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Artikel Jurnal Teks lengkap
Zero Dollar Drug Copay program improves antidiabetic medication adherence and medication use patterns among Blue Cross and Blue Shield of Louisiana members with diabetes in Louisiana
OBJECTIVE: Blue Cross and Blue Shield of Louisiana (BCBSLA) launched a zero-dollar co-pay (ZDC) pharmacy benefit on July 1, 2020, to reduce cost-related barriers to diabetes medications. This study evaluated the program’s effect on antidiabetic medication adherence and use patterns. RESEARCH DESIGN…
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Comparative analysis of child restraint system use in nine cities: a multiround cross-sectional observational study
INTRODUCTION: Road traffic injuries are a leading cause of death in children worldwide. Over 90% of road traffic deaths occur in low-income and middle-income countries. Unfortunately, there is very little data on child restraint system (CRS) use in major regions globally. Using data from nine…
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Prevalence and correlates of mental health difficulties in young Ghanaian children
BACKGROUND: Although 90% of youth live in low- and middle-income countries, only 10% of child mental health research is conducted in these settings. We sought to shed light on the mental health of Ghanaian children by estimating the prevalence of socioemotional difficulties and examining…
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Developing and testing bolt-on enhanced EQ-5D-5L for assessing Chinese patients with chronic obstructive pulmonary disease: a mixed-methods study protocol
INTRODUCTION: The EuroQol five dimensions questionnaire (EQ-5D) is widely used as a health-related quality of life (HRQoL) measure worldwide, but its sensitivity in detecting changes in health status among individuals with chronic obstructive pulmonary disease (COPD) remains suboptimal. Adding…
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The intersection of emergency care, human resources and health equity: a comparative mapping of policy and systems in Australia, Canada, Rwanda and South Africa
Strengthening systems of emergency healthcare is crucial to achieving global and national health goals. One of the key challenges in improving emergency care systems is the insufficient attention given to human resources for health (HRH) tasked with delivering this care. The intersection of…
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Evaluating the efficacy of aerobic exercise as therapy for depression and anxiety in women with PCOS: a systematic review
OBJECTIVE: This systematic review aims to evaluate the effectiveness of exercise interventions in alleviating depression and anxiety symptoms in women with polycystic ovary syndrome (PCOS). DATA SOURCES: PubMed, CINAHL, Cochrane Library, SportDiscus, EMBASE and Web of Science databases were…
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Inhibition of GALNT7 suppresses cell proliferation and invasiveness while elevating cell apoptosis via the inactivation of the AKT pathway in non-small cell lung cancer
OBJECTIVE: Polypeptide N-acetylgalactosaminyltransferase 7 (GALNT7) is a glycopeptide transferase which is closely involved in the development and progression of cancer. This study aimed to investigate the effects of GALNT7 inhibition on non-small cell lung cancer (NSCLC) cell proliferation…
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Adverse childhood experience among patients with severe mood disorders in Gedeo Zone Public Hospitals, Southern Ethiopia:A multisite cross-sectional study
ABSTRACTS: OBJECTIVE: To assess prevalence and associated factors of adverse childhood experiences (ACEs) among patients with severe mood disorders (SMDs). DESIGN: An institution-based cross-sectional study. SETTING: Gedeo Zone Public Hospitals, Southern Ethiopia. PARTICIPANTS: 374 patients with…
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How doctors present treatment options in advanced lung cancer consultations: a conversation analytic study
BACKGROUND: To facilitate shared decision-making (SDM), it is important that doctors clearly present the decision to be made and the available treatment options to the patient. This study explored how treatment options after first-line therapy were presented in advanced lung cancer consultations…
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National access to renal transplantation and post-transplant survival among patients with diabetes: deceased and living donor outcomes
INTRODUCTION: In the USA, patients with diabetes and end-stage renal disease are less likely to undergo deceased donor kidney transplantation (DDKT) or living donor kidney transplantation (LDKT). We explored the survival benefit of DDKT and LDKT among patients with diabetes. RESEARCH DESIGN AND…
