13 hasil
Menampilkan 1–13 · 0,32 detik · RSS
-
Artikel Jurnal
Neoadjuvant Nivolumab plus Chemotherapy in Resectable Lung Cancer
BACKGROUND: Neoadjuvant or adjuvant chemotherapy confers a modest benefit over surgery alone for resectable non-small-cell lung cancer (NSCLC). In early-phase trials, nivolumab-based neoadjuvant regimens have shown promising clinical activity; however, data from phase 3 trials are needed to confirm…
-
Artikel Jurnal Teks lengkap
Interphase in Polymer Nanocomposites
The lightweight and high-strength functional nanocomposites are important in many practical applications. Natural biomaterials with excellent mechanical properties provide inspiration for improving the performance of composite materials. Previous studies have usually focused on the bionic design of…
-
Artikel Jurnal Teks lengkap
Luminescent First-Row Transition Metal Complexes
Precious and rare elements have traditionally dominated inorganic photophysics and photochemistry, but now we are witnessing a paradigm shift toward cheaper and more abundant metals. Even though emissive complexes based on selected first-row transition metals have long been known, recent conceptual…
-
Artikel Jurnal
The ménage à trois of autophagy, lipid droplets and liver disease
Autophagic pathways cross with lipid homeostasis and thus provide energy and essential building blocks that are indispensable for liver functions. Energy deficiencies are compensated by breaking down lipid droplets (LDs), intracellular organelles that store neutral lipids, in part by a selective…
-
Artikel Jurnal Teks lengkap
How autophagy controls the intestinal epithelial barrier
Macroautophagy/autophagy is a cellular catabolic process that results in lysosome-mediated recycling of organelles and protein aggregates, as well as the destruction of intracellular pathogens. Its role in the maintenance of the intestinal epithelium is of particular interest, as several…
-
Artikel Jurnal Teks lengkap
A snapshot of the PD-1/PD-L1 pathway
Cancer cells can evade the attack from host immune systems via hijacking the regulatory circuits mediated by immune checkpoints. Therefore, reactivating the antitumor immunity by blockade of immune checkpoints is considered as a promising strategy to treat cancer. Programmed death protein 1 (PD-1)…
-
Artikel Jurnal Teks lengkap
Mitochondrial DNA stress triggers autophagy-dependent ferroptotic death
Pancreatic cancer tends to be highly resistant to current therapy and remains one of the great challenges in biomedicine with very low 5-year survival rates. Here, we report that zalcitabine, an antiviral drug for human immunodeficiency virus infection, can suppress the growth of primary and…
-
Artikel Jurnal Teks lengkap
A Tutorial on Conducting and Interpreting a Bayesian ANOVA in JASP
L’analyse de variance (ANOVA) est la procédure standard utilisée pour l’inférence statistique dans les plans factoriels. En règle générale, les analyses de variance sont exécutées à l’aide de statistiques fréquentistes, où les valeurs p déterminent la significativité statistique en termes de « tout…
-
Artikel Jurnal
Linguistique générale et linguistique française
A biblioteca dixital de Galicia forma parte de Galiciana. Naceu co obxectivo de difundir e preservar o rico acervo bibliográfico e patrimonial galego. O proxecto pretende non só a dixitalización dos fondos patrimoniais senón tamén a normalización do acceso mediante a aplicación das últimas…
-
Artikel Jurnal Teks lengkap
Les professionnels de santé face à la pandémie de la maladie à coronavirus (COVID-19) : quels risques pour leur santé mentale ?
OBJECTIVES: The coronavirus disease 2019 (COVID-19) pandemic has caused major sanitary crisis worldwide. Half of the world has been placed in quarantine. In France, this large-scale health crisis urgently triggered the restructuring and reorganization of health service delivery to support emergency…
-
Artikel Jurnal Teks lengkap
C-reactive protein levels in the early stage of COVID-19
BACKGROUND: COVID-19 is a new infectious disease, for which there is currently no treatment. It is therefore necessary to explore biomarkers to determine the extent of lung lesions and disease severity. OBJECTIVE: We aimed to assess the usefulness of CRP levels in the early stage of COVID-19 and to…
-
Artikel Jurnal Teks lengkap
Assurer les soins aux patients souffrant de troubles psychiques en France pendant l’épidémie à SARS-CoV-2