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Rare Tumors
Scopus
ISSN 2036-3605 · SAGE Publishing · 650 artikel di indeks
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Artikel Jurnal
Sensitivity and specificity of FDG-PET in detecting abdominopelvic disease in desmoplastic small round cell tumor
Purpose Desmoplastic Small Round Cell Tumor (DSRCT), a rare sarcoma, is characterized by disseminated peritoneal disease often with innumerable implants which are difficult to image. Patients are typically treated with neoadjuvant chemotherapy followed by attempted gross total resection. FDG-PET…
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Artikel Jurnal
Genomic landscape of schwannomas: An analysis of somatic mutations and demographic disparities
Schwannomas are typically benign nerve sheath tumors characterized by mutations in the NF2 gene. However, the complete genomic landscape, especially across diverse patient populations, remains incompletely understood. This study aims to provide a comprehensive analysis of the somatic mutations in…
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Artikel Jurnal
Postoperative adjuvant eribulin in high-risk patients with soft tissue sarcoma: A retrospective study of eight cases
Background The role of perioperative chemotherapy in localized soft tissue sarcomas (STS) remains controversial, particularly in older adult patients and those with considerable comorbidities who may not tolerate anthracycline-based regimens. Although eribulin has demonstrated efficacy and safety…
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Artikel Jurnal
Extragastrointestinal stromal tumor involving the adrenal region: A rare case report
Adrenal masses are increasingly detected due to advanced imaging modalities, yet their differential diagnoses remain broad and challenging. Extragastrointestinal stromal tumors (EGISTs) are rare mesenchymal tumors sharing histologic and immunophenotypic features with GISTs but occurring outside the…
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Artikel Jurnal
Bilateral breast metastatic rectal cancer with MET gene amplification: A rare case report
Breast metastases originating from colorectal cancer are extremely rare, accounting for
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Artikel Jurnal
Pulmonary carcinoid harboring a G12C mutation identified through comprehensive genomic profiling and responding to sotorasib: A case report
Pulmonary carcinoids are the pulmonary counterparts of gastrointestinal neuroendocrine tumors (NETs) G1-2. They may cause distant metastasis, leading to a poor prognosis, and requiring chemotherapy. Reports on cases harboring driver gene mutations remain limited. A man in his late 60s visited to JA…
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Artikel Jurnal
Spindle cell (sarcomatoid) squamous cell carcinoma of the esophagus: A case report and a review of the literature
Esophageal squamous cell carcinoma (SCC) is a significant global health issue, and spindle cell squamous cell carcinoma (SpCC) is a rare variant accounting for up to 2% of cases. SpCC is characterized by a biphasic histological pattern comprising both carcinomatous and sarcomatous components…
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Artikel Jurnal
Prognostic significance of systemic inflammatory indices in squamous cell carcinoma of the anal canal: A retrospective cohort study
Background Squamous cell carcinoma of the anal canal is a rare gastrointestinal malignancy with heterogeneous outcomes despite standardized chemoradiotherapy. Systemic inflammation has been implicated in tumor progression, and hematological indices such as the neutrophil-to-lymphocyte ratio (NLR)…
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Artikel Jurnal
Primary hepatic leiomyosarcoma diagnosed after right hepatectomy: A rare case report
This is a case report of primary hepatic leiomyosarcoma. An 82-year-old Japanese man presented with fever and mild abdominal pain. Laboratory testing demonstrated marked inflammation and substantial elevations of CA19-9 and PIVKA-II. Computed tomography revealed a large necrotic mass in the right…
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Artikel Jurnal
Chondromyxoid fibroma in a 24-year-old female: A case report highlighting its rarity, diagnostic challenges, and importance of surgical management
Chondromyxoid fibroma (CMF) is an uncommon benign bone tumor, involving less than 1% of all bone neoplasms and is slightly more predominant in males. This case report describes a 24-year-old female patient who presented with a painless, progressively enlarging swelling on the left upper leg for six…
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Artikel Jurnal
Urine 5-HIAA and quality of life in neuroendocrine neoplasia. Is there an association?
