11,943,971 results
Showing 81–100 · 3.60 seconds · RSS
-
Journal Article Full text
Leveraging Representation Learning for Bi-parametric Prostate MRI to Disambiguate PI-RADS 3 and Improve Biopsy Decision Strategies
OBJECTIVES: Despite its high negative predictive value (NPV) for clinically significant prostate cancer (csPCa), MRI suffers from a substantial number of false positives, especially for intermediate-risk cases. In this work, we determine whether a deep learning model trained with PI-RADS–guided…
-
Journal Article Full text
Computational Analysis of Intravascular OCT Images for Future Clinical Support: A Comprehensive Review
Over the past two decades, intravascular optical coherence tomography (IVOCT) has emerged as a promising tool for planning percutaneous coronary interventions (PCI), studying coronary artery disease, and assessing treatments. With its near-histological resolution and optical contrast, IVOCT…
-
Journal Article Full text
A Trust-Guided Approach to MR Image Reconstruction with Side Information
Reducing MRI scan times can improve patient care and lower healthcare costs. Many acceleration methods are designed to reconstruct diagnostic-quality images from sparse [Formula: see text]-space data, via an ill-posed or ill-conditioned linear inverse problem (LIP). To address the resulting…
-
Journal Article Full text
Connectome of a human foveal retina
The fovea is a unique specialization of the primate retina and is a promising site for obtaining the first complete connectome of a human central nervous system (CNS) structure. Within the fovea, neural cells and circuits have been miniaturized and compressed during evolution to sample the visual…
-
Journal Article Full text
Isoform-Specific Control of Adipose Thermogenesis by the miR-27 Family Reveals Antagonism within a Polycistronic miRNA Cluster
MicroRNAs (miRNAs) are frequently encoded within polycistronic clusters thought to function as coherent regulatory units, yet whether individual cluster members act cooperatively or exert distinct physiological effects remains unclear. miR-27a and miR-27b are closely related miRNAs located within…
-
Journal Article Full text
IMPACT OF BOWEL DIARY COMPLETION AND EDUCATION ON FECAL INCONTINENCE SEVERITY
OBJECTIVES: To determine the impact of run-in period on fecal incontinence (FI) symptom severity. STUDY DESIGN: Planned secondary analysis of the run-in to a study evaluating impact of 12-week treatment with percutaneous tibial nerve stimulation versus sham in reducing FI severity in women. All…
-
Journal Article Full text
Worker and Restaurant Characteristics Associated with Food Safety Culture: An Environmental Health Specialists Network Study
More than 800 foodborne illness outbreaks have been reported to the United States Centers for Disease Control and Prevention (CDC) annually. Researchers have suggested that improving food safety culture in restaurants (i.e., shared values, beliefs, and norms about food safety) is an important way…
-
Journal Article Full text
Developing magnetic resonance imaging biomarkers of neuroinflammation, cognitive impairment and survival outcomes for radiotherapy-induced brain injury in a preclinical mouse model
OBJECTIVE: Radiotherapy-induced brain injury (RIBI) is a chronic side effect that affects up to 90% of brain tumor survivors treated with radiotherapy. Here, we used multi-parametric magnetic resonance imaging (MRI) to identify noninvasive and clinically translatable biomarkers of RIBI. METHOD…
-
Journal Article Full text
Effects of the COVID-19 pandemic on TB outcomes in the United States: a Bayesian analysis
BACKGROUND: Tuberculosis (TB) notifications and deaths in the United States fluctuated substantially during the COVID-19 pandemic. We analyzed multiple data sources to understand the factors contributing to these changes and estimated future TB trends. METHODS: We identified four mechanisms…
-
Journal Article Full text
Barbed Suture Strength in Sacrocolpopexy: Does Pattern Matter?
IMPORTANCE: While barbed suture in sacrocolpopexy is becoming increasingly common, an accepted vaginal attachment pattern for barbed suture has not been established. OBJECTIVES: This study aims to compare the structural properties of three different barbed suture attachment patterns used to fixate…
-
Journal Article Full text
Improving Quality of Mortality Estimates Among Non-Hispanic American Indian and Alaska Native People, 2020
Racial misclassification on death certificates leads to inaccurate mortality data for American Indian and Alaska Native (AI/AN) populations. We describe methods for correcting for racial misclassification among non-Hispanic AI/AN (NH-AI/AN) populations using data from the year 2020. We linked…
-
Journal Article Full text
Can pharmacogenetics be used to predict the response to fesoterodine fumarate?
IMPORTANCE: Pharmacogenetics could address the challenge of predicting an individual’s response to anticholinergic medications for urgency urinary incontinence (UUI). OBJECTIVE: Our objectives were to evaluate whether the metabolizer status of cytochrome p450 2D6 (CYP2D6), the drug metabolizing…
-
Journal Article Full text
Don’t Stress: We’re One Step Closer to Host-Directed Therapy for Influenza
-
Journal Article Full text
Correlates of Survivors’ Satisfaction with Informal Support Relationships Following Sexual Assault Disclosure
Sexual assault (SA) is a prevalent issue that can impact survivors’ relationships. Most research has examined the effects of SA on couples, with much less research examining effects on relationships with friends and family. The current study examined correlates of survivor’s relationship…
-
Journal Article Full text
Selecting and tailoring implementation strategies for deimplementing fall prevention alarms in US hospitals: a group concept mapping study
OBJECTIVES: Many hospitals use fall prevention alarms, despite the limited evidence of effectiveness. The objectives of this study were (1) to identify, conceptualise and select strategies to deimplement fall prevention alarms and (2) to obtain feedback from key stakeholders on tailoring selected…
-
Journal Article Full text
Trimester-Dependent Vertical Transmission of H5N1 Influenza Virus Through Placental and Mammary Routes Impairs Offspring Development
Avian influenza H5N1 has pandemic potential and historically has caused more severe disease in pregnant women than the general population. With increasing transmission of H5N1 detected among placental mammals, animal models are necessary for testing countermeasures, including during pregnancy…
-
Journal Article Full text
The Influence of Safety Performance on Competitive Advantage in the Shipping Industry: A Systematic Literature Review Study
This study analyzes research trends and developments related to Safety Performance and its implementation solutions through the Systematic Literature Review (SLR) based on Scopus data from 1919 to 2023. The results showed a significant increase in publications, especially after 2000, reflecting…
-
Journal Article Full text
Early Postnatal Polymerase Chain Reaction Testing in the Identification of Perinatal Transmission of Hepatitis C Virus
In this study, a single hepatitis C virus (HCV) RNA at 2–6 months was sensitive and specific (86.7% and 95% confidence interval [CI], 62.1%–96.3% and 100% and 95% CI, 98.8%–100%, respectively) in identifying perinatal transmission of HCV. No cases of perinatal infection requiring treatment were…
Showing at most 50 pages. Narrow your search with filters for more specific results.