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Norepinephrine release from Locus Ceruleus:a central regulator for the CNS spatio-temporal activation pattern?

Marco Atzori; Roberto Cuevas-Olguin; Eric Esquivel-Rendon dkk.

Frontiers in Synaptic Neuroscience, Vol. 8 · 2016 · Inggris · DOAJ Scopus

Norepinephrine (NE) is synthesized in the Locus Coeruleus (LC) of the brainstem, from where it is released by axonal varicosities throughout the brain via volume transmission. A wealth of data from clinics and from animal models indicates that this catecholamine coordinates the activity of the…