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Neural Plasticity
Scopus
ISSN 2090-5904 · Wiley · 2,102 articles in the index
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Journal Article
Berberine Alleviates Lipopolysaccharide-Induced Impairments in Neuroplasticity and Spatial Memory by Modulating Microglial Polarization via MAPK Signaling Inhibition
Neuroinflammation-induced cognitive impairment is characterized by a continued decline in memory, executive functioning, and information-processing abilities. Although berberine (BBR) exhibits anti-inflammatory and neuroprotective properties, its ability to mitigate cognitive deficits by regulating…
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Journal Article
Differential Impacts of Fronto-Cerebellar tACS and tVNS on Motor Learning: Evidence for Sex-Related Neural Modulation
Noninvasive brain stimulation (NIBS) techniques rely on distinct mechanisms and engage different neural circuits. For instance, transcranial alternating current stimulation (tACS) targets cortical networks directly, while transcutaneous vagus nerve stimulation (tVNS) influences the brain via…
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Journal Article
Investigating the Role of Sodium Butyrate in Mouse Models of IBD: A Multimodal Structural and Functional MRI Study
Patients with inflammatory bowel disease (IBD) experience abnormalities in the central nervous system via the gut–brain axis (GBA), leading to changes in brain structure and function. Butyrate has been shown to influence the central nervous system via the GBA, with potential benefits for…
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Journal Article
Mechanosensitive Ion Channels and Neuroplasticity in Tuina Therapy: Molecular Mechanisms and Therapeutic Implications
Tuina is a traditional Chinese manual therapy distinguished from generic massage by its acupoint- and meridian-based manipulations, and it is commonly used in the management of neurological and musculoskeletal disorders, although its underlying biological mechanisms remain incompletely defined…
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Journal Article
Consistent Brain Entropy Changes During Rumination Across Three Magnetic Resonance Imaging Scanners
Rumination, characterized by repetitive and self-referential thinking, is closely linked to depression and a broad range of psychiatric disorders. However, previous research has predominantly relied on task activation or network-level approaches, leaving critical gaps in our understanding of local…
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Journal Article
Ginsenoside Rg1 Improves PTSD-Like Sleep Disturbances in Male Mice: Involvement of NLRP3-Related Inflammatory and Apoptotic Pathways
Sleep disturbances (SD) are not merely symptoms of posttraumatic stress disorder (PTSD), but also amplify and perpetuate all other PTSD phenotypes. Ginsenoside Rg1 is extensively applied in managing neuropsychiatric diseases. Nevertheless, its impact on PTSD-like SD and mechanisms remain largely…
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Journal Article
Resting-State Coactivation Patterns of Language Reorganization in Brain Tumors
We investigated the temporal dynamics of resting-state brain activity associated with language reorganization in patients with left-hemisphere brain tumors using coactivation pattern (CAP) analysis of functional MRI. This retrospective study included 106 right-handed patients who underwent both…
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Journal Article
Selective Synaptic Remodeling in Rat Auditory and Visual Cortices Following Noise-Induced Permanent Hearing Loss in Adulthood
In adults with acquired hearing loss, cortical reorganization and cross-modal plasticity critically influence the timing and outcomes of cochlear implantation. This study examined the effects of 2 weeks of bilateral auditory deprivation—induced by intense broadband noise—on the structure and gene…
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Journal Article
Environmental Enrichment Enhances Visual Function in Adult Amblyopia: Association With miR-132/HDAC3 Regulation
Amblyopia is a neurodevelopmental disorder for which effective treatments in adults are limited due to reduced cortical plasticity. Environmental enrichment (EE) can partially restore this plasticity, but the underlying molecular mechanisms remain unclear. This study investigated whether the…
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