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Artikel Jurnal Teks lengkap
Isolation and genomic analysis of secondary metabolism in cave Actinomycetota from biofilms and Ceuthophilus
We report the isolation and genomic sequencing of nine Actinomycetota obtained from both cave biofilms and trogloxenic Ceuthophilus (cave crickets). Strains were isolated from samples via actinomycetota-selective media and sequenced using nanopore sequencing. Provisional taxonomic inference of…
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Structural Basis for how Sialoglycan-binding Viridans Streptococci Accommodate Ligands that Exceed the Characterized Binding Site
During endocardial infections, viridans group streptococci use proteins containing siglec-like binding regions to engage sialic acid-capped O- GalNAc glycans on platelet glycoprotein GPIbα. Much past work used isolated di-, tri-, or tetrasaccharide partial ligands to interrogate this sialoglycan…
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Artikel Jurnal Teks lengkap
Isolation, characterization, and annotation of two bacteriophage from North Carolina soil using Arthrobacter globiformis : HamCheese and Kihatsu
Bacteriophage HamCheese and Kihatsu are siphoviruses isolated from soil in Raleigh, NC and Clayton, NC, respectively, using Arthrobacter globiformis , B2979. HamCheese is assigned to actinobacteriophage cluster AS based on gene content similarity. Its 38454 base pair genome encodes 67 putative…
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Artikel Jurnal Teks lengkap
‘Cough and sneeze into your elbow’: a field study testing the effects of persuasive messages on compliance with behavioral measures to prevent the spread of respiratory viruses
BACKGROUND: Effective persuasive messages can contribute to enhancing pandemic preparedness and public health. An essential requirement for this is an excellent understanding of the effects of exposure to persuasive messages on compliance with behavioral measures against the spread of respiratory…
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Artikel Jurnal Teks lengkap
Developing a theory and evidence-based intervention for black African women using the COM-B model and behaviour change wheel: BALANCED programme
BACKGROUND: Obesity is a major global health issue, increasing morbidity and mortality through its association with non communicable diseases. Black African women experience disproportionately high obesity rates, reaching 37 percent in the UK. They face cultural, social, and systemic barriers to…
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Artikel Jurnal Teks lengkap
Can we escape from top-priority ESKAPE pathogens?
The ESKAPE pathogens – Enterococcus faecium, Staphylococcus aureus, Klebsiella pneumoniae, Acinetobacter baumannii, Pseudomonas aeruginosa, and Enterobacter spp. – are designated by the World Health Organization as critical-priority multidrug-resistant organisms. These bacteria are leading…
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Artikel Jurnal Teks lengkap
Whey protein intakes up to 0.4g/kg body mass are well tolerated before a 10km run at 85% of race pace: a clinical trial
BACKGROUND: Exercise induced gastrointestinal (GI) symptoms affect a significant portion of endurance runners, resulting in discomfort and suboptimal performance. Protein intakes pre-exercise may have benefits; however, research investigating dietary intake prior to exercise suggests that many…
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Artikel Jurnal Teks lengkap
Choosing real-world data for clinical and epidemiological research: methodological lessons from NHIRD and TriNetX—A narrative review
INTRODUCTION: Large-scale real-world data (RWD) are increasingly used in clinical and epidemiological research, although database-specific structures and limitations may affect study validity and applicability. The Taiwan National Health Insurance Research Database (NHIRD) and the TriNetX network…
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Artikel Jurnal Teks lengkap
Response to letter regarding ‘bidirectional association of daily steps with sarcopenia: a longitudinal study’
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Artikel Jurnal Teks lengkap
Virtual reality and perioperative anxiety: a randomized controlled trial
Preoperative anxiety is a feeling of insecurity, physical and psychological discomfort that arises from the prospect of undergoing surgery. Managing anxiety is a therapeutic cornerstone in anesthetic care. Virtual reality has shown a significant effect on managing anxiety and pain by leveraging the…
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Artikel Jurnal Teks lengkap
Long-term mortality in pediatric sepsis: a systematic review and meta-analysis