Background To determine whether urine 5-HIAA (u5HIAA) concentrations correlate with health-related quality of life (HRQL) in patients with neuroendocrine neoplasms (NEN). Methods A retrospective single-centre cross-sectional study was conducted including 386 patients with histological or…
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Artikel Jurnal
Vulvar Leiomyoma in a young woman: A case report of a rare benign soft tissue tumor from Woldia, Ethiopia
Vulvar Leiomyoma is an extremely rare benign tumor of smooth muscle origin, accounting for a small fraction of Vulvar neoplasms. It often mimics Bartholin’s cyst or other soft tissue masses, posing diagnostic challenges. We present a case of a 19-year-old unmarried woman with a Vulvar mass…
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Artikel Jurnal
T-cell lymphoma of the breast and ovary presenting as a second malignant neoplasm in a pediatric leukemia survivor: A case report and literature review
Second malignant neoplasms (SMNs) are rare but serious late effects in childhood acute lymphoblastic leukemia (ALL) survivors. Mature peripheral T-cell lymphomas involving both the breast and ovary are exceedingly rare, and their relationship with germline predisposition variants remains poorly…
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Artikel Jurnal
A case of respiratory epithelial adenomatoid hamartoma in a patient suffering from non-steroidal anti-inflammatory drug - exacerbated respiratory disease
Respiratory epithelial adenomatoid hamartoma (REAH) is a rare lesion located mostly in the anterior and upper parts of the nasal cavity, caused by pseudo-glandular proliferation of the respiratory epithelium, enriched with goblet cells. The stroma is characterized by a dense infiltrate composed…
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Artikel Jurnal
Long-term disease stabilization with lenvatinib in advanced thymic carcinoma: A case report
Lenvatinib, a multi-kinase inhibitor, has shown promising activity in unresectable thymic carcinoma, but long-term real-world data are scarce. We describe a 72-year-old woman with Masaoka stage IVb thymic squamous cell carcinoma who experienced disease progression after ADOC chemotherapy and…
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Artikel Jurnal
Palatal malignant peripheral nerve sheath tumor: A case report and review of literature
Malignant peripheral nerve sheath tumor (MPNST) is a rare, aggressive soft tissue malignancy associated with neurofibromatosis type 1. Although MPNST most commonly occurs in the extremities and trunk, it is rare in the head and neck region and extremely rare in the oral cavity, including the…
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Artikel Jurnal
Diagnostic utility of Ki-67 proliferation index, PSA, and other immunohistochemical markers in prostatic basal cell carcinoma: A review of 24 cases in the current literature and discussion on current treatment and diagnostics
Background Basal cell carcinoma (BCC) of the prostate is a rare and poorly characterized malignancy distinct from conventional prostatic adenocarcinoma. Due to its rarity, diagnostic challenges arise, often leading to misclassification and delayed management. Immunohistochemical markers such as…
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Artikel Jurnal
Durable remission of metastatic myxoid liposarcoma following the cautious addition of pembrolizumab to ongoing pazopanib treatment: A case report
Responses to conventional treatments, like chemotherapy and targeted agents, are generally infrequent, and of brief duration in patients with metastatic soft tissue sarcomas. We present a case of metastatic myxoid liposarcoma that achieved biopsy-proven complete remission with minimal toxicity…
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Artikel Jurnal
Chronic myeloid leukemia presenting with isolated central nervous system lymphoid blast crisis: A case report
Background Chronic myeloid leukemia (CML) is a myeloproliferative neoplasm driven by the Philadelphia chromosome, typically progressing through chronic, accelerated, and blast phases. Blast crisis may be myeloid or lymphoid. Isolated central nervous system (CNS) involvement is rare and represents a…
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Artikel Jurnal
A rare case of bilateral adnexal Müllerian adenosarcoma arising from endometriosis: A case report and literature review
Background Müllerian adenosarcoma is an uncommon mixed epithelial–mesenchymal neoplasm that predominantly develops in the uterine corpus and rarely occurs in extrauterine sites, including the ovary. Ovarian adenosarcoma is associated with a more aggressive course and is often linked to…