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Cystatin C for predicting acute kidney injury in critically ill children with bacterial infections: a retrospective cohort study
BACKGROUND: Acute kidney injury (AKI) is a common and severe complication in paediatric intensive care units (PICUs), particularly among children with bacterial sepsis. Although the epidemiology of sepsis-associated AKI is well described, reliable biomarkers to predict both its onset and associated…
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Development of a personal recovery questionnaire for older adults with bipolar: a qualitative integrated knowledge translation approach
ABSTRACT: OBJECTIVES: To report on the development and refinement of a questionnaire of personal recovery for use by older adults with bipolar disorder. DESIGN: An integrated knowledge translation approach was used to structure collaboration of individuals with clinical, research and service users…
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Vδ1 T-cell subset appears to be responsive to PD-1 blockade therapy and is associated with survival in melanoma
BACKGROUND: Although most studies of anticancer T-cell immunity focus on αβ T cells, γδ T cells are attracting increasing attention due to their involvement in antitumor immune responses in various cancer entities, including melanoma. While immune checkpoint blockade (ICB) using the antagonistic…
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Impact of vitamin D non-reimbursement policy on therapy discontinuation in the general and rheumatic population in the Netherlands: a cross-sectional study
ABSTRACT: OBJECTIVE: To assess the impact of the non-reimbursement policy on vitamin D therapy discontinuation in patients from the general and rheumatic populations. DESIGN: A cross-sectional study. SETTING: Research institute specialised in health research and two outpatient pharmacies in the…
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Determinants of Helicobacter pylori infection and eradication failure among healthcare workers in a high-exposure clinical setting: a single-centre retrospective cohort study in China
ABSTRACT: OBJECTIVE: Healthcare workers (HCWs) are at potential risk of Helicobacter pylori (H. pylori) infection due to occupational exposure, yet epidemiological data in this population remain scarce. This study aimed to investigate the prevalence, risk factors, eradication efficacy and…
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Cardiovascular disease risk perception and stages of preventive behaviours: a community survey in Pokhara Metropolitan, Nepal
ABSTRACT: OBJECTIVES: Cardiovascular diseases (CVDs) are a leading cause of mortality in Nepal. Risk perception is crucial for the prevention of CVD-related behaviours. This study assessed CVD risk perceptions and the stages of preventive behaviours among adults in Pokhara Metropolitan, Nepal by…
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Comprehensive characterisation of individuals with fibrotic interstitial lung disease: baseline insights from the INJUSTIS study
BACKGROUND: Interstitial lung disease (ILD) represents a group of complex parenchymal conditions characterised by varying clinical trajectories. The It’s Not JUST Idiopathic Pulmonary Fibrosis Study seeks to identify genetic, proteomic and clinical biomarkers that distinguish rapidly progressive…
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Impact of international observerships on Ukrainian healthcare professionals during the war: a cross-sectional survey study
BACKGROUND: This cross-sectional survey study evaluates the influence of international observerships organised by the coalition of healthcare professionals from academic institutions—the Ukrainian Alliance for Medical Exchange and Development (UA-MED)—on the professional development, knowledge…
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Patterns of spinal new bone formation in patients with axial spondyloarthritis, psoriatic arthritis, rheumatoid arthritis and healthy controls: a low-dose CT study
OBJECTIVE: This study (the SpACT study) aimed to investigate the frequency and localisations of different types of spinal new bone formation (NBF) in patients with axial spondyloarthritis (axSpA), psoriatic arthritis (PsA), rheumatoid arthritis (RA) and healthy controls (HCs) using low-dose CT…
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Parental asthma and risk of offspring asthma from childhood to adolescence: a population-based cohort study
BACKGROUND: Maternal asthma has been associated with a higher risk of asthma in early childhood compared with paternal asthma, but it is unclear whether this difference persists into adolescence. METHODS: We analysed 55 643 children from the Norwegian Mother, Father and Child Cohort Study. Parental…
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