BACKGROUND: Pediatric sepsis represents a significant factor in the mortality rates among children, with survivors remaining highly fragile during the period following discharge. While in-hospital and short-term mortality have been widely studied, the long-term mortality of pediatric sepsis is not…
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Artikel Jurnal Teks lengkap
Economic implications of the different statin prescribing patterns in Central Portugal: a longitudinal analysis
BACKGROUND: Statins are one of the most widely used therapeutic classes and have significantly contributed to health care expenditures with reported variability between countries and regions. We aim to identify the economic implications of different statin prescription patterns in the central…
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Artikel Jurnal Teks lengkap
Congenital babesiosis in China: first molecularly confirmed case of vertical transmission of Babesia microti
Congenital babesiosis is rarely reported globally. We report a 74-day-old male infant presented with fever, pallor, and severe, life-threatening haemolytic anaemia (haemoglobin: 45 g/L). The infant had 16% parasitemia with ring forms evident on peripheral blood smear. Babesia microti infection was…
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Artikel Jurnal Teks lengkap
Current research hotspots and difficulties of chronic prostatitis/chronic pelvic pain syndrome: neuroendocrine mechanism
BACKGROUND: Chronic prostatitis/chronic pelvic pain syndrome (CP/CPPS) presents a significant clinical challenge in urology. Traditional pathophysiological models emphasize infection and local inflammation; however, the limited efficacy of conventional therapies suggests the involvement of deeper…
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Artikel Jurnal Teks lengkap
Mortality prediction in hemodialysis patients using heart rate variability and skin sympathetic nerve activity
Patients undergoing maintenance hemodialysis (HD) face a substantially elevated risk of all-cause mortality, yet robust tools for individualized risk stratification remain limited. This multicenter study developed a predictive model integrating dynamic autonomic nervous system (ANS) markers – heart…
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Artikel Jurnal Teks lengkap
‘We can go hand in hand’ – patients with COPD and their experiences of relational continuity of care in Swedish primary care: a qualitative study
AIM: This study aimed to explore how patients with chronic obstructive pulmonary disease (COPD) experience continuity of care through their encounters with a specialised asthma/COPD Registered Nurse in primary care. DESIGN: An inductive qualitative study using interpretive description. METHODS…
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Artikel Jurnal Teks lengkap
The colloidal stability of albumin-based drug delivery systems has a profound effect on tumoricidal activity
Human serum albumin (HSA) has attracted significant attention in drug delivery since the approval of Abraxane in 2005. Abraxane is a nanoparticle albumin-bound paclitaxel (nab-PTX) formulation. Although HSA offers advantages such as prolonged circulation time (half-life ~19 days) and intrinsic…
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Artikel Jurnal Teks lengkap
Acid-sensing ion channel 1a contributes to the calcium/calmodulin-dependent ferroptosis and aggravates intervertebral disc degeneration
OBJECTIVES: Acid-sensing ion channel 1a (ASIC1a) functions as an extracellular acid sensor, with its activation frequently associated with age-related diseases. We aim to investigate the expression pattern of ASIC1a in the ferroptosis of degenerated nucleus pulposus (NP) tissues and NP cells…
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Artikel Jurnal Teks lengkap
Functional brain alterations in anxious depression: Insights from whole-brain fMRI and meta-analysis
OBJECTIVE: The aim of our study was to investigate neurobiological markers and gender difference for diagnosing anxious major depressive disorder (aMDD) through a meta-analysis. METHODS: We systematically searched multiple databases for whole-brain neuroimaging studies comparing anxious major…
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Artikel Jurnal Teks lengkap
Post-mortem surveillance: an innovative strategy to detect and prevent spread of Nipah virus infection in humans
Nipah virus (NiV) remains a persistent public-health threat in Bangladesh. The national sentinel surveillance system has operated since 2006, yet fatal infections that occur before assessment often go untested. We piloted a post-mortem surveillance component at three sentinel hospitals (December…
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