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Artikel Jurnal Teks lengkap
Lying Down Nystagmus in Lateral Canal Paroxysmal Positional Vertigo
Introduction: The aim of this study was to determine the position of otoconial debris in lateral ampullar or non-ampullar canalolithiasis, based on two parameters: (1) the direction of the nystagmus appearing when the patient lies down, if present, and (2) the positional nystagmus evoked by the…
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Updates on Antibody Drug Conjugates and Bispecific T-Cell Engagers in SCLC
Background/Objectives: Small-cell lung cancer (SCLC) is an aggressive neuroendocrine malignancy characterized by rapid proliferation, early metastasis, and near-universal relapse after initial therapy. While chemo-immunotherapy modestly improves first-line outcomes, survival after progression…
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The Diagnostic Potential of Eye Tracking to Detect Autism Spectrum Disorder in Children: A Systematic Review
Background: Autism spectrum disorder (ASD) is associated with distinct visual attention patterns that provide insight into underlying social-cognitive mechanisms. Methods: This systematic review (PROSPERO: CRD42023429316), conducted per PRISMA guidelines, synthesizes evidence from 14 peer-reviewed…
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Severity Scores in SARS-CoV-2 Infection—A Comprehensive Bibliometric Review and Visualization Analysis
Background/Objectives: Discovered in 2019, COVID-19 spread rapidly worldwide, leading from mild forms of the disease to critical forms or death, predominantly among vulnerable patients. Severity scores help clinicians in stratifying the risk of complications and death among patients diagnosed with…
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Fisetin Suppresses the Proliferative and Migratory Behavior of HeLa Cells by Modulating Aberrant Epigenetic Marks (Writers and Erasers)
Purpose: The reversible deviant in epigenomic modulations is the highlight of developing new anti-cancer drugs, necessitating the use of fisetin as an epigenetic modifier in the study. Methods: In silico and molecular studies were performed to analyze the modulatory effect of fisetin on various…
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Artikel Jurnal Teks lengkap
Spanish Readers Skip Articles Regardless of Gender and Number Agreement
Articles are among the most frequently encountered words during reading; however, it is not clear how deeply they are usually processed. This study examines whether native Spanish speakers use parafoveal article–noun agreement information to guide eye movements during reading. Using the…
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Artikel Jurnal Teks lengkap
Plantar Pressure Responses to Backpack Load in Long-Distance Hikers: A Cross-Sectional Observational Study
Background: Long-distance hiking usually requires carrying a backpack, adding external load to the lower limbs and modifying plantar loading patterns. Excessive loads may contribute to overuse injuries, but quantitative evidence to support current recommendations on backpack weight is still scarce…
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Epigenetic Alterations in Colitis-Associated Colorectal Cancer
Colitis-associated colorectal cancer (CAC) represents a distinct subtype of colorectal malignancy that arises in the setting of chronic inflammatory bowel disease (IBD). Unlike sporadic colorectal cancer, CAC develops through inflammation-driven molecular pathways, in which epigenetic alterations…
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When Tears Signal Vasculitis: Bilateral Dacryoadenitis as the Initial Manifestation of Granulomatosis with Polyangiitis—Case Report
Background and Clinical Significance: Granulomatosis with polyangiitis (GPA) is an ANCA-associated vasculitis that often affects the respiratory tract and kidneys, while ocular involvement is less common and may delay diagnosis. Bilateral dacryoadenitis as an initial manifestation is particularly…
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Artikel Jurnal Teks lengkap
Sexual Health After Neurological Disorders: A Comprehensive Umbrella Review of Treatment Evidence
Background/Objectives: Sexual dysfunction (SD) and broader sexual health problems are common after neurological disorders, yet interventional evidence is fragmented across conditions and outcomes. This umbrella review mapped and appraised systematic review-level evidence on interventions targeting…
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Artikel Jurnal Teks lengkap
Test–Retest Reliability of Balance Parameters Obtained with a Force Platform in Individuals with Chronic Obstructive Pulmonary Disease
