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Artikel Jurnal Teks lengkap
Umami Responses in Mouse Taste Cells Indicate More than One Receptor
A number of gustatory receptors have been proposed to underlie umami, the taste of l-glutamate, and certain other amino acids and nucleotides. However, the response profiles of these cloned receptors have not been validated against responses recorded from taste receptor cells that are the native…
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Motor system activation after subcortical stroke depends on corticospinal system integrity
Movement-related brain activation patterns after subcortical stroke are characterized by relative overactivations in cortical motor areas compared with controls. In patients able to perform a motor task, overactivations are greater in those with more motor impairment. We hypothesized that…
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Model of Formin-Associated Actin Filament Elongation
Formin FH2 domains associate processively with actin-filament barbed ends and modify their rate of growth. We modeled how the elongation rate depends on the concentrations of profilin and actin for four different formins. We assume that (1) FH2 domains are in rapid equilibrium among conformations…
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Strategies optimize the detection of motion transients
Strategies are implicitly formed when a task is consistent and can be used to improve performance. To investigate how strategies can alter perceptual performance, I trained animals in a reaction time (RT) detection task in which the probability of a fixed duration motion pulse appearing varied over…
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Artikel Jurnal Teks lengkap
Illness Intrusion and Psychological Adjustment to Rheumatic Diseases: A Social Identity Framework
OBJECTIVE: To examine the extent to which arthritis intruded upon 4 social roles (spouse, homemaker, parent, worker). In accordance with propositions set forth by social identity theory and the identity-relevant stress hypothesis, we hypothesized that 1) illness intrusion would predict…
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Artikel Jurnal Teks lengkap
Non-invasive mapping of corticofugal fibres from multiple motor areas—relevance to stroke recovery
Recovery of motor function after subcortical stroke appears to be related to the integrity of descending connections from the ipsilesional cortical motor system, a view supported by the observation of greater than normal movement-related activation in ipsilesional motor regions in chronic…
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Longitudinal Changes in Cerebral Response to Proprioceptive Input in Individual Patients after Stroke: An fMRI Study
OBJECTIVE: Functional magnetic resonance imaging (fMRI) provides an opportunity to study the relationship between cerebral reorganization and functional recovery after stroke. The authors set out to demonstrate the feasibility of using fMRI to investigate mechanisms of recovery in individual…
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Artikel Jurnal Teks lengkap
Iron overload due to mutations in ferroportin
Iron overload disease due to mutations in ferroportin has a dominant inheritance and a variable clinical phenotype, such that some patients show early Küpffer cell iron loading and low transferrin saturation, while others show hepatocyte iron loading and high transferrin saturation. Studies…
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Molecular and clinical correlates in iron overload associated with mutations in ferroportin
Mutations in ferroportin (Fpn) result in iron overload. We correlate the behavior of three Fpn mutants in vitro with patients’ phenotypes. Patients with Fpn mutations A77D or N174I showed macrophage iron loading. In cultured cells, FpnA77D did not reach the cell surface and cells did not export…
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West Nile virus meningoencephalitis
Since its first appearance in the US in 1999, West Nile virus (WNV) has emerged as the most common cause of epidemic meningoencephalitis in North America. In the 6 years following the 1999 outbreak, the geographic range and burden of the disease in birds, mosquitoes and humans has greatly expanded…
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Artikel Jurnal Teks lengkap
Nitric oxide-dependent changes in Schistosoma mansoni gene expression
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Artikel Jurnal Teks lengkap
Estimation of distribution state of carboxyl groups within submicron-sized, carboxylated polymer particle with isothermal titration calorimeter
A novel technique to estimate the distribution state of carboxyl groups within submicron-sized, carboxylated polymer particles was proposed. For the purpose, carboxyl groups in two kinds of butyl methacrylate–methacrylic acid copolymer emulsion, which were prepared by emulsion copolymerizations…
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Control on shape, porosity and surface hydrophilicity of hematite particles by using polymers
The shape, porosity, and surface hydrophilicity of hematite particles formed from a forced hydrolysis reaction of acidic FeCl(3) solution were controlled by using a trace of polymers (0.001 and 0.003 wt%). The spherical particles were produced on the systems with polyvinyl alcohol (PVA) and…
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Preparation of silver-poly(acrylamide-co-methacrylic acid) composite microspheres with patterned surface structures
Acrylamide (AM) and methacrylic acid (MAA) copolymer microgels were prepared by a reverse suspension polymerization technique. The microgels were used as templates for the preparation of silver-poly(acrylamide-co-methacrylic acid) [Ag-P(AM-co-MAA)] composite microspheres. The surface structures of…
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Microwave-assisted synthesis and micellization behavior of soy-based copoly(2-oxazoline)s
Polymers based on renewable resources are promising candidates for replacing common organic polymers, and thus, for reducing oil consumption. In this contribution we report the microwave-assisted synthesis of block and statistical copolymers from 2-ethyl-2-oxazoline and 2-“soy alkyl”-2-oxazoline…
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The elastic properties of single double-stranded DNA chains of different lengths as measured with optical tweezers
Optical tweezers are microscopic tools with extraordinary precision in the determination of the position (±2 nm) of a colloid (diameter: ∼2.0 μm) in 3D-space and in the measurement of small forces in the range between 0.1 and 100 pN (pN=10(−12) N). Experiments are reported in which single…
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Non-ionic amphiphilic block copolymers by RAFT-polymerization and their self-organization
Water-soluble, amphiphilic diblock copolymers were synthesized by reversible addition fragmentation chain transfer polymerization. They consist of poly(butyl acrylate) as hydrophobic block with a low glass transition temperature and three different nonionic water-soluble blocks, namely, the…
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Effect of thiol-containing monomer on the preparation of temperature-sensitive hydrogel microspheres
The main objective of this study is to prepare, thermally, sensitive microgel particles bearing thiol groups via precipitation polymerization of N-isopropylacrylamide (NIPAM), methylenebisacrylamide (MBA) and vinylbenzylisothiouronium chloride (VBIC) using…
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Electroosmotic flow velocity measurements in a square microchannel
Experiments were performed using a microparticle image velocimetry (MPIV) for 2D velocity distributions of electroosmotically driven flows in a 40-mm-long microchannel with a square cross section of 200×200 μm. Electroosmotic flow (EOF) bulk fluid velocity measurements were made in a range of…
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Ultraslow dynamics in asymmetric block copolymers with nanospherical domains
Low shear rate and low frequency measurements focused on the extremely slow dynamics of a three-dimensional body-centered cubic (BCC) structure of an asymmetric block copolymer under nanophase-separated conditions. The material studied was poly(styrene-b-ethylene-co-butylene-b-styrene) swollen in a…
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