropoietin on spinal cord injury in mice: Functional and immunohistochemical assessments

    Alessandro Gonzalez Torelli; Alexandre Fogaça Cristante; Tarcísio Eloy Pessoa de Barros-Filho dkk.

    Clinics, Vol. 77 · 2022 · Inggris · DOAJ Scopus

    ABSTRACT Objectives: To evaluate the functional and immunohistochemical effects of ganglioside GM1 and erythropoietin following experimental spinal cord injury. Methods: Thirty-two male BALB/c mice were subjected to experimental spinal cord injury using the NYU Impactor device and were randomly…

  16. Artikel Jurnal Teks lengkap

    Risk of osteoporotic fracture in women using the FRAX tool with and without bone mineral density score in patients followed at a tertiary outpatient clinic ‒ An observational study

    Maria Helena Sampaio Favarato; Maria Flora de Almeida; Arnaldo Lichtenstein dkk.

    Clinics, Vol. 77 · 2022 · Inggris · DOAJ Scopus

    ABSTRACT Objectives: Fragility fractures increase morbidity and mortality. Adding assessment of clinical risk factors independently or as a previous step to Bone Densitometry (BD) should provide better accuracy in fracture risk prediction. FRAX tool might be used to stratify patients in order to…

  17. Artikel Jurnal Teks lengkap

    Lacticaseibacillus rhamnosus modulates the inflammatory response and the subsequent lung damage in a murine model of acute lung inflammation

    Fabiana Olimpio; Jose Roberto Mateus da Silva; Rodolfo P. Vieira dkk.

    Clinics, Vol. 77 · 2022 · Inggris · DOAJ Scopus

    ABSTRACT Objective: The present study investigated the anti-inflammatory effect of the probiotic Lacticaseibacillus rhamnosus (Lr) on lung inflammation induced by Lipopolysaccharide (LPS) of Escherichia coli in C57BL/6 mice. Methods: C57BL/6 mice were divided into four groups: control, LPS, Lr (1…

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