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8 results for "Li-Te Lin"

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  1. Journal Article

    Melatonin supplementation attenuates cuproptosis and ferroptosis in aging cumulus and granulosa cells: potential for improving IVF outcomes in advanced maternal age

    Kuan-Hao Tsui; Chia-Jung Li; Li-Te Lin

    Reproductive Biology and Endocrinology, Vol. 22 No. 1 · 2024 · English · DOAJ Scopus

    Abstract Background Advanced maternal age is associated with decreased oocyte quantity and quality and in vitro fertilization (IVF) success rates. This study aimed to investigate whether melatonin supplementation can improve IVF outcomes in women of advanced maternal age by modulating cuproptosis…

  2. Journal Article

    Improvement of early miscarriage rates in women with adenomyosis via oxytocin receptor antagonist during frozen embryo transfer-a propensity score-matched study

    Po-Wen Lin; Chyi-Uei Chern; Chia-Jung Li et al.

    Reproductive Biology and Endocrinology, Vol. 22 No. 1 · 2024 · English · DOAJ Scopus

    Abstract Background Dysfunctional uterine peristalsis seems to play a pivotal role in hindering embryo implantation among women diagnosed with adenomyosis. This research aims to investigate whether administering an oxytocin receptor antagonist during a frozen embryo transfer (FET) cycle using a…

  3. Journal Article

    Additional single dose GnRH agonist during luteal phase support may improve live birth rate in GnRHa-HRT frozen–thawed embryo transfer cycle: a retrospective cohort study

    Wei-Shan Chang; Pei-Hsuan Lin; Chia-Jung Li et al.

    BMC Pregnancy and Childbirth, Vol. 23 No. 1 · 2023 · English · DOAJ Scopus

    Abstract Background GnRH agonist (GnRHa) has been reported to have direct effects and functional roles in the endometrium and embryos. Several meta-analyses have shown that GnRHa administration in the luteal phase improved the live birth rate or pregnancy rate in both fresh and frozen embryo…

  4. Journal Article Full text

    The Translational Role of miRNA in Polycystic Ovary Syndrome: From Bench to Bedside—A Systematic Literature Review

    Salvatore Giovanni Vitale; Anna Maria Fulghesu; Mislav Mikuš et al.

    Biomedicines, Vol. 10 No. 8 · 2022 · English · DOAJ Scopus

    MicroRNAs (miRNAs) are small, non-coding RNAs that are essential for the regulation of post-transcriptional gene expression during tissue development and differentiation. They are involved in the regulation of manifold metabolic and hormonal processes and, within the female reproductive tract, in…

  5. Journal Article Full text

    Abnormal Uterine Bleeding in Perimenopausal Women: The Role of Hysteroscopy and Its Impact on Quality of Life and Sexuality

    Salvatore Giovanni Vitale; Rafał Watrowski; Fabio Barra et al.

    Diagnostics, Vol. 12 No. 5 · 2022 · English · DOAJ Scopus

    Abnormal uterine bleeding (AUB) is a frequent symptom in perimenopausal women. It is defined as uterine bleeding in which the duration, frequency, or amount of bleeding is considered excessive and negatively affects the woman’s quality of life (QoL) and psychological well-being. In cases of…

  6. Journal Article

    Mitochondrial quality control as a central pharmacological target in aging

    Kuan-Hao Tsui; Shih-Hsuan Cheng; Boyang Wang et al.

    Pharmacological Research, Vol. 227 · 2026 · English · DOAJ Scopus

    Mitochondrial dysfunction is a convergent hallmark of biological aging and a mechanistically attractive target for gerotherapeutic development. Yet translation of mitochondria-focused interventions has been limited by pathway complexity, tissue heterogeneity, and insufficiently harmonized…

  7. Journal Article

    Artificial oocyte activation may improve embryo quality in older patients with diminished ovarian reserve undergoing IVF-ICSI cycles

    Tzung-En Tsai; Pei-Hsuan Lin; Pei-Fen Lian et al.

    Journal of Ovarian Research, Vol. 15 No. 1 · 2022 · English · DOAJ Scopus

    Abstract Background Artificial oocyte activation (AOA) is used to improve fertilization rate following fertilization failure after intracytoplasmic sperm injection (ICSI). Several studies have also shown that AOA may be involved in embryo development. Women with poor ovarian response are more…