Background: Impaired postural balance is a common feature in individuals with chronic obstructive pulmonary disease (COPD), increasing their risk of falls. This study aimed to evaluate the test–retest reliability of force platform parameters used to assess postural balance in individuals with COPD…
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Artikel Jurnal Teks lengkap
Drawing and Soccer Tactical Memorization: An Eye-Tracking Investigation of the Moderating Role of Visuospatial Abilities and Expertise
Dynamic drawing has emerged as a strategy to communicate tactical diagrams, yet its effectiveness remains uncertain and appears to depend on individual differences. This study investigated how the memorization and visual processing of tactical soccer scenes are influenced by drawing format (static…
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Cisplatin as a Xenobiotic Agent: Molecular Mechanisms of Actions and Clinical Applications in Oncology
Cisplatin, a platinum-based compound, is a cornerstone of modern chemotherapy and remains widely used against a variety of solid tumors, including testicular, ovarian, lung, bladder, and head and neck cancers. Its anticancer activity is primarily attributed to the formation of DNA crosslinks, which…
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Hypoxia Increases Cardiac Proteasomal Activity and Differentially Modulates Cullin-RING E3 Ligases in the Naked Mole-Rat Heterocephalus glaber
(1) Background: The naked mole-rat (Heterocephalus glaber) survives hypoxia–reoxygenation stresses by utilizing metabolic rate depression, achieved in part by downregulating nonessential genes and processes to conserve endogenous cellular resources and prevent buildup of toxic waste byproducts…
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Improved Sphincter Muscle Regeneration by Myoblasts from M. extensor carpi radialis in a Large Animal Model of Urinary Incontinence
Purpose: Stress urinary incontinence (SUI) is a significant medical challenge affecting substantial parts of modern societies. Several studies suggested that cell therapy may alleviate the symptoms. However, in many cases, the overall efficacy was not satisfactory for the patient’s needs. Moreover…
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Artikel Jurnal Teks lengkap
Application of Medicinal Mushrooms for the Treatment of Peripheral Nerve Injury: A Systematic Review
Background/Objective: Current treatments for peripheral nerve injury (PNI) lack robust evidence to suggest complete recovery; hence, alternative therapeutics offer new opportunities to develop more effective protocols. Mushroom species and their related components are considered potential…
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Beyond the Skin: Topical Amphotericin B Nanocarriers Targeting Cutaneous Leishmaniasis with Suppression of Lymphatic Parasite Burden
Background/Objectives: Cutaneous leishmaniasis (CL) remains a global health challenge, with treatment options often limited by drug resistance and systemic toxicity. Amphotericin B (AmB) represents a promising alternative. but intravenous administration causes severe systemic adverse effects…
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Artikel Jurnal Teks lengkap
A Systematic Review and Meta-Analysis of RCTs Assessing Efficacy of Lifestyle Interventions on Glycemic Control in South Asian Adults with Type 2 Diabetes
Background/Objective: The rising prevalence of Type 2 Diabetes Mellitus (T2DM), coupled with sedentary behavior and an increase in obesity rates in South Asian countries, calls for effective management strategies. We aimed to assess the efficacy of lifestyle interventions on glycemic control among…
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Artikel Jurnal Teks lengkap
The Mouth–Mind Connection: Interplay of Oral and Mental Health in Older Adults
The global population aged 65 and older is expected to double from 761 million in 2021 to 1.6 billion by 2050. Despite often being treated separately in clinical practice and policy, oral health and mental health are fundamentally interconnected in older adulthood, forming a bidirectional…
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Artikel Jurnal Teks lengkap
People Living in Places with Limited Illuminance Declare Better Health and Higher Quality of Life in Environmental and Physical Domains
Background. Exposure to artificial light at night can lead to circadian disruption and health risks. It can cause mood swings, confusion, and depression. The aim of this cross-sectional study was to assess the relationship between the illuminance of urban lighting and the health of residents…
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