26,714,015 results
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Journal Article
The impact of night shift work on cortisol secretion
Night-shift work poses significant challenges to human health, largely through disruption of circadian rhythms and dysregulation of cortisol secretion. Cortisol, a key glucocorticoid, regulates metabolism, immune function, and stress responses, following a distinct diurnal pattern characterized by…
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Journal Article
Vegetarian Diets and Skeletal Integrity: Mechanisms, Risks, and Future Perspectives
Background. Osteoporosis affects over 200 million people worldwide. While vegetarian diets reduce risks of cardiovascular diseases, they raise concerns regarding the intake of nutrients key to skeletal homeostasis, such as vitamin B12 and calcium. Aim. This review analyzes the impact of vegetarian…
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Journal Article
Psychedelics in psychiatric treatment: a literature review
Background: Psychedelic substances have been used for millennia in religious and healing contexts and have recently re-emerged as subjects of scientific interest due to advances in neuroscience and psychiatry. Research suggests that psychedelics may address limitations of conventional psychiatric…
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Journal Article
The Risks and Benefits of Skiing on Pregnancy
Background: Participating in skiing during pregnancy raises clinical concerns about maternal and fetal safety due to the physiological demands of endurance activity, environmental exposure, and potential injury risk. While regular physical activity is widely acknowledged to have maternal and fetal…
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Journal Article
The Role Physical Activity in the Prevention and Control of Diabetes Mellitus – A Narrative Review
Diabetes mellitus is one of the most prevalent chronic non-communicable diseases worldwide and constitutes a major public health challenge due to its growing incidence, high morbidity and mortality, and substantial socioeconomic burden. Insufficient physical activity has been identified as a key…
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Journal Article
Atypical pneumonia – etiology, epidemiology, clinical presentations, diagnosis and treatment – a review of literature
Community-acquired pneumonia is a prevalent infectious disease with significant global morbidity and mortality. Atypical pneumonia, is characterized by milder symptoms and different pathogens, including Mycoplasma pneumoniae, Chlamydophila pneumoniae, and Legionella spp. Unlike typical pneumonia…
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Journal Article
The use of machine learning methods in the diagnosis of depression - a systematic review
Introduction: Nowadays, depression is one of the most common illnesses, affecting over 300 million people worldwide. Over the course of a lifetime, several dozen percent of the adult population of various ages and backgrounds will experience it. Depression is a debilitating disorder characterized…
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Journal Article
Prenatal and Early-Life Exposure to Parabens: Sources, Reduction Strategies, and Developmental Health Effects - A literature review
Informations and purpose: Parabens are widely used preservatives found in cosmetics, pharmaceuticals, foods and household products. Increasing evidence shows that women of reproductive age, including pregnant women, are consistently exposed to these endocrine-disrupting chemicals, which may…
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Journal Article
Effectiveness of the Milwaukee Protocol in Human Rabies: A Review
Introduction Human rabies remains almost invariably fatal once clinical symptoms appear, despite widespread use of pre- and post-exposure prophylaxis. The so-called “Milwaukee Protocol” — a structured regimen of therapeutic coma, NMDA antagonists, antivirals and supportive care — generated intense…
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Journal Article
The role of lifestyle and diet in the course of cataract: a literature review
Introduction: Cataract, a progressive and largely irreversible opacification of the lens, remains a leading cause of visual impairment and blindness globally, with significant medical, social, and economic consequences. While aging is the main risk factor, lifestyle and environmental factors also…
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Journal Article
Non-Suicidal Self-Injury (NSSI) in Borderline Personality Disorder: Dynamic Mechanisms, Cascading Models, and Psychosocial Outcomes in the Context of Specialist Interventions
Background. Non-suicidal self-injury (NSSI) occurs in 69-90% of women with borderline personality disorder (BPD) and represents a critical diagnostic criterion and therapeutic challenge. Despite its high prevalence and clinical significance, the dynamic psychological and neurobiological mechanisms…
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Journal Article
Obesity-Related Chronic Kidney Disease: Current State of Knowledge
Introduction: Obesity and chronic kidney disease are a growing global health problem that often coexist1. Obesity is an independent risk factor for CKD, promoting kidney damage through hemodynamic and metabolic mechanisms2. Aim of the study: This article aims to summarize current evidence on…
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Journal Article
Breast Cancer Risk in Users of Hormonal Contraception
Combined oral contraceptives (COCs) are a widely used method of birth control among women. They have a low Pearl Index, confirming high efficacy. Their mechanism of action relies on suppression of ovulation. This is achieved through the influence of estrogenic and progestogenic components on the…
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Journal Article
Understanding Tietze’s Syndrome: A Rare and Often Overlooked Cause of Anterior Chest Wall Pain
Introduction: Tietze’s syndrome is a rare, non-purulent arthropathy, most commonly associated with pain, swelling and tenderness in the 2nd and 3rd sternocostal junctions. Since its first description in 1921 many theories regarding the etiology and pathophysiology have been put forth, with a number…
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Journal Article
Recovery after patella fracture - case report
Introduction: The aim of this study is to present the rehabilitation process of a patient after a comminuted patellar fracture, with particular emphasis on the physiotherapeutic methods applied and their impact on the recovery of knee joint function. The study is a case report and includes an…
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Journal Article
Unlocking the Burp Reflex: A Review of Retrograde Cricopharyngeal Dysfunction
Introduction: The aim of this review is to synthesize current evidence on retrograde cricopharyngeal dysfunction in light of the rapidly expanding literature, summarizing contemporary knowledge on its pathophysiology, diagnosis, and management. Additionally, this study highlights challenges related…
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Journal Article
The Role of Prehabilitation on Functional Outcomes After Radical Prostatectomy: A Scoping Review
Background Radical prostatectomy is a primary treatment for localized prostate cancer but often results in urinary incontinence and erectile dysfunction, significantly impacting patient quality of life. Prehabilitation, defined as the optimization of physical capacity before surgery—aims to…
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Journal Article
Use of Psychotropic Medications in Athletes: Clinical and Legal Aspects - Narrative review
Background: Mental health disorders are increasingly recognized among athletes and may affect performance, well-being, and career longevity. Pharmacological treatment is often required; however, the use of psychotropic medications in athletes raises specific clinical concerns related to safety…
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Journal Article
The Role of Yoga in Cardiovascular Prevention and Rehabilitation - A Structured Narrative Review
Background: Yoga is increasingly used as an adjunct mind–body intervention in cardiovascular prevention and rehabilitation, with proposed effects on stress regulation and autonomic balance. Aim: To summarize evidence on yoga-based interventions in cardiovascular disease and cardiac rehabilitation…
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Journal Article
Comprehensive Analysis of Therapeutic Strategies for Mycoplasma pneumoniae Infections: A Global and European Review of Current Antibiotic Treatment Standards in Paediatric and Adult Populations in an Era of Increasing Antimicrobial Resistance
Background. Mycoplasma pneumoniae infections remain a significant clinical challenge, particularly in the paediatric population, where they constitute a common cause of community-acquired pneumonia (CAP). The absence of a cell wall results in intrinsic resistance to beta-lactam antibiotics